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Principal Engineer - AI/ML Jobs (Remote work)

254 Job Offers

Principal Software Development Engineer
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Join our core team in Warsaw as a Principal Software Development Engineer. You will research, prototype, and optimize ML algorithms for GPU deployment, focusing on graphics and quantization. We seek an expert in Python/PyTorch, C/C++, and ML pipelines, passionate about cutting-edge hardware. Coll...
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Poland , Warsaw
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Not provided
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AMD
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Principal Software Engineering Manager
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Lead a critical SRE and Software Engineering team at Microsoft, building and operating the global-scale Substrate cloud platform for M365. This Redmond-based role requires deep technical expertise, security clearance eligibility, and a focus on reliability and compliance. Drive technical strategy...
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United States , Redmond
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Principal Software Engineer
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Join Microsoft's Customer Experience Engineering team as a Principal Software Engineer. This hands-on role involves working directly with strategic Azure customers and contributing to a core observability service. You'll need 6+ years of coding experience in languages like C# or Python and a back...
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United States , Multiple Locations
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Senior Software Engineer / Principal Software Engineer
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Join Microsoft's 365 team as a Senior or Principal Software Engineer. This remote role involves designing and building large-scale, high-performance cloud services like Exchange and Teams. We seek experts with 5+ years in backend development using C++, C#, or Java. Help shape the world's largest ...
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Costa Rica , Multiple Locations
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Not provided
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Microsoft Corporation
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Principal Process Safety / Functional Safety Engineer
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Lead process safety initiatives for a UK-based manufacturing leader. Facilitate key hazard studies (PHA/HAZOP/LOPA) and drive functional safety (SIL/SIS) in projects. Requires a Chemical Engineering degree, CFSE/TUV qualification, and strong risk assessment expertise. Enhance safety performance a...
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United Kingdom
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Not provided
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SRG
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Principal Site Reliability Engineer
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Lead reliability strategy as a Principal SRE at Arcadia, ensuring scalable, secure healthcare data platforms. You'll need 8+ years of SRE expertise, deep Kubernetes, Argo CD, Crossplane, and AWS proficiency. Drive incident response, define SLOs, and architect automation to reduce operational burd...
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The Muse
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Principal .NET Engineer
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Lead the architecture of a modern cloud-based HR SaaS platform as a Principal .NET Engineer. This remote role requires expert-level .NET Core, Azure, and microservices skills. You will drive technical excellence, mentor engineers, and explore AI tools while enjoying a flexible schedule and contin...
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Sigma Software Group
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Principal Software Engineer
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Join a rapidly growing AI startup as a Principal Software Engineer. Design and deliver production-grade systems where intelligent agents operate at scale. We seek 10+ years of backend expertise (Python/Go) and hands-on AI agent experience. Enjoy a fully remote role in the UK with competitive pay ...
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United Kingdom
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150000.00 - 200000.00 GBP / Year
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Oho Group Ltd
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Senior Principal Systems Design / Architecture Engineer
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Lead the architecture for complex systems in a key remote role at NTT DATA. This senior position requires deep expertise in system design, cloud platforms (Azure/AWS), and SDLCs within large-scale organizations. You will provide technical leadership, ensure strategic alignment, and drive impactfu...
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United States of America , Remote
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Not provided
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NTT DATA
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It principal network engineer
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Lead strategic network design and standards as a Principal Engineer. This senior role requires 10+ years of Cisco Route/Switch/Wireless expertise and datacenter design. You will develop technical roadmaps and ensure robust WAN infrastructure in Englewood, supported by comprehensive benefits.
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United States , Englewood
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52.15 - 77.58 USD / Hour
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American Nursing Care
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Principal Presales, Systems Engineer
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Lead HPE's AI-driven networking solutions as a Principal Presales Systems Engineer. This remote US role requires 15+ years of pre-sales expertise in routing, switching, Wi-Fi, and security. You will architect technological roadmaps, develop competitive proposals, and lead proof-of-concept engagem...
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United States , All, Iowa
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194500.00 - 456500.00 USD / Year
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Hewlett Packard Enterprise
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Principal Software Engineer - Red Team
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Lead the development of AI-driven offensive security services at Microsoft. As a Principal Software Engineer, you'll build generative AI and agentic systems to automate red team engagements. Leverage your expertise in software engineering and attacker TTPs to create cutting-edge tools. This role ...
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United States , Multiple Locations
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Principal Platform Engineer
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Lead platform strategy and engineering decisions for a global UK-based unit. Utilize your expertise in AWS, Kubernetes, and microservices to modernize systems at scale. Enjoy a culture of deep technical investment, including funded certifications, while guiding teams on cutting-edge projects.
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United Kingdom
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90000.00 - 110000.00 GBP / Year
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Linux Recruit
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Senior Principal Software Engineer
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Lead the modernization of critical healthcare applications as a Senior Principal Software Engineer. This hands-on technical role requires deep .NET, SQL Server, and legacy system expertise to drive architecture and unblock teams. Enjoy a remote-first culture with comprehensive benefits while shap...
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United States
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138568.00 - 221709.00 USD / Year
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One Call
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Principal AI Operations Engineer
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Lead AI Operations for Microsoft's security platform, ensuring reliability at massive scale. Design and architect deployment systems, CI/CD pipelines, and Kubernetes infrastructure. Drive operational excellence with 6+ years in SRE/DevOps and expert Kubernetes production experience. This role off...
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United States , Multiple Locations
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Principal Engineer, Tableflow
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Lead the technical strategy and architecture for Confluent's Tableflow as a Principal Engineer. You will design scalable, multi-tenant systems for large-scale data materialization and metadata management. This remote US role requires deep expertise in distributed storage, cloud-native platforms, ...
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United States
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274500.00 - 329400.00 USD / Year
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Confluent
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Principal Software Engineer
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United States , Multiple Locations
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Principal PreSales Systems Engineer - HPE Networking
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Join HPE Networking as a Principal PreSales Systems Engineer in Raleigh. Leverage your 5+ years of infrastructure engineering and deep expertise in Aruba/Juniper networking to design complex solutions. You will provide technical sales support, deliver compelling presentations, and build key custo...
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United States of America , Raleigh
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175000.00 - 411500.00 USD / Year
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Hewlett Packard Enterprise
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Principal Software Engineer - Azure Blob Storage
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Lead the development of AI-native storage as a Principal Software Engineer on Azure Blob Storage. Design next-generation distributed systems optimized for massive-scale AI/ML workloads, focusing on scalability and performance. Provide technical leadership and collaborate with cross-functional tea...
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United States , Multiple Locations
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Senior Principal Data Engineer
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Lead data architecture and engineering for a national railroad leader. This senior role requires 7+ years' experience with Informatica, AWS, and master data management (MDM). You will design end-to-end data solutions in Washington, D.C., driving innovation across key business departments.
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United States , Washington
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Salary
175427.00 - 215100.00 USD / Year
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AMTRAK
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About the Principal Engineer - AI/ML role

