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Principal Scientist Jobs

88 Job Offers

Principal Data Scientist, Ads
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Lead the future of Reddit’s ad marketplace as a Principal Data Scientist. Drive strategic innovation in auction design, causal inference, and advertiser ROI using advanced statistics and machine learning. Partner with Product and Engineering to build scalable solutions. This remote US role offers...
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268000.00 - 365100.00 USD / Year
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Until further notice
Principal Data Scientist - Rentals Shopping
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Principal Data Scientist sought to lead the Rentals Shopping pillar at Zillow, driving data strategy for the rental consumer journey. You will partner with product leadership to shape roadmaps using advanced modeling, causal inference, and experimentation at scale. Requires a PhD/Master’s, 8+ yea...
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United States, Remote-USA
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178300.00 - 284700.00 USD / Year
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Until further notice
Principal Optical Scientist
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Join Microsoft Research in Cambridge, UK as a Principal Optical Scientist to shape next-gen AI infrastructure. You will lead high-risk optical system design, modelling, and simulation using Zemax and Python, bridging research with production. This role requires a Doctorate in Optics or equivalent...
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Not provided
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Principal Data Scientist
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Join Microsoft’s ISE team as a Principal Data Scientist in Atlanta. You’ll solve complex customer challenges, develop cloud-based solutions, and drive data strategy. Requires a PhD/MS in Data Science or related field with 5+ years experience. Enjoy a competitive benefits package while innovating ...
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139900.00 - 274800.00 USD / Year
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Until further notice
Principal Data Scientist & Analytics
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Join Microsoft’s Monetization Marketplace Team as a Principal Data Scientist & Analytics leader in Redmond, WA. Drive data-driven decisions by defining metrics, designing experiments, and delivering actionable insights across engineering and product teams. Requires a PhD/Master’s in Data Science,...
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139900.00 - 274800.00 USD / Year
Expiration Date
Until further notice
Principal Data Scientist
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Microsoft seeks a Principal Data Scientist to drive data-driven solutions in a dynamic, cloud-enabled environment. You will partner with engineering, finance, and sales teams to transform large-scale telemetry into actionable insights, defining quota strategies and applying machine learning. Idea...
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Location
United States, Multiple Locations
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Salary
142800.00 - 304200.00 USD / Year
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Until further notice
Principal Data Scientist
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Principal Data Scientist role in the West Midlands, UK. Lead advanced analytics, machine learning, and AI solution delivery across client programmes. Requires deep expertise in statistics, model validation, and setting coding standards. Drive responsible AI practices, mentor teams, and influence ...
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Location
United Kingdom, West Midlands
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Not provided
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Principal Applied Scientist
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Join Microsoft AI as a Principal Applied Scientist in Redmond, WA, to architect next-gen recommendation systems using LLMs and GenAI. You will design deep learning ranking models and agentic systems for large-scale content feeds. Ideal for a senior leader with expertise in ML/DL pipelines and a P...
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Salary
139900.00 - 304200.00 USD / Year
Expiration Date
Until further notice

About the Principal Scientist role

A Principal Scientist is a senior-level research and development leader who drives innovation by designing, building, and deploying advanced machine learning and artificial intelligence systems at scale. These professionals typically operate at the intersection of theoretical research and practical engineering, translating complex scientific concepts into production-ready solutions that power core business products and user experiences. Principal Scientist jobs are distinguished by their emphasis on strategic technical leadership, cross-functional collaboration, and high-impact problem solving.

The core responsibilities of a Principal Scientist often include architecting large-scale ML and deep learning pipelines, developing novel model architectures for ranking, recommendation, personalization, and generative AI systems. They are responsible for defining evaluation frameworks, designing experiments, and establishing metrics that accurately measure both system performance and user value. A significant portion of the role involves mentoring junior scientists and engineers, setting technical standards, and driving alignment across product, engineering, and data science teams. Principal Scientists also lead the integration of cutting-edge techniques such as large language models (LLMs), retrieval-augmented generation, agentic systems, and multi-objective optimization into existing infrastructure. They regularly communicate complex technical strategies to diverse stakeholders and act as trusted advisors on data-driven decision making.

Typical skills and requirements for Principal Scientist positions include an advanced degree (PhD or Master’s) in computer science, statistics, mathematics, operations research, or a related quantitative field, combined with extensive experience—often six to ten years or more—delivering production ML systems. Deep expertise in recommendation systems, search relevance, natural language processing, or generative AI is common. Proficiency in modern ML frameworks (e.g., PyTorch, TensorFlow), large-scale data processing (e.g., Spark), and cloud infrastructure is essential. Strong architectural skills for designing distributed, high-throughput services are critical, as is a solid publication record in top-tier conferences (e.g., NeurIPS, KDD, ICML, RecSys). Beyond technical depth, these roles demand exceptional communication, mentorship, and strategic influence abilities. Principal Scientist jobs are ideal for individuals who thrive on solving ambiguous, high-stakes challenges and driving measurable impact through scientific innovation and technical leadership.