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Senior Systems Engineer Jobs

368 Job Offers

Senior Systems Engineer
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Lead system-level development and integration for medical devices as a Senior Systems Engineer in San Diego. Apply your 5+ years of experience in requirements management, risk assessment, and DFSS within a cross-functional team. Drive technical leadership and continuous improvement throughout the...
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United States , San Diego
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MillenniumSoft Inc
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Senior Systems Support Engineer
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Seeking a Senior Systems Support Engineer in São Paulo to ensure operational efficiency of complex applications. Utilize your expertise in C#, cloud platforms (AWS/Azure/GCP), and DevOps tools like Docker and CI/CD pipelines. You will debug critical issues, mentor peers, and apply innovative solu...
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Brazil , São Paulo
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Thoughtworks
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Senior Distributed Systems & Detection Engineer
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Join a leading financial crime operations company in Reykjavík as a Senior Distributed Systems & Detection Engineer. Based in Lisboa, you will design deterministic, high-performance data pipelines on an Azure-native platform. Leverage your expertise in Spark, Iceberg, and Trino to enhance AML ope...
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Portugal , Lisboa
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Precise
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Senior Optical Systems Engineer
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Join ICEYE, a global SAR satellite leader, as a Senior Optical Systems Engineer in Warsaw. You will design, simulate, and build high-resolution spaceborne optical payloads from concept through to flight. This role requires deep expertise in imaging optics, Zemax, and hands-on lab testing. We offe...
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Poland , Warsaw
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ICEYE
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Senior Distributed Systems Engineer - Ad Display Platform Engineering
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Join RTB House as a Senior Distributed Systems Engineer in Poland. Build and optimize the high-performance, global Ad Display Platform using Java/Python. Leverage your 7+ years of experience in distributed systems and internet protocols to ensure extreme scalability and reliability. Enjoy flexibl...
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Poland
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RTB House
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Senior Distributed Systems Engineer - Platform Engineering
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Lead the development of complex distributed systems as a Senior Engineer in our Platform Engineering team. You will design scalable solutions for deployment, monitoring, and databases while coordinating a project team. Enjoy flexible work conditions in Poland and apply your expertise in a large-s...
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Poland
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RTB House
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Senior Model-Based Systems Engineer
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Join Banner Defense as a Senior Model-Based Systems Engineer in Colorado Springs. Provide senior technical advisory support, lead MBSE activities for complex DoD systems, and drive digital engineering transformation. Requires a Master's in STEM, 12+ years' experience, active Secret clearance, and...
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United States , Colorado Springs
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115000.00 - 128000.00 USD / Year
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Banner Defense
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Senior Applications Engineer: Thermal Fluid Systems
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Join our Pune team as a Senior Applications Engineer specializing in Thermal Fluid Systems. Utilize your expertise in thermodynamics and 1D system simulation with GT-SUITE to provide top-tier customer support and shape software development. This role offers a dynamic environment, competitive sala...
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India , Pune
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Gamma Technologies
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Senior Network Systems Software Engineer
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Join Aruba, an HPE company, in Bangalore as a Senior Network Systems Software Engineer. Design and develop high-performance, low-latency networking infrastructure in C for routing, switching, and VPN protocols. Leverage 4-10 years of experience in data structures, algorithms, and system-level pro...
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India , Bangalore
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Hewlett Packard Enterprise
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Senior Thermal Protection Systems (TPS) Engineer
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Seeking a part-time Senior TPS Engineer in Houston to provide technical leadership for NASA spacecraft programs. This role requires 15+ years of expertise in thermal protection system design, analysis, and flight certification. You will lead advanced materials development, oversee testing, and gu...
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United States , Houston
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Amentum
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Senior Manufacturing Systems Engineer
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Join Amgen's state-of-the-art FleX Batch manufacturing facility in Holly Springs. Lead automation engineering for GMP drug substance production, utilizing Siemens Desigo CC and PLC systems. This role requires a relevant engineering degree and extensive experience in BAS design and biopharmaceutic...
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United States , Holly Springs
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147421.00 - 177467.00 USD / Year
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Amgen
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Senior Quality Systems Engineer
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Join Cleveland-Cliffs in Windsor as a Senior Quality Systems Engineer. Drive continuous improvement and manage audits (IATF/VDA) in a fast-paced automotive stamping environment. Requires ISO/TS 16949 certification and AIAG Core Tools expertise. We offer excellent compensation, benefits, and caree...
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Canada , Windsor
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75000.00 - 100000.00 USD / Year
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Cleveland-Cliffs
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Senior Systems Engineer - Safety Focus
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Join Boston Dynamics as a Senior Systems Engineer focused on Safety in Waltham, USA. You will lead safety design and compliance for autonomous mobile robots, applying expertise in functional safety standards like ISO 13849. This role requires 5+ years in complex mechatronic systems and offers med...
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United States , Waltham
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154310.00 - 212176.00 USD / Year
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Boston Dynamics
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Senior Systems Engineer
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Join WiseTech Global, a leader in logistics software, as a Senior Systems Engineer in Chicago. You will manage our global Windows & Linux infrastructure, ensuring optimal performance of servers, storage, and networks. This senior role requires deep expertise in virtualization, routing protocols, ...
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United States , Chicago
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Blume Global
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Senior Systems Engineer
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Join BCLP as a Senior Systems Engineer to design and manage complex global enterprise software systems. You will act as a technical SME, leading projects to implement new technology and solve advanced problems. Expertise in Intapp, Boomi, SQL, and cloud migrations is key for this role, which driv...
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Bryan Cave Leighton Paisner LLP
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Senior Enterprise Systems Integration and Support Engineer
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Join mobile.de's IT Enterprise Team in Berlin as a Senior Integration & Support Engineer. You will lead the optimization of key collaboration platforms like Slack and Google Workspace, and manage IAM solutions such as Okta. Leverage your expertise in automation, security frameworks, and cloud env...
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Germany , Berlin
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Adevinta
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Senior Machine Learning Systems Engineer
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Join Abridge in San Francisco as a Senior Machine Learning Systems Engineer. You will build and optimize core ML infrastructure, focusing on scalable Kubernetes clusters and high-performance model serving. Expertise in production ML, distributed systems, and container orchestration is key. Enjoy ...
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United States , San Francisco
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221000.00 - 260000.00 USD / Year
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Abridge
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Senior Systems Engineer I
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Join ICON's Titan Team in Austin as a Senior Systems Engineer I. You will lead hands-on development and technical design for advanced industrial print systems, moving prototypes to production. This role requires 8+ years of systems engineering experience with industrial robotics and automation. A...
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United States , Austin
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ICON
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Senior Staff Systems Engineer, GTM
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Lead the technical strategy for Salesforce CPQ as a Senior Staff Systems Engineer. Architect scalable solutions, integrate key systems, and mentor a team in this high-impact role. Enjoy top benefits like 100% paid medical, RSUs, and a flexible PTO policy in Denver or Oakland.
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United States , Denver; Oakland
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177192.00 - 221490.00 USD / Year
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Fivetran
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Senior Staff Systems Engineer, GTM
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Lead the technical strategy for Salesforce CPQ as a Senior Staff Systems Engineer. This Oakland/Denver-based role requires 10+ years of Salesforce expertise, deep CPQ specialization, and strong architecture skills. You'll drive scalable integrations, mentor engineers, and enjoy top benefits like ...
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United States , Oakland; Denver
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196880.34 - 246100.42 USD / Year
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Fivetran
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About the Senior Systems Engineer role

