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Principal Engineer - AI/ML Jobs (Remote work)

252 Job Offers

Principal Presales System Engineer
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United States , Dallas-Fort Worth
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175000.00 - 411500.00 USD / Year
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Hewlett Packard Enterprise
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Principal Full-Stack Engineer
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Poland , Warsaw
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Not provided
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Sigma Software Group
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Principal Software Engineering Lead - Xbox
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Join Xbox to lead GPU emulation for game preservation. As Principal Software Engineering Lead, you'll drive architectural vision, solve rendering challenges, and ensure compatibility across devices. Requires 6+ years in C/C++ and GPU expertise. Lead a team shaping the future of gaming in the US.
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United States , Multiple Locations
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Principal Software Engineer
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Principal Software Engineer role in Sydney, Australia. Join a cross-functional team building innovative solutions with modern cloud technologies and languages like C#, Java, or Python. Lead design, mentor engineers, and collaborate with strategic customers and Microsoft product teams. Competitive...
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Australia , Sydney
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Not provided
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Microsoft Corporation
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Principal Data Engineer
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Principal Data Engineer role leading next-gen data platform development. Build scalable, intelligent systems using Python, SQL, and cloud environments (Azure, AWS, GCP). Drive real-time services and insights with Kafka, data orchestration, and AI automation. Remote-friendly in South Africa, UK, o...
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South Africa; United Kingdom; Poland
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Not provided
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Dotdigital
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Principal Software Engineer - ISE
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Principal Software Engineer role in London with Microsoft’s ISE team. You’ll co-develop cloud-based AI solutions alongside enterprise customers, using C#, Python, or Java. Requires consultative experience, cross-functional collaboration, and up to 25% travel. Enjoy a competitive benefits package ...
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United Kingdom , London
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Not provided
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Microsoft Corporation
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Principal Software Engineer
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Lead the development of critical monitoring and alerting for Microsoft 365 Resilience, including Copilot. As a Principal Software Engineer, you will architect robust reliability measures like Graceful Degradation across core platforms. Requires a BS in CS with 12+ years coding in C, C++, C#, or P...
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United States , Multiple Locations
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Principal Software Engineer
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Principal Software Engineer at Microsoft Azure Data in Tokyo, Japan. Design and implement core PostgreSQL features, including planner, executor, and replication. Requires 6+ years of C/C++/C#/Java/Python experience and deep database internals knowledge. Join a world-class team building the data p...
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Japan , Tokyo
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Microsoft Corporation
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Principal Software Engineering Architect
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Join Microsoft’s Azure Resource Graph team as a Principal Software Engineering Architect. Lead the evolution of big data, LLM, and agentic platforms, designing scalable distributed systems. Requires 8+ years in C, C++, C#, Java, JavaScript, or Python. Drive AI adoption and build high-performance ...
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United States , Multiple Locations
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163000.00 - 296400.00 USD / Year
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Microsoft Corporation
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Staff / Principal Machine Learning Engineer, Serving
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Inworld AI seeks a Staff/Principal Machine Learning Engineer to lead inference optimization for realtime multimodal models in Switzerland. You will drive model acceleration using quantization, speculative decoding, and frameworks like vLLM or TRT-LLM. Expertise in C++, CUDA, and distributed syste...
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Switzerland
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Inworld AI
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Principal Software Engineering Manager
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Lead the engineering of Azure Storage’s foundational distributed file system as a Principal Software Engineering Manager. This role requires deep expertise in C/C++ and large-scale systems, with a focus on architecting solutions for Microsoft’s cloud. You will drive product strategy, mentor a col...
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United States , Multiple Locations
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139900.00 - 304200.00 USD / Year
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Microsoft Corporation
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Principal Software Engineer - CoreAI
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Lead the future of AI-powered software testing as a Principal Software Engineer on Microsoft's Playwright team. Design and implement AI-native capabilities for the core automation framework, integrating with GitHub and VS Code. This Redmond-based role requires deep expertise in AI/LLM models, bro...
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United States , Redmond
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Principal Software Engineer
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Lead the development of Azure's foundational storage service, impacting billions globally. This principal role requires 10+ years of experience in C/C++/C# and distributed systems. Drive high-impact projects, mentor teams, and shape the future of hyperscale cloud storage from India.
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India , Multiple Locations
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Microsoft Corporation
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Principal Site Reliability Engineer
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Lead critical incident response and drive reliability standards for Microsoft's M365 Substrate Core services. This principal SRE role requires 7+ years of technical experience and expertise in incident command and operational governance. You will ensure high-quality handling of severe outages, mi...
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United States , Multiple Locations
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Principal Security Engineer
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Join Microsoft's Windows Security team in Redmond as a Principal Security Engineer. You will conduct offensive security, design reviews, and penetration testing to protect billions of Windows users. This hands-on role requires deep expertise in OS security, vulnerability research, and driving sys...
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United States , Redmond
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163000.00 - 296400.00 USD / Year
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Microsoft Corporation
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Principal Software Engineer
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Join Microsoft's global Industry Solutions Engineering team in Redmond. As a Principal Software Engineer, you'll solve complex customer challenges using cloud technologies like C#, Java, or Python. Lead design, mentor engineers, and innovate directly with clients. Requires a technical degree and ...
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United States , Redmond
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Sr Principal Product Security Engineer
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Lead product security for life-saving medical technology as a Sr. Principal Engineer. You will define security architecture, conduct threat modeling, and embed security across the full software lifecycle. This role requires 8+ years in SSDLC and expertise in regulated environments. Join a mission...
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United States , Skaneateles Falls
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112000.00 - 154000.00 USD / Year
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Baxter
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Principal SWE Manager - Data Engineering
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Lead GitHub's data engineering strategy as a Principal SWE Manager. You'll design scalable data pipelines and robust models using languages like Python or Go. This role requires 5+ years of leadership and expertise in architecture, based in the Czech Republic. Shape the future of data platforms a...
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Czech Republic , Multiple Locations
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Not provided
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Microsoft Corporation
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Principal Software Development Engineer
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Lead the architecture of next-generation digital healthcare platforms as a Principal Full-Stack Engineer. This senior role requires 12+ years' experience designing scalable, API-first systems and integrating AI/GenAI. You will set technical direction, mentor teams, and build secure solutions usin...
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United States
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144200.00 - 288400.00 USD / Year
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CVS Health
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Principal Engineer Software, Dev Infrastructure
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Lead the development of a cutting-edge, cloud-native infrastructure platform in San Francisco. As a Principal Engineer, you will architect scalable developer tooling, CI/CD, and deployment systems using technologies like Kubernetes and Terraform. Your deep systems expertise will drive velocity an...
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United States , San Francisco
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147000.00 - 237500.00 USD / Year
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Palo Alto Networks
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About the Principal Engineer - AI/ML role

