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Senior Technical Program Manager Jobs

94 Job Offers

Senior Technical Program Manager, Productivity Engineering (Data Platform · AI Transformation)
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Senior Technical Program Manager sought to lead AI and Data Platform programs at 10x Genomics in Pleasanton, CA. You will own the roadmap, build processes from scratch, and drive complex data infrastructure and AI transformation initiatives. Ideal for experienced TPMs from mid-stage startups with...
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164100.00 - 222100.00 USD / Year
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10x Genomics
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Senior Technical Program Manager
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114400.00 - 203900.00 CAD / Year
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Microsoft Corporation
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Senior Technical Program Manager - W+D Financial Operations AI and Tooling
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Senior Technical Program Manager needed to own and evolve the RIM platform for Windows + Devices in Redmond, WA. Drive a data-warehouse re-architecting landscape analysis and roadmap to enable AI workflows, Copilot, and Fabric integration. Requires 4+ years in technical program management, cross-...
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119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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Senior Technical Program Manager, AI Execution Architecture
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Senior Technical Program Manager, AI Execution Architecture – Redmond, WA. Drive end-to-end delivery of cross-functional AI programs at Microsoft, partnering with engineering and product teams. Leverage 4+ years of technical program management experience to manage dependencies, mitigate risks, an...
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Microsoft Corporation
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Senior Technical Program Manager
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Senior Technical Program Manager sought by Formlabs to lead complex hardware products from concept to production in Somerville, MA. This in-person role requires 3+ years of program management experience, technical product lifecycle expertise, and cross-functional leadership. You will own program ...
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120000.00 - 180000.00 USD / Year
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Formlabs GmbH
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Senior Technical Program Manager
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Senior Technical Program Manager sought by Microsoft Research in Cambridge, UK, to drive next-gen AI infrastructure. You will translate early-stage research into shippable cloud AI capabilities, managing cross-functional programs spanning optics, photonics, and system design. Requires a Master’s/...
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73800.00 - 121300.00 GBP / Year
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Microsoft Corporation
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Senior & Principal Technical Program Manager
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Microsoft seeks Senior & Principal Technical Program Managers to lead cybersecurity initiatives within its Cloud & AI organization. Based in multiple U.S. locations, this role requires a Bachelor's degree and 4+ years in engineering or program management, plus cross-functional project experience....
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United States, Multiple Locations
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119800.00 USD / Year
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Microsoft Corporation
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Senior Technical Program Manager
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Senior Technical Program Manager needed to drive high-stakes Microsoft 365 tenant onboarding within Microsoft’s internal IT. You will bring clarity to ambiguous problems, managing cross-functional engineering teams and stakeholders across security, finance, and product groups. This role demands 4...
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119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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Senior Technical Program Manager
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Senior Technical Program Manager sought to drive cross-team, high-impact technical programs in Madrid. This individual-contributor leadership role partners with Staff Engineers to execute platform modernization, CI/CD improvements, and system migrations. Requires 5+ years in technical program man...
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Fever
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Senior Manager, Technical Program Management, GenAI
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Lead a high-impact GenAI team at Uber AI Solutions in Hyderabad. As Senior Manager, Technical Program Management, you will scale TPMs delivering complex AI training and evaluation for frontier labs. Requires 15+ years in technical program management, deep GenAI/LLM fluency, and 5+ years managing ...
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Uber
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Senior Technical Program Manager
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Join Microsoft’s ISE team as a Senior Technical Program Manager to design cloud-based solutions with top engineers. You’ll lead cross-functional projects, define success criteria, and drive data-driven recommendations across multiple feature areas. Requires 4+ years in engineering or program mana...
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United States, Multiple Locations
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119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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Senior Technical Program Manager - Insider Risk Investigator
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Microsoft seeks a Senior Technical Program Manager & Insider Risk Investigator to lead operational excellence in insider risk investigations. This role requires a Top Secret/SCI clearance, 6+ years in technical program management, and cross-functional project leadership. You will drive end-to-end...
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United States, Multiple Locations
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142800.00 - 274800.00 USD / Year
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Microsoft Corporation
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Senior Technical Program Manager, Tech and Insights
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Senior Technical Program Manager needed to scale operating frameworks for software planning, testing, and production support within the Technology & Insights team. You will drive cross-functional programs across engineering, product, and analytics, leveraging 8+ years of experience in technical p...
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United States, Minneapolis, MN, Washington D.C., Atlanta, GA, Nashville, TN
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156400.00 - 230000.00 USD / Year
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DoorDash
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Senior Technical Program Manager
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Microsoft seeks a Senior Technical Program Manager in Redmond, WA to lead platform-level programs driving AI transformation and core platform modernization. You will partner with engineering and product leaders to shape the roadmap, ensuring reliability, scalability, and security. Ideal candidate...
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119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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About the Senior Technical Program Manager role

Explore Senior Technical Program Manager Jobs and discover a pivotal leadership role at the intersection of technology, business, and execution. A Senior Technical Program Manager (TPM) is a strategic leader responsible for driving the end-to-end delivery of complex, high-impact technical initiatives. This profession serves as the critical linchpin between engineering teams, product management, and executive stakeholders, ensuring that ambitious technical visions are translated into realistic plans and successfully shipped. Unlike pure project management, this role demands deep technical acumen to understand system architectures, dependencies, and risks, coupled with exceptional organizational and communication skills to align cross-functional teams toward a common goal.

Professionals in these jobs typically own the entire program lifecycle, from initial strategy and roadmap definition through to execution and delivery. Common responsibilities include developing comprehensive program plans, defining milestones, managing resources, and mitigating risks. They are accountable for breaking down large, ambiguous problems into manageable workstreams, often orchestrating the efforts of multiple engineering scrum or product teams. A key aspect of the role is fostering operational excellence, ensuring processes are efficient, and maintaining a balance between feature delivery and managing technical debt. Senior TPMs are also expected to communicate clearly and frequently, providing transparency on progress, challenges, and trade-offs to both technical teams and business leadership.

The typical skill set for Senior Technical Program Manager jobs is a powerful blend of the technical and the interpersonal. A strong background in software engineering, data platforms, or cloud technologies is often essential, allowing these managers to engage meaningfully on solution design and effort estimation. They are proficient in agile and lean methodologies and tools like Jira. Beyond technical knowledge, the role requires stellar leadership: the ability to influence without authority, build consensus among diverse partners, motivate teams, and navigate ambiguous environments. Strategic thinking, analytical problem-solving, and superb verbal and written communication are fundamental. Candidates usually possess a bachelor’s degree in a technical field and many years of combined experience in hands-on technical roles and program/project management, preparing them to lead transformative programs that shape the future of technology-driven organizations.