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Senior Systems Engineer United States Jobs

225 Job Offers

Senior Presales Systems Engineer - HPE Networking
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Senior Presales Systems Engineer sought for enterprise and federal customer engagements in San Diego. Leverage 15+ years of expertise in networking, security, and cloud architecture to design Zero Trust and SDN solutions. Drive technical sales, lead workshops, and develop automation with Python a...
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United States of America , San Diego
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Salary
166000.00 - 343000.00 USD / Year
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Hewlett Packard Enterprise
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Senior Legacy Systems Engineer
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Senior Legacy Systems Engineer needed to support USAF logistics and maintenance systems at Maxwell AFB. Requires 10+ years of legacy application support, COBOL, mainframe integration, and active Secret clearance. Lead modernization, refactoring, and coexistence of mission-critical IMDS/IMDS-MSM c...
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United States , Montgomery
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Not provided
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BlueWater Federal Solutions
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Senior Software Engineer, Knowledge Graph/Entity Systems - Microsoft AI Search
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Senior Software Engineer, Knowledge Graph/Entity Systems – Microsoft AI Search in Mountain View, CA. Design and develop AI-powered systems for entity extraction, enrichment, and understanding using machine learning and LLMs. Solve complex challenges in entity resolution and knowledge acquisition ...
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United States , Mountain View
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119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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Senior Manufacturing Engineer – Virtual Engineering, Propulsion Systems
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Senior Manufacturing Engineer – Virtual Engineering, Propulsion Systems at General Motors in Warren, US. Lead digital transformation with Siemens NX, Tecnomatix Process Simulate, and PLM tools. Drive virtual simulation, digital twins, and model-based manufacturing for engines, transmissions, and ...
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United States , Warren
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Not provided
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General Motors
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Senior Hardware Systems Engineer
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Senior Hardware Systems Engineer sought by Crusoe, a vertically integrated AI infrastructure company. Drive the full hardware lifecycle for high-performance compute platforms, leveraging 8+ years of experience in PCIe, InfiniBand, and NVMe debugging. Based in San Francisco, this role offers compe...
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United States , San Francisco
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172000.00 - 209000.00 USD / Year
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Crusoe
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Senior Lead Software Engineer, Distributed Systems (Golang + Python on Kubernetes)
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Senior Lead Software Engineer sought by Capital One to drive AI/ML transformation in San Francisco. You will lead a team building distributed systems using Golang, Python, and Kubernetes on AWS. Requires 6+ years in software engineering and cloud expertise. Join a collaborative team pioneering Ge...
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United States , San Francisco, California
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229900.00 - 286200.00 USD / Year
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Capital One
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Senior Systems Engineer
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Senior Systems Engineer needed in Washington, DC to design and secure enterprise identity infrastructure. This role demands deep expertise in Active Directory, DNS, certificate management, and authentication platforms like ADFS and Okta. You will automate operations with PowerShell, enforce NIST/...
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United States , Washington, DC
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Not provided
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Robert Half
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Senior ML Systems Engineer
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Senior AI/ML Engineer – Shape the future of autonomous driving at GM. Design and build hybrid human/machine labeling tools and pipelines for self-driving vehicles. Leverage Python, TypeScript, Go, and React in a modern full-stack architecture. Enjoy remote/hybrid work near Sunnyvale, CA, plus com...
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United States , Sunnyvale
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170600.00 - 261300.00 USD / Year
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General Motors
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Senior Systems Engineer
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Senior Systems Engineer needed in Annapolis Junction to lead technical integrity across the full systems life cycle. You will apply systems engineering principles to 25 process areas, including requirements analysis, architectural design, and integration. Requires a Bachelor’s degree with 10 year...
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United States , Annapolis Junction
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2HB
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Senior Manufacturing Systems Engineer: Automation
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Join Amgen as a Senior Manufacturing Systems Engineer: Automation in Holly Springs, NC. You will develop and maintain Emerson DeltaV DCS for our advanced FleXbatch facility. Ideal candidates have a degree in Engineering and GMP biopharmaceutical automation experience. Enjoy a comprehensive benefi...
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United States , Holly Springs
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Not provided
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Amgen
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Senior Manufacturing Systems Engineer: Automation (Wednesday - Saturday Shift)
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Join Amgen’s cutting-edge Holly Springs facility as a Senior Manufacturing Systems Engineer (Automation) on a Wednesday-Saturday shift. You’ll develop and maintain Emerson DeltaV DCS systems, transforming process requirements into digital solutions in a GxP environment. Ideal candidates bring 4+ ...
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United States , Holly Springs
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Salary
136906.95 - 185227.05 USD / Year
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Amgen
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Senior Lead Software Engineer, Distributed Systems (Golang + Python on Kubernetes)
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Senior Lead Software Engineer, Distributed Systems (Golang + Python on Kubernetes) sought by Capital One to drive AI/ML transformation. Lead a team building robust cloud-based solutions on AWS, Azure, or GCP. Requires 6+ years in software engineering with expertise in Golang, Python, and Kubernet...
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United States , San Francisco; McLean; New York; San Jose; Cambridge
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Salary
229900.00 - 286200.00 USD / Year
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Capital One
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Senior Radar Systems Engineer
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Senior Radar Systems Engineer needed in Dahlgren, VA to support the AN/SPY-6 radar program. Requires a Bachelor’s in Engineering, Math, or Physics with 10+ years of Surface Navy Radar and Combat Systems experience. Key duties include System Engineering Technical Reviews, Aegis/SSDS integration, a...
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United States , Dahlgren
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100.00 - 110.00 USD / Hour
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Astrion
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Senior Ai Engineer Agentic Systems
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Senior AI Engineer (Agentic Systems) – California. Build autonomous agents that reason over enterprise data and execute multi-step analytics on Teradata Vantage. Requires 3–6 years of software engineering with 2+ years in production agentic AI, Python, and tool-calling protocols. Design agent ski...
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United States , California
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143500.00 - 215200.00 USD / Year
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Teradata
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Senior Robotic Systems Integration Engineer (SLA & SLS)
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Senior Robotic Systems Integration Engineer (SLA & SLS) sought in Somerville, MA. You will lead the integration of firmware and hardware, guiding prototypes through development to optimize complex electro-mechanical systems. Requires 3+ years designing such systems, expertise in motion control, s...
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United States , Somerville
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130000.00 - 163000.00 USD / Year
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Formlabs GmbH
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Senior Robotic Systems Integration Engineer (SLA & SLS)
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Senior Robotic Systems Integration Engineer (SLA & SLS) sought by Formlabs in Boston to lead electro-mechanical system design and integration for groundbreaking 3D printers. You will manage subsystem requirements, define control algorithms, and resolve cross-disciplinary issues using Python or La...
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United States , Boston
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130000.00 - 163000.00 USD / Year
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Formlabs GmbH
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Systems Engineer Senior Level
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Senior-Level Systems Engineer needed for a Woman-Owned Small Business supporting the U.S. Government at Fort Meade. Requires TS/SCI with Full Scope Polygraph, 15+ years of systems engineering experience, and AI/ML expertise with LLM-based systems. Key duties include AI/ML architecture analysis, a...
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United States , Fort Meade
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160000.00 - 225000.00 USD / Year
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Integrity Technology Consultants
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Systems Engineer Senior Level
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Senior-Level Systems Engineer needed in Chantilly, VA to guide multi-discipline engineering for the NSG, ASG, and Federal Agencies. Requires TS/SCI with CI Polygraph, a STEM Bachelor’s degree, and 12+ years in DoD/IC acquisition or systems engineering. Lead requirements, integration, and test for...
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United States , Chantilly
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Not provided
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Integrity Technology Consultants
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Senior Systems Engineer - SME
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Senior Systems Engineer (SME) sought to advise SPD and Chief Engineer on Space Systems Command programs at LA AFB, CA. Leverage 15+ years of systems engineering and acquisition expertise to drive strategic alignment for Resilient MW/MT architecture. Requires active TS/SCI, strong analytical skill...
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United States , El Segundo
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125000.00 - 140000.00 USD / Year
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Tecolote Research
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Systems Engineer Senior Level
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Senior-Level Systems Engineer needed in Fort Meade to support U.S. Government missions. Requires TS/SCI with full-scope Polygraph, 15+ years of systems engineering experience, and knowledge of TradecraftSuite (GAMBIT, HUB). You will drive data-driven analytics, create technical artifacts, and men...
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United States , Fort Meade
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Salary
160000.00 - 225000.00 USD / Year
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Integrity Technology Consultants
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About the Senior Systems Engineer role