Embark on a leadership career at the pinnacle of technical innovation by exploring Principal Engineer - AI/ML jobs. A Principal Engineer in Artificial Intelligence and Machine Learning is a strategic visionary and a technical master, responsible for setting the technological direction for an organization's most ambitious AI initiatives. This is not an individual contributor role in the traditional sense; it is a force multiplier, blending deep hands-on expertise with architectural oversight, mentorship, and cross-functional leadership to transform complex business problems into scalable, intelligent solutions powered by AI.

Professionals in these senior roles typically bear a comprehensive set of responsibilities. They lead the architectural design and long-term strategy for AI/ML systems, ensuring they are robust, scalable, and aligned with business objectives. A key part of their duties involves conducting research and development to evaluate and integrate state-of-the-art algorithms and models, pushing the boundaries of what is technically possible. They provide technical leadership and mentorship to engineering teams, elevating the entire organization's capabilities through code reviews, best practice dissemination, and setting high standards for quality and innovation. Principal Engineers are also crucial in driving the entire machine learning lifecycle, from data acquisition and pipeline creation to model training, deployment, monitoring, and continuous iteration in production environments. They act as a bridge, communicating complex technical concepts to non-technical stakeholders and collaborating with product managers, data scientists, and business leaders to ensure successful project outcomes. Furthermore, they are often tasked with establishing technical governance, making critical stack and tooling decisions, and identifying and mitigating technical risks.

To qualify for Principal Engineer - AI/ML jobs, candidates must possess a formidable combination of education, experience, and skills. Typically, a Master's or Ph.D. in Computer Science, Statistics, or a related field is expected, coupled with 10+ years of progressive software engineering experience, with a significant portion dedicated to AI/ML. A deep, practical understanding of machine learning frameworks like TensorFlow or PyTorch is essential, as is proficiency in programming languages such as Python, Java, or Scala. Expertise in cloud platforms (AWS, GCP, Azure) and MLOps practices for automating the ML lifecycle is a standard requirement. Beyond technical prowess, successful candidates demonstrate exceptional leadership, strategic thinking, and communication skills. They have a proven track record of architecting and delivering complex, large-scale AI systems into production and possess the ability to mentor senior engineers and influence technical strategy across an organization. If you are ready to shape the future of technology and lead from the front, discovering the right Principal Engineer - AI/ML jobs is your next critical step.