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Sr. Engineer United States Jobs (Remote work)

68 Job Offers

ML Engineer Sr
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Seeking a Senior ML Engineer to deploy and monitor production machine learning models in the United States. This role requires 5+ years of experience, advanced Python proficiency, and expertise in ML libraries and SQL. You will transform prototypes into robust tools, ensure model accuracy, and re...
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United States
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59.00 - 88.50 USD / Hour
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Advocate Health Care
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Sr. Backend Engineer - Tech Lead (Java)
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Lead our backend technical vision as a Sr. Java Tech Lead. You'll architect and enhance Java 17+ Spring Boot microservices, ensuring robust performance and mentorship. This US-based role offers equity, bonus, and comprehensive benefits for a seasoned engineer with 8+ years of deep Java and relati...
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United States
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200000.00 - 220000.00 USD / Year
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Real Broker, LLC
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Sr. AI/Automation Engineer - HR Technology
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Seeking a Senior AI/Automation Engineer for HR Technology. Design and build intelligent plugins and automations on platforms like Moveworks and Serval, integrating with Workday and ServiceNow. Requires 6+ years on HR platforms, back-end development expertise, and strong API integration skills. En...
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United States
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107600.00 - 132150.00 USD / Year
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General Motors
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Sr Big Data Engineer - Oozie and Pig (GCP)
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United States
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Not provided
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Rackspace
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IT Sr Implementation Engineer
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United States , Englewood
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49.78 - 74.05 USD / Hour
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American Nursing Care
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IT Epic Willow Ambulatory Sr Software Engineer
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United States , Englewood
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49.78 - 74.05 USD / Hour
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American Nursing Care
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Sr. Full Stack Engineer (Python)
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United States , Remote in Atlanta, GA; Remote in Austin, TX; Remote in Charlotte, NC; Remote in Chicago, IL; Remote in Dallas, TX; Remote in Minneapolis, MN; Remote in Phoenix, AZ; Remote in Syracuse, NY
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112000.00 - 169000.00 USD / Year
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Terakeet
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Sr. Full Stack Engineer (Python)
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United States , Atlanta; Austin; Charlotte; Chicago; Dallas; Minneapolis; Phoenix; Syracuse
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112000.00 - 169000.00 USD / Year
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Terakeet
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Sr. Software Engineer
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Join us as a Senior Site Reliability Engineer to safeguard our production systems' reliability and performance. You will own incident response, enhance observability, and drive automation using Ruby, AWS, and AI tools. This remote US role offers competitive compensation and benefits while you bui...
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United States
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Not provided
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Bamboo Health
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Sr Software Engineer
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United States
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119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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Sr. Staff Software Engineer - Hue
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Lead the technical strategy for Hue, Cloudera's open-source SQL Assistant, as a Senior Staff Software Engineer. You will architect a secure, scalable platform for enterprise analytics, driving AI integration and core feature development. This remote US role requires strong Python, web framework (...
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United States , Austin; Remote
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Not provided
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Cloudera
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Sr. Digital Development Engineer
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Seeking a Senior Digital Development Engineer in Buffalo Grove to design and develop enterprise healthcare applications. This role requires a Master's degree and 4+ years of expertise in CI/CD, Angular, JavaScript, and Agile methodologies within a DevOps environment. We offer comprehensive benefi...
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United States , Buffalo Grove
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148949.00 - 240000.00 USD / Year
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CVS Health
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Sr Software Development Engineer
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Join CVS Health as a Senior Software Development Engineer in Woonsocket, RI. Design and build innovative iOS applications using Swift, SwiftUI, and RESTful APIs within an Agile/CI/CD environment. This role offers comprehensive benefits, including medical/dental/vision, 401(k), and PTO, while tran...
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United States , Woonsocket, RI
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109512.00 - 180000.00 USD / Year
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CVS Health
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Sr. Cloud Engineer
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Seeking a Senior Cloud Engineer in Woonsocket to design enterprise applications for CVS Health. This role requires 5+ years with cloud platforms (Azure/AWS/GCP), SQL/SAS, and large-scale healthcare data. You'll develop solutions, mentor junior staff, and enjoy robust benefits including equity, we...
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United States , Woonsocket
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147680.00 - 180000.00 USD / Year
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CVS Health
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Sr Software Development Engineer
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Join CVS Health as a Senior Software Development Engineer in Woonsocket. Design and develop digital platforms using Java, Spring Boot, and microservices within Agile/SAFe frameworks. This role requires expertise in CI/CD, REST APIs, and full lifecycle development to transform healthcare. We offer...
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United States , Woonsocket
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110406.00 - 162000.00 USD / Year
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CVS Health
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Sr. Staff Software Engineer - Hue
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Lead the technical strategy for Hue, Cloudera's open-source SQL Assistant, as a Senior Staff Software Engineer. You will architect its core features, drive its AI roadmap, and ensure enterprise-grade scalability and security. This remote US role requires strong Python and web framework expertise ...
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United States , Austin; Remote
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Not provided
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Cloudera
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Sr. Technical AI Enablement Engineer
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Join ModelOp as a Sr. Technical AI Enablement Engineer in Utah or Chicago. Drive AI governance implementation, translating strategy into scalable practice for enterprise clients. Leverage 10+ years of technical consulting experience with AI tools and regulations. Enjoy full benefits, including he...
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United States , Utah, Chicago
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ModelOp
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Sr. QA Engineer
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Seeking a Senior QA Engineer for a direct hire role in the United States. You will develop and integrate automation frameworks using WDIO, TypeScript, and Java for UI and API testing. Key tasks include working with Docker, Jenkins, Kafka, and validating services in a microservices architecture.
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United States
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43.00 USD / Hour
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SAR Tech
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Sr. Full-Stack Engineer, Product
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Join Zora's Product team as a Senior Full-Stack Engineer. Build scalable user experiences powering hundreds of millions in on-chain volume. You'll own features end-to-end across front-end (React/TypeScript), back-end (Node/GraphQL), and smart contracts. This remote role requires US time zone loca...
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United States
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175000.00 - 215000.00 USD / Year
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Zora
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Sr. Protocol Engineer, Product
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Join Zora's Trade team as a Senior Protocol Engineer. Design and implement core smart contracts for high-volume on-chain trading and creator markets. You'll need deep EVM expertise, 4+ years in DeFi, and a security-first mindset. Enjoy a remote-first culture, competitive compensation, and compreh...
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United States
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Salary
200000.00 - 300000.00 USD / Year
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Zora
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About the Sr. Engineer role

