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Sr Program Manager Jobs

57 Job Offers

Sr. Program Manager
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Lead cross-functional R&D programs to develop groundbreaking life science products at 10x Genomics in Pleasanton. This senior role requires 5+ years in life science product development, expertise in managing from research to launch, and proficiency with advanced AI tools. Enjoy equity, comprehens...
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United States , Pleasanton
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151100.00 - 204500.00 USD / Year
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10x Genomics
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Sr. Manager - Program Execution
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Lead the core engineering execution for advanced robotics and automation programs at GM. This senior leadership role requires 10+ years of experience in complex electro-mechanical systems, from concept to launch. You will drive technical execution, schedule integrity, and cross-functional alignme...
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United States , Warren
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Not provided
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General Motors
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Sr. Program Manager, Tech
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United States , Sunnyvale
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183900.00 - 204000.00 USD / Year
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Uber
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Sr. Program Manager
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United States , Overland Park
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83100.00 - 149900.00 USD / Year
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T-Mobile
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Sr. Program Manager
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United States , Overland Park
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83100.00 - 149900.00 USD / Year
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T-Mobile
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Sr. Learning & Development Program Manager
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United States , Secaucus
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Not provided
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Sanmina
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Sr. Mechanical Program Manager
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United States , Cheyenne, WY
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Not provided
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JLL
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Sr. Staff Program Manager - Emerging Markets
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United Kingdom
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Not provided
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ALSO
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Sr. Technical Program Manager - Opportunity Analytics
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Lead data-driven growth as a Senior Technical Program Manager in New York. Analyze large-scale monetization data with SQL, Python, and PowerBI to identify global advertising opportunities. Partner with cross-functional teams to turn insights into actionable strategies for Microsoft Advertising.
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United States , New York
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119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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Sr Program Manager, Global Escalations
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Drive large-scale impact as a Senior Program Manager for Global Escalations at Uber. You will build strategy, implement programs, and improve processes to enhance customer experience across all business lines. This role requires 4+ years in program management, data-driven decision-making, and cro...
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United States , New York; Phoenix; Chicago; San Francisco
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105000.00 - 145500.00 USD / Year
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Uber
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Sr. Supply Chain Program Manager
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Lead supply planning for Microsoft's global cloud and AI infrastructure in Redmond. Develop and optimize the Supply Plan of Record (SPOR) using advanced scenario modeling. Requires a Bachelor's degree and 3+ years in supply chain, operations, or planning. Master's degree and cloud/high-tech exper...
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United States , Redmond
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96500.00 - 188400.00 USD / Year
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Microsoft Corporation
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Sr Technical Program Manager - Selection & Fulfillment
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United States , New York
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180000.00 - 200000.00 USD / Year
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Uber
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Sr Technical Program Manager - Selection & Fulfillment
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United States , New York
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180000.00 - 200000.00 USD / Year
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Uber
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Sr. Technical Program Manager
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India , Bengaluru
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Not provided
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Zuora
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Sr Program Manager Tech - Gen AI
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Lead AI program delivery and client engagement for coding, agentic AI, and data analytics at Uber AI Solutions. Leverage 7+ years in software/ML engineering and client-facing leadership to shape projects and drive innovation. This senior role in Sunnyvale, SF, or NYC offers bonus and equity eligi...
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United States , Sunnyvale; San Francisco; New York
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167000.00 - 185500.00 USD / Year
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Uber
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Sr. Program Manager, AI Data Operations
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Lead large-scale AI data annotation programs for LLM training at Uber's AI Solutions. Utilize your 7+ years in ML ops or data labeling to define scalable workflows and manage global vendor operations. This senior role in San Francisco/Sunnyvale is pivotal for building the data foundry powering ne...
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United States , San Francisco; Sunnyvale
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167000.00 - 185500.00 USD / Year
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Uber
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Sr. Program Manager - Agentic AI for Azure Supportability
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Join Azure EngOps as a Senior Program Manager for Agentic AI. You will define the AI roadmap to enhance Azure supportability, driving efficiency and customer impact. This role requires 4+ years in technical program management and 2+ years in AI/ML. Collaborate with global teams in Redmond to buil...
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United States , Redmond
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119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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Sr Technical Program Manager, Rider Mobility
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Lead strategic platform initiatives as a Senior Technical Program Manager for Uber's Rider Mobility team in Seattle or San Francisco. You will drive large-scale, cross-functional engineering projects to enhance integration capabilities across Uber's ecosystem. The role requires 8+ years of experi...
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United States , Seattle; San Francisco
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180000.00 - 200000.00 USD / Year
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Uber
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Sr. Research Program Manager
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Join Meta Technologies as a Senior Research Program Manager in Palo Alto. Drive strategic programs and shape operational hygiene for the Research function. We seek an organized project management expert with 8+ years' experience, adept at stakeholder influence and multi-tasking. Enjoy top-tier be...
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United States , Palo Alto
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70.00 - 74.00 USD / Hour
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Apex Systems
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Sr Staff Program Manager- AI Strategy & Governance Lead, Finance Technology
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Lead AI Strategy & Governance for Finance Technology in San Francisco. Develop and drive the AI roadmap to transform FP&A, accounting, and compliance. Requires strategic finance experience, exceptional communication skills, and a passion for applying Gen AI. This pivotal role offers competitive c...
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United States , San Francisco
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Salary
212000.00 - 235500.00 USD / Year
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Uber
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About the Sr Program Manager role

Sr Program Manager Jobs represent a senior-level leadership role focused on orchestrating complex, cross-functional initiatives from conception through execution. Professionals in this position are responsible for the strategic oversight and operational delivery of large-scale programs that span multiple teams, departments, and often external partners. Unlike project managers who handle individual projects, Sr Program Managers manage a portfolio of interconnected projects, ensuring alignment with broader organizational goals, timelines, and budgets.

The core of this profession involves developing and maintaining master program plans, defining milestones, and mapping critical dependencies across various workstreams. Sr Program Managers are the central hub for communication, translating technical requirements into business impact for executive stakeholders and ensuring that all teams—from engineering and product development to supply chain and marketing—remain synchronized. A significant part of the role is proactive risk management: identifying potential bottlenecks, resource contention, or technical roadblocks early, and driving mitigation strategies to keep programs on track. This requires exceptional problem-solving skills and the ability to make independent, strategic judgments under pressure.

Typical responsibilities include establishing key performance indicators (KPIs) to measure program health and profitability, designing reporting dashboards for real-time visibility, and leading regular steering committee meetings with senior leadership. Sr Program Managers also drive process improvement, creating repeatable templates and playbooks that enable the organization to scale its program delivery without proportional increases in headcount. Change management is another critical component, as these leaders guide teams through new processes, tools, or strategic shifts to ensure sustained adoption and execution.

To succeed in Sr Program Manager jobs, candidates need a combination of deep program management expertise and domain fluency. Common requirements include a bachelor’s degree in a relevant field (such as business, engineering, or computer science), along with 5-10 years of progressive experience in program management, product development, operations, or a related area. Technical acumen is essential—whether understanding AI/ML development cycles, semiconductor design processes, or manufacturing automation—to effectively communicate with engineers and technical leads. Strong leadership and negotiation skills are a must, as the role involves influencing without direct authority across multiple teams. Proficiency with project management tools (like Jira or Asana), budget oversight, vendor management, and executive presentation skills are also standard expectations. Many roles prefer or require certifications such as PMP (Project Management Professional) or Agile certifications. Ultimately, these jobs are ideal for strategic thinkers who thrive on complexity, love bringing order to chaos, and are driven by the challenge of delivering high-impact results through cross-team collaboration.