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Senior Python Engineer Jobs

111 Job Offers

Senior Backend Engineer - Python / Threat Intelligence
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Senior Backend Engineer (Python) sought for a Prague-based threat intelligence team. You will design and deploy high-quality microservices, lead AI research, and optimize system performance. Requires 5+ years in backend development with Python, cloud computing (GCP/AWS), and databases (ElasticSea...
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Rapid7
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Senior Python Software Engineer
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Senior Python Software Engineer sought by a leading commodities trading firm in Houston. You will build high-performance, mission-critical systems for front-office trading desks, leveraging Python and AWS. This role requires 8+ years of experience and deep knowledge of energy markets. Join an eli...
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Hunter Bond
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Senior Software Engineer - Fullstack (Python + React)
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Seeking a Senior Fullstack Software Engineer with 7+ years of experience to join our team in Bengaluru. You will leverage deep expertise in Python (3+ years) and React (5+ years) to drive daily development. Key responsibilities include building microservices, managing CI/CD deployments on AWS/GCP...
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BlackLine
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Senior Python Integration Engineer (SCORM / LMS)
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Senior Python Integration Engineer (SCORM/LMS) – £400-£600/day, fully remote (UK/EU). Join a fast-growing AI startup to architect and build critical SCORM/LMS integrations for enterprise financial clients. Requires strong Python backend skills, proven SCORM 1.2 experience, and API/SSO expertise. ...
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Arrows Groupe
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Senior Python Software Engineer
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Senior Python Software Engineer sought to drive R&D tooling, CI/CD pipelines, and internal systems in Bristol. Requires 8+ years Python experience across Linux/Windows, GitLab CI/CD, and Agile workflows. Key skills include wxPython, ETL pipelines, and database optimisation. Join a collaborative t...
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70000.00 - 80000.00 GBP / Year
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Zenovo
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Senior Backend Python Engineer - AI Platform
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Senior Backend Python Engineer sought to architect scalable backend systems for a global financial institution’s AI Platform in London. You will design and deploy production-grade code using FastAPI, Kubernetes, and CI/CD, focusing on knowledge graph automation in Credit Risk. Requires deep Pytho...
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Citi
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Senior AI API & Gateway Engineer (Python)
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Senior AI API & Gateway Engineer (Python) in Bangalore. Design and operate high-throughput API infrastructure for Generative AI, managing LLM endpoints across cloud and on-premise. Requires deep expertise in API lifecycle, AI Gateways (Kong, Envoy), and agent orchestration (LangGraph, ADK). Own e...
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NTT DATA
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Senior Software Engineer- Python & Unix
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Senior Software Engineer (Python & Unix) sought for a Pune-based role. You will drive backend development using core Python, Pandas, and NumPy, requiring strong Unix and shell scripting skills. Ideal candidates possess systems thinking, experience with Git, Jira, and CI/CD pipelines. Banking doma...
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Citi
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Senior Python Engineer with GCP experience
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Senior Python Engineer with GCP expertise needed to build scalable, secure Healthcare applications. You will develop microservices and optimize Health Information Exchange (HISP) workflows using Python, Flask, and GCP tools like Cloud Run and BigQuery. Remote or office-based in Ukraine with flexi...
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N-iX
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Senior Software Engineer, Python Platform
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Senior Software Engineer, Python Platform at Uber in Amsterdam. Lead cross-cutting initiatives to build and operate the infrastructure powering AI/ML, data platforms, and backend services at scale. Requires 7+ years of experience, deep Python expertise, and a track record in distributed systems a...
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Uber
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Senior Data Software Engineer (Python & PySpark) - Vice President
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Senior Data Software Engineer (VP) sought in Singapore to lead large-scale data solutions using Python, PySpark, and Apache Spark. Requires 7+ years in data engineering, expertise in cloud platforms (AWS, Azure, GCP), and strong SQL/ETL skills. Drive high-impact projects, design distributed syste...
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Citi
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About the Senior Python Engineer role

Looking for Senior Python Engineer jobs means seeking a pivotal role at the intersection of deep technical expertise and strategic software development. A Senior Python Engineer is a seasoned professional responsible for designing, building, and maintaining robust, scalable, and efficient software systems using the Python programming language. This role transcends basic coding; it involves architectural decision-making, mentoring, and owning the full software development lifecycle to drive business-critical applications and platforms.

Professionals in these roles typically shoulder a wide array of responsibilities. They architect and implement backend services, RESTful APIs, and data processing pipelines. A core part of the job is writing clean, maintainable, and testable code while advocating for best practices in software engineering. They are expected to lead the technical direction of projects, making key decisions on frameworks, tools, and system design patterns to ensure reliability and scalability. Collaboration is fundamental, as Senior Python Engineers frequently partner with product managers, designers, and other engineering teams to translate complex requirements into technical specifications. They also play a crucial role in operational excellence, which includes monitoring system performance, troubleshooting production issues, and ensuring the security and robustness of applications. Furthermore, they often contribute to DevOps practices, enhancing CI/CD pipelines to streamline deployment and improve development velocity.

The typical skill set for Senior Python Engineer jobs is comprehensive. Mastery of Python and its ecosystem (e.g., frameworks like Django, Flask, or FastAPI) is a given. Strong experience with system design, data structures, algorithms, and software architecture principles is essential. Familiarity with cloud platforms (AWS, GCP, Azure), containerization technologies like Docker and Kubernetes, and infrastructure-as-code is highly common. A deep understanding of databases, both SQL (e.g., PostgreSQL) and NoSQL, is required. Beyond technical prowess, successful candidates demonstrate excellent problem-solving abilities, a product-oriented mindset, and strong communication skills to articulate complex concepts to diverse stakeholders. They exhibit a high degree of ownership, from initial concept through to deployment and maintenance. While requirements vary, most positions seek individuals with 5+ years of relevant experience, a proven track record of delivering complex systems, and a commitment to continuous learning and mentoring junior team members. Exploring Senior Python Engineer jobs opens doors to roles where technical leadership directly impacts product innovation and technological advancement.