A Senior Engineer is a highly experienced technical professional who applies advanced engineering principles to design, develop, optimize, and maintain complex systems, products, or processes. Unlike entry-level roles, a Sr. Engineer is expected to operate with significant autonomy, taking ownership of technical deliverables, leading cross-functional projects, and mentoring junior team members. These roles are critical across industries such as biotechnology, pharmaceuticals, software, manufacturing, and energy, where reliability, efficiency, and innovation are paramount.

The core responsibilities of a Sr. Engineer vary by discipline but commonly include system ownership, lifecycle management, and performance optimization. In hardware and manufacturing contexts, this involves ensuring the reliability of critical equipment through preventive and predictive maintenance strategies, root cause analysis of failures, and implementation of corrective actions. A Sr. Engineer often defines maintenance strategies, manages spare parts inventory, and leads equipment improvement projects to enhance uptime and compliance with regulatory standards. In software and systems engineering, the role focuses on architecting scalable solutions, developing full software stacks, and integrating technologies like microservices, virtualization, and big data platforms. Regardless of the field, a Sr. Engineer is a key driver of structured problem-solving, using methodologies such as Failure Modes and Effects Analysis (FMEA), Design of Experiments (DOE), and root cause analysis to identify and mitigate risks.

Typical skills and requirements for Sr. Engineer jobs include a bachelor’s degree in engineering or a related field, with many positions requiring a master’s or doctorate. Experience levels generally range from 4 to 10 years of relevant work, depending on educational background. Technical expertise is essential, whether in mechanical design, software architecture, or bioprocess equipment. Beyond technical depth, a Sr. Engineer must demonstrate proficiency in data analysis, technical writing, and cross-functional collaboration. Strong communication skills are vital for translating complex technical findings into actionable insights for operations, quality, and management teams. Leadership ability is also a common requirement, as these professionals often supervise base-level engineers, mentor colleagues, and lead multi-functional teams to resolve system-level challenges.

In summary, Sr. Engineer jobs represent a career stage where professionals shift from executing tasks to owning outcomes. They are trusted to make high-impact decisions that affect product quality, system reliability, and operational efficiency. Whether optimizing a pharmaceutical manufacturing line, designing a robust drug delivery device, or building a resilient software platform, the Sr. Engineer is the technical backbone that ensures projects are delivered with excellence. This role offers a blend of hands-on technical work, strategic thinking, and mentorship, making it a pivotal position for driving innovation and maintaining competitive advantage in any engineering-driven organization.