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Sr. Engineer United States Jobs (Hybrid work)

134 Job Offers

Digital S/W Engineer Sr Mgr - Vice President
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Lead and innovate as a Digital S/W Engineer Sr Mgr - Vice President in Jacksonville, FL. This role requires 6-10 years of experience in Apps Development or Enterprise Architecture, with expertise in AWS, PCF, and Akamai. You will manage teams, drive cloud adoption, and mentor talent while enjoyin...
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125600.00 - 188400.00 USD / Year
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Citi
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Sr Principal Electrical Engineer
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Sr. Principal Electrical Engineer sought to lead innovative electrical design for Baxter’s medication delivery portfolio in Round Lake, IL. Requires a Bachelor’s in Electrical Engineering with 10+ years of experience in electromechanical hardware, embedded microcontrollers, and analog/digital des...
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128000.00 - 176000.00 USD / Year
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Baxter
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Sr Software Engineer
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Senior Software Engineer needed in New York to design, build, and deploy ML models for ranking and recommendation systems. Must have expertise in C++, Python, Java, deep learning (PyTorch/TensorFlow), and large-scale data processing with Spark. Master’s degree required. Solve complex production i...
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202000.00 - 246000.00 USD / Year
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Uber
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Sr Software Engineer, Core Security Engineering
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Uber seeks a Sr Software Engineer for Core Security Engineering in Seattle, San Francisco, or Sunnyvale. You will build secure-by-default production environments and industry-leading security products. Requires 6+ years in software engineering with Go, Java, or Python, plus experience in large-sc...
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United States, Seattle, WA, San Francisco, CA, Sunnyvale, CA
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202000.00 - 224000.00 USD / Year
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Uber
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Sr. Software Engineer - CTJ - Poly
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Join Microsoft Defender as a Sr. Software Engineer in Redmond, WA, building cutting-edge cloud security solutions for government environments. You’ll leverage C, C++, C#, or Python to deliver scalable, highly reliable services. Requires an active Top Secret/SCI clearance with Polygraph. Work on w...
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119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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Sr. Fellow Machine Learning Engineer
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Join a world-class team as a Sr. Fellow Machine Learning Engineer in San Jose, tackling distributed training of large generative AI models on AMD GPUs. You will optimize end-to-end pipelines, scale distributed systems, and contribute to open-source frameworks. Requires deep expertise in ML (PyTor...
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292000.00 - 438000.00 USD / Year
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AMD
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Sr. Software Engineer - Vehicle Order Fulfillment
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Sr. Software Engineer needed to modernize GM’s vehicle order fulfillment systems. You will lead design and delivery of enterprise-scale Java, React, and Quarkus solutions, driving CI/CD and microservices architecture. Requires 7+ years Java experience, mentoring skills, and expertise in React, RE...
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General Motors
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Sr. Automation Engineer
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Sr. Automation Engineer sought to lead supplier automation assessments and manufacturing optimization in Warren, US. This role drives strategic initiatives in material handling and flow, requiring 5+ years of experience and strong analytical skills in Power BI. You will influence cross-functional...
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General Motors
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Sr Staff Engineer - Core Infrastructure
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Uber seeks a visionary Sr Staff Engineer to architect the future of its Core Infrastructure Platform. You will lead technical strategy for massive-scale systems handling 1M+ concurrent trips, driving fleet utilization and scaling GPU clusters for Generative AI. This role demands 12+ years of expe...
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United States, New York, Seattle, San Francisco, Sunnyvale
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267000.00 - 297000.00 USD / Year
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Uber
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Sr. Software Engineer -CTJ- Poly
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Senior Software Engineer needed for Microsoft’s Power Platform team in Redmond, WA. You will build and operate Power Automate services within Air-Gapped and Sovereign Cloud environments, blending software engineering with SRE. Requires a Top Secret/SCI clearance with polygraph and 4+ years coding...
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119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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Sr. Systems Engineer / Integrator
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Seeking a Sr. Systems Engineer / Integrator in Linthicum, MD (Hybrid) to lead technical integration and information sharing initiatives. Requires an active TS/SCI clearance, a Master’s degree with 10+ years of experience, and expertise in AWS, Hadoop, Spark, and system integration. Ideal candidat...
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Assurit
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Sr Staff Engineer Software (Prisma AIRS - Runtime BackEnd)
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Senior Staff Software Engineer (BackEnd) for Prisma AIRS Runtime Security in Santa Clara, CA. Drive the future of AI security by architecting scalable distributed systems using Python/Golang, Kubernetes, and GCP. Lead cross-functional teams, mentor engineers, and deliver cutting-edge runtime secu...
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126000.00 - 204500.00 USD / Year
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Palo Alto Networks
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Sr Site Reliability Engineer, Secure Federal Operations
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Seeking a Senior Site Reliability Engineer for secure federal operations in Herndon, VA. Design scalable, reliable solutions across Azure, AWS, and M365, leveraging DevSecOps and IaC. Requires expertise in Active Directory, certificate lifecycle, and network security. Enjoy a competitive salary, ...
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107300.00 - 193500.00 USD / Year
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T-Mobile
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Device Engineering Sr. Engineer
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Join Amgen as a Device Engineering Sr. Engineer in Cambridge, MA, and drive innovation in medical device design. Leverage your expertise in Design for Robustness disciplines like Kinematic and Tolerance Design to enhance Class II/III devices. Collaborate on cross-functional teams to improve syste...
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115494.60 - 156257.40 USD / Year
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Amgen
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About the Sr. Engineer role

