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Senior Python Engineer Jobs

111 Job Offers

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Senior Software Engineer - Conversational AI (Python)
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Join Team Vector as a Senior Software Engineer in Estonia to build agentic voice AI for banking. Requires production AI systems experience, Python skills, and strong architecture judgment.
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Glia
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Senior Full-Stack Engineer — Application Experiences (Vue/React, Python)
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Senior Full-Stack Engineer role in Palo Alto building AI-powered enterprise apps with Vue/React, TypeScript, and Python. Requires 6+ years experience, LLM integration skills, and hybrid work with competitive pay.
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Evolver
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Senior Backend Software Engineer (Python / FastAPI)
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Senior Backend Engineer (Python/FastAPI) in San Francisco building real-time sensor data pipelines for defense tech. Requires strong Python, streaming systems, and end-to-end ownership. $140k-$240k base plus pre-IPO equity.
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CHAOS Industries
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Principal / Senior Principal Java & Python Engineer
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Senior Principal Java & Python Engineer in Atlanta. Hands-on role requiring Java 8-17, Spring Boot, REST APIs, microservices, and Python backend skills. Must be a U.S. citizen or Green Card holder able to work onsite.
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CONFISA INTERNATIONAL GROUP
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Senior Python Backend Engineer, Financial Systems
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Senior Python Backend Engineer for financial systems at AI-driven Makers. Fully remote (Argentina/Brazil), long-term contractor. Requires 5+ years Python, Django, SQL, financial APIs, and daily agentic AI coding tools like Claude and Cursor.
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BriteCore
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Senior Python Backend Engineer
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Senior Python Backend Engineer for a fully remote long-term contract (Argentina/Brazil). Requires 5+ years Python, Django, SQL, AWS, Docker and daily hands-on use of agentic AI coding tools like Claude and Cursor.
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BriteCore
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Senior Python Engineer – Engineered Index & Rates
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Senior Python Engineer role in London for FICC index and rates platforms. Requires 7+ years hands-on Python, strong SQL, Linux and CI/CD skills. Build scalable quantitative tools with hybrid benefits and wellbeing support.
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Lseg
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Senior Software Test Engineer (Python), Intelligence Systems
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Join Anduril as a Senior Software Test Engineer in Reston, VA. Leverage your Python and test automation expertise to validate advanced networking systems for defense technology. Active secret clearance required.
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Anduril Industries
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Senior AI Engineer, Agents (Python) (f/m/d)
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Senior AI Engineer role in Munich to own LLM agent quality for Bliro's chat and voice agents. Requires strong Python, eval pipelines, LLM judges and benchmarks. Hybrid setup, equity, 30 days PTO.
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Bliro GmbH
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Senior Backend Engineer (Python)- Application Infrastructure
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Senior Backend Engineer (Python) to build core infrastructure libraries and high-scale microservices in Tel Aviv. Requires 5+ years of backend experience, deep Python concurrency knowledge, and expertise with PostgreSQL, MongoDB, Kafka, and Redis.
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Gong
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Senior Full-Stack Software Engineer (Python, React)
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Senior Full-Stack Engineer role (Python, React) at an AI-first global tech company. Build scalable web apps, lead architecture, and work with LLM APIs. Remote/hybrid flexibility, international projects, and strong benefits.
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Exadel Inc (Website)
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Senior Backend Engineer (Python)- Application Infrastructure
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Senior Backend Engineer (Python) role in Tel Aviv to build core infrastructure libraries and high-scale microservices. Requires 5+ years with Python, deep concurrency knowledge, and experience with PostgreSQL, MongoDB, Kafka, and Redis.
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Gong.io
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Senior Python Backend Developer / ML Engineer (IR-555)
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Senior Python Backend Developer/ML Engineer needed to build scalable FastAPI systems and production LLM solutions. Requires 7+ years Python, 2+ years ML/LLM experience, RAG architectures, LangChain, and vector databases. Remote-friendly with flexible hours and growth opportunities.
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Intellectsoft
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Senior Backend Python Engineer (Core Gateway)
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Senior Backend Python Engineer needed for Core Gateway team at payabl. Remote from Poland. Requires 5+ years Python (FastAPI, AsyncIO), Perl flexibility, API integrations, Docker, AWS. Annual learning budget and global events.
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payabl
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Senior Software Test Engineer (Python, Pyspark, Databricks)
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NIQ seeks a Senior Software Test Engineer in Chennai to build scalable big data automation frameworks using Python, Pyspark, and Databricks on Azure. Requires 6-10 years of experience in cloud testing, SQL, and API automation.
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NielsenIQ
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Senior Engineer with Python, GenAI & Database systems
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NielsenIQ
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Senior Open-Source Python Engineer, ML Developer Tools - US Remote
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Hugging Face
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Senior Open-Source Python Engineer, ML Developer Tools - EMEA Remote
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Hugging Face
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Senior Python, Cloud Infrastructure & AI Engineer
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India, India
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Everbridge
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Senior Software Engineer (Backend, Python)
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United Kingdom, London (GB)
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Octopus Energy
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About the Senior Python Engineer role

Looking for Senior Python Engineer jobs means seeking a pivotal role at the intersection of deep technical expertise and strategic software development. A Senior Python Engineer is a seasoned professional responsible for designing, building, and maintaining robust, scalable, and efficient software systems using the Python programming language. This role transcends basic coding; it involves architectural decision-making, mentoring, and owning the full software development lifecycle to drive business-critical applications and platforms.

Professionals in these roles typically shoulder a wide array of responsibilities. They architect and implement backend services, RESTful APIs, and data processing pipelines. A core part of the job is writing clean, maintainable, and testable code while advocating for best practices in software engineering. They are expected to lead the technical direction of projects, making key decisions on frameworks, tools, and system design patterns to ensure reliability and scalability. Collaboration is fundamental, as Senior Python Engineers frequently partner with product managers, designers, and other engineering teams to translate complex requirements into technical specifications. They also play a crucial role in operational excellence, which includes monitoring system performance, troubleshooting production issues, and ensuring the security and robustness of applications. Furthermore, they often contribute to DevOps practices, enhancing CI/CD pipelines to streamline deployment and improve development velocity.

The typical skill set for Senior Python Engineer jobs is comprehensive. Mastery of Python and its ecosystem (e.g., frameworks like Django, Flask, or FastAPI) is a given. Strong experience with system design, data structures, algorithms, and software architecture principles is essential. Familiarity with cloud platforms (AWS, GCP, Azure), containerization technologies like Docker and Kubernetes, and infrastructure-as-code is highly common. A deep understanding of databases, both SQL (e.g., PostgreSQL) and NoSQL, is required. Beyond technical prowess, successful candidates demonstrate excellent problem-solving abilities, a product-oriented mindset, and strong communication skills to articulate complex concepts to diverse stakeholders. They exhibit a high degree of ownership, from initial concept through to deployment and maintenance. While requirements vary, most positions seek individuals with 5+ years of relevant experience, a proven track record of delivering complex systems, and a commitment to continuous learning and mentoring junior team members. Exploring Senior Python Engineer jobs opens doors to roles where technical leadership directly impacts product innovation and technological advancement.