Explore Senior Systems Engineer Jobs and discover a pivotal career at the intersection of deep technical expertise and strategic project leadership. Senior Systems Engineers are the architectural backbone of complex technological initiatives, responsible for designing, integrating, and maintaining sophisticated systems that form the core infrastructure of modern organizations. This role transcends singular disciplines, requiring a holistic approach to ensure that all system components—whether hardware, software, or network—work seamlessly together to meet business and performance objectives.

Professionals in these senior roles typically bear the responsibility for the entire systems lifecycle. They analyze requirements, architect robust solutions, and oversee implementation and deployment. A core duty involves troubleshooting high-level issues, performing root cause analysis, and ensuring system reliability, security, and scalability. They act as critical liaisons, translating business needs into technical specifications and guiding cross-functional teams of developers, network administrators, and other engineers. Furthermore, Senior Systems Engineers are often tasked with establishing best practices, creating documentation, mentoring junior staff, and driving continuous improvement through automation and process refinement.

The skill set for these jobs is both broad and deep. A strong foundation in systems theory is essential, coupled with expertise in specific domains such as cloud platforms (AWS, Azure, GCP), virtualization, scripting and automation (Python, Bash, PowerShell), and infrastructure as code (Terraform, Ansible). Proficiency in monitoring and observability tools is crucial for maintaining system health. Beyond technical prowess, successful candidates demonstrate exceptional problem-solving abilities, project management skills, and clear communication to interact effectively with both technical teams and stakeholders. Typically, employers seek candidates with a bachelor’s degree in computer science, engineering, or a related field, supplemented by several years of hands-on systems engineering experience, with a proven track record in designing and managing complex, scalable environments.

Senior Systems Engineer jobs represent a career path for seasoned technical professionals ready to take on architectural ownership and strategic influence. These positions are found across every industry, from finance and healthcare to technology and manufacturing, offering the opportunity to build and sustain the critical systems that power innovation and operational excellence. If you are a systems thinker with a passion for integration, optimization, and leadership, exploring Senior Systems Engineer roles could be your next career milestone.