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Sr Principal Engineer Jobs

36 Job Offers

Sr Principal Engineer - Software Quality
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Sr Principal Engineer - Software Quality role in Gloucester, UK, leading compliance for life-saving medical devices. Requires 10+ years in software quality engineering with expertise in ISO 13485, EU MDR, and IEC 62304. Drive Agile integration with regulatory frameworks, managing design controls ...
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Baxter
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Sr. Principal Engineer Software (Unit 42)
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Join Palo Alto Networks as a Sr. Principal Engineer in Connecticut, building AI-driven tools for Unit 42’s threat research team. Leverage Python, SQL, and containerization (Docker, Kubernetes) to design intelligent data architectures and automate workflows. Ideal for experts in modern AI, REST AP...
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Location
United States, Connecticut
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Salary
126000.00 - 204500.00 USD / Year
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Palo Alto Networks
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Sr. Principal Systems Engineer
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Sr. Principal Systems Engineer sought in Milwaukee to lead technical roadmaps for life-saving medical devices. Leverage 8+ years of engineering experience and expertise in ISO 14971 & IEC 60601 within an Agile SAFe framework. Drive innovation by translating market needs into system requirements, ...
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128000.00 - 176000.00 USD / Year
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Baxter
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Sr Principal / Architect Engineer Software (Cortex XSIAM)
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Seeking a Sr. Principal Architect to join the XSIAM engineering group in Tel Aviv, Israel. This product-facing role bridges engineering, product management, and customer success to drive scalable, innovative solutions. Requires 10+ years of software engineering experience, expertise in cloud-nati...
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Palo Alto Networks
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Sr Principal Engineer, Automation Projects
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Lead complex automation projects as a Sr Principal Engineer in Round Lake, IL. Requires a BS in Mechanical Engineering, 8+ years of experience, and proficiency in SolidWorks. Drive cross-functional teams to design automated manufacturing equipment, manage budgets, and ensure cGMP compliance. Enjo...
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128000.00 - 176000.00 USD / Year
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Baxter
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Sr Principal Engineer - Software Quality
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Sr. Principal Engineer - Software Quality role at Baxter in Gloucester, UK. Lead software quality for life-saving medical devices, ensuring compliance with ISO 13485, EU MDR, and FDA standards. Requires 10+ years in regulated software engineering, expertise in IEC 62304, and Agile integration. En...
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Salary
Not provided
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Baxter
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Sr. Principal Systems Engineer
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Seeking a Sr. Principal Systems Engineer in Skaneateles Falls, NY. Lead complex, cross-functional programs and drive technical strategy for medical devices. Requires a Bachelor's in Engineering, 8+ years of experience, and deep knowledge of ISO 14971 and IEC 62304. Benefits include medical/dental...
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Location
United States, Skaneateles Falls
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Salary
128000.00 - 176000.00 USD / Year
https://www.baxter.com/ Logo
Baxter
Expiration Date
Until further notice
Sr Principal Engineer - Software Quality
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Sr Principal Engineer - Software Quality role in Gloucester, UK, driving compliance for life-saving medical devices. Lead Agile integration with ISO 13485, IEC 62304, and EU MDR. Requires 10+ years in software quality engineering and deep FDA expertise. Enjoy benefits like professional developmen...
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Salary
Not provided
https://www.baxter.com/ Logo
Baxter
Expiration Date
Until further notice
Sr. Principal Systems Engineer
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Salary
128000.00 - 176000.00 USD / Year
https://www.baxter.com/ Logo
Baxter
Expiration Date
Until further notice
Sr. Principal Systems Engineer
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Lead system architecture and risk management for life-saving medical devices as a Sr. Principal Systems Engineer at Baxter in Skaneateles Falls, NY. Drive New Product Development and sustainment within the Front Line Care portfolio, leveraging deep expertise in ISO 14971 and IEC 62304. This role ...
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Location
United States, Skaneateles Falls
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Salary
128000.00 - 176000.00 USD / Year
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Baxter
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Sr Principal Electrical Engineer
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Senior Principal Electrical Engineer sought to lead innovative electrical design for medication delivery monitoring and sensing products in Round Lake, US. Requires a Bachelor’s in Electrical Engineering and 10+ years of experience in electromechanical hardware development, ideally in medical dev...
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128000.00 - 176000.00 USD / Year
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Baxter
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Sr Principal Site Reliability Engineer (Sovereign Cloud)
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Seeking a Sr Principal Site Reliability Engineer to lead Sovereign Cloud operations for Prisma Access in Sofia, Bulgaria. You will design intelligent automation, ensure high uptime for security SaaS products, and manage multi-cloud infrastructure at scale. Requires 10+ years in SRE/DevOps, deep G...
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Palo Alto Networks
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Sr Principal Site Reliability Engineer (Sovereign Cloud)
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Join Palo Alto Networks as a Sr Principal Site Reliability Engineer for Sovereign Cloud in Sofia, Bulgaria. Leverage 10+ years of DevOps and cloud-native expertise on GCP and AWS, mastering Terraform, Kubernetes, and GitOps. Design secure, scalable infrastructure, automate monitoring, and lead ro...
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Not provided
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Palo Alto Networks
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Sr Principal Electrical Engineer
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Sr. Principal Electrical Engineer sought to lead innovative electrical design for Baxter’s medication delivery portfolio in Round Lake, IL. Requires a Bachelor’s in Electrical Engineering with 10+ years of experience in electromechanical hardware, embedded microcontrollers, and analog/digital des...
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Salary
128000.00 - 176000.00 USD / Year
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Baxter
Expiration Date
Until further notice
Sr Principal Electrical Engineer
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Senior Principal Electrical Engineer sought to lead innovative electrical design for life-saving medication delivery and monitoring devices. This role demands 10+ years of experience in electromechanical hardware, embedded systems, and analog/digital circuit design. Based in Round Lake, IL, the p...
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Salary
128000.00 - 176000.00 USD / Year
https://www.baxter.com/ Logo
Baxter
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Principal / Sr Staff Software Engineer (ITDR)
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Principal Software Engineer (ITDR) sought to design and build cutting-edge, high-scale systems using Angular, React, and Python on AWS. Requires 7+ years of SW development, deep expertise in modern frameworks, and strong TypeScript/RxJS skills. Lead infrastructure design, implement sophisticated ...
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Location
Israel, Mulebbis
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Salary
Not provided
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Palo Alto Networks
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Until further notice