Embark on a leadership career at the pinnacle of technical innovation by exploring Principal Engineer - AI/ML jobs. A Principal Engineer in Artificial Intelligence and Machine Learning is a strategic visionary and a technical master, responsible for setting the technological direction for an organization's most ambitious AI initiatives. This is not an individual contributor role in the traditional sense; it is a force multiplier, blending deep hands-on expertise with architectural oversight, mentorship, and cross-functional leadership to transform complex business problems into scalable, intelligent solutions powered by AI.

Professionals in these senior roles typically bear a comprehensive set of responsibilities. They lead the architectural design and long-term strategy for AI/ML systems, ensuring they are robust, scalable, and aligned with business objectives. A key part of their duties involves conducting research and development to evaluate and integrate state-of-the-art algorithms and models, pushing the boundaries of what is technically possible. They provide technical leadership and mentorship to engineering teams, elevating the entire organization's capabilities through code reviews, best practice dissemination, and setting high standards for quality and innovation. Principal Engineers are also crucial in driving the entire machine learning lifecycle, from data acquisition and pipeline creation to model training, deployment, monitoring, and continuous iteration in production environments. They act as a bridge, communicating complex technical concepts to non-technical stakeholders and collaborating with product managers, data scientists, and business leaders to ensure successful project outcomes. Furthermore, they are often tasked with establishing technical governance, making critical stack and tooling decisions, and identifying and mitigating technical risks.

To qualify for Principal Engineer - AI/ML jobs, candidates must possess a formidable combination of education, experience, and skills. Typically, a Master's or Ph.D. in Computer Science, Statistics, or a related field is expected, coupled with 10+ years of progressive software engineering experience, with a significant portion dedicated to AI/ML. A deep, practical understanding of machine learning frameworks like TensorFlow or PyTorch is essential, as is proficiency in programming languages such as Python, Java, or Scala. Expertise in cloud platforms (AWS, GCP, Azure) and MLOps practices for automating the ML lifecycle is a standard requirement. Beyond technical prowess, successful candidates demonstrate exceptional leadership, strategic thinking, and communication skills. They have a proven track record of architecting and delivering complex, large-scale AI systems into production and possess the ability to mentor senior engineers and influence technical strategy across an organization. If you are ready to shape the future of technology and lead from the front, discovering the right Principal Engineer - AI/ML jobs is your next critical step.