A Senior Engineer is a highly experienced technical professional who applies advanced engineering principles to design, develop, optimize, and maintain complex systems, products, or processes. Unlike entry-level roles, a Sr. Engineer is expected to operate with significant autonomy, taking ownership of technical deliverables, leading cross-functional projects, and mentoring junior team members. These roles are critical across industries such as biotechnology, pharmaceuticals, software, manufacturing, and energy, where reliability, efficiency, and innovation are paramount.

The core responsibilities of a Sr. Engineer vary by discipline but commonly include system ownership, lifecycle management, and performance optimization. In hardware and manufacturing contexts, this involves ensuring the reliability of critical equipment through preventive and predictive maintenance strategies, root cause analysis of failures, and implementation of corrective actions. A Sr. Engineer often defines maintenance strategies, manages spare parts inventory, and leads equipment improvement projects to enhance uptime and compliance with regulatory standards. In software and systems engineering, the role focuses on architecting scalable solutions, developing full software stacks, and integrating technologies like microservices, virtualization, and big data platforms. Regardless of the field, a Sr. Engineer is a key driver of structured problem-solving, using methodologies such as Failure Modes and Effects Analysis (FMEA), Design of Experiments (DOE), and root cause analysis to identify and mitigate risks.

Typical skills and requirements for Sr. Engineer jobs include a bachelor’s degree in engineering or a related field, with many positions requiring a master’s or doctorate. Experience levels generally range from 4 to 10 years of relevant work, depending on educational background. Technical expertise is essential, whether in mechanical design, software architecture, or bioprocess equipment. Beyond technical depth, a Sr. Engineer must demonstrate proficiency in data analysis, technical writing, and cross-functional collaboration. Strong communication skills are vital for translating complex technical findings into actionable insights for operations, quality, and management teams. Leadership ability is also a common requirement, as these professionals often supervise base-level engineers, mentor colleagues, and lead multi-functional teams to resolve system-level challenges.

In summary, Sr. Engineer jobs represent a career stage where professionals shift from executing tasks to owning outcomes. They are trusted to make high-impact decisions that affect product quality, system reliability, and operational efficiency. Whether optimizing a pharmaceutical manufacturing line, designing a robust drug delivery device, or building a resilient software platform, the Sr. Engineer is the technical backbone that ensures projects are delivered with excellence. This role offers a blend of hands-on technical work, strategic thinking, and mentorship, making it a pivotal position for driving innovation and maintaining competitive advantage in any engineering-driven organization.