About the Sr Principal Engineer role

Sr. Principal Engineer jobs represent the pinnacle of individual technical contribution and leadership within the engineering domain. Professionals in these roles are not just senior engineers; they are recognized as industry experts, technical visionaries, and pivotal leaders who shape the technological future of their organizations. They operate at the intersection of deep technical mastery, strategic business acumen, and influential mentorship, driving innovation and solving the most complex, high-impact challenges.

Typically, a Sr. Principal Engineer is responsible for setting the long-term technical vision and architectural direction for critical systems and platforms. They lead the design and implementation of highly scalable, reliable, and performant solutions, often making foundational decisions that affect the entire product ecosystem. Their day-to-day activities involve architecting systems from the ground up, conducting deep technical reviews, and establishing engineering best practices and standards that elevate the entire organization's output. A core responsibility is to deconstruct ambiguous, large-scale problems into actionable technical roadmaps, guiding multiple teams towards a coherent and elegant solution.

Beyond hands-on architecture and coding, these roles carry significant leadership duties. Sr. Principal Engineers are expected to be force multipliers, actively mentoring senior engineers, principal engineers, and technical managers. They foster a culture of excellence, continuous learning, and rigorous engineering discipline. Their influence extends across departments; they frequently collaborate with executive leadership, product management, and other business units to align technical strategy with business goals, translating market needs into technical requirements. They are the go-to authorities for critical technical decisions, risk assessment, and troubleshooting systemic issues.

The typical skill set for these elite positions is extensive. It requires profound, hands-on expertise in software development, system design, and distributed architectures, often with deep specialization in areas like cloud-native development, scalability patterns, or specific technology stacks. Strong proficiency in modern programming languages, databases, and DevOps practices is a given. However, the differentiating factors are strategic thinking, exceptional communication, and leadership. They must articulate complex technical concepts to diverse audiences, advocate for technical investment, and navigate organizational dynamics to drive consensus. A proven track record of leading large-scale, multi-team projects from conception to delivery is essential, alongside a mindset of innovation and a relentless focus on quality and long-term maintainability.

For organizations, hiring for Sr. Principal Engineer jobs is an investment in technical excellence and future-proofing their core technology. For professionals, it is a career stage defined by unparalleled impact, where their technical depth directly shapes the company's trajectory and defines industry standards.