Explore Senior Systems Engineer Jobs and discover a pivotal career at the intersection of deep technical expertise and strategic project leadership. Senior Systems Engineers are the architectural backbone of complex technological initiatives, responsible for designing, integrating, and maintaining sophisticated systems that form the core infrastructure of modern organizations. This role transcends singular disciplines, requiring a holistic approach to ensure that all system components—whether hardware, software, or network—work seamlessly together to meet business and performance objectives.

Professionals in these senior roles typically bear the responsibility for the entire systems lifecycle. They analyze requirements, architect robust solutions, and oversee implementation and deployment. A core duty involves troubleshooting high-level issues, performing root cause analysis, and ensuring system reliability, security, and scalability. They act as critical liaisons, translating business needs into technical specifications and guiding cross-functional teams of developers, network administrators, and other engineers. Furthermore, Senior Systems Engineers are often tasked with establishing best practices, creating documentation, mentoring junior staff, and driving continuous improvement through automation and process refinement.

The skill set for these jobs is both broad and deep. A strong foundation in systems theory is essential, coupled with expertise in specific domains such as cloud platforms (AWS, Azure, GCP), virtualization, scripting and automation (Python, Bash, PowerShell), and infrastructure as code (Terraform, Ansible). Proficiency in monitoring and observability tools is crucial for maintaining system health. Beyond technical prowess, successful candidates demonstrate exceptional problem-solving abilities, project management skills, and clear communication to interact effectively with both technical teams and stakeholders. Typically, employers seek candidates with a bachelor’s degree in computer science, engineering, or a related field, supplemented by several years of hands-on systems engineering experience, with a proven track record in designing and managing complex, scalable environments.

Senior Systems Engineer jobs represent a career path for seasoned technical professionals ready to take on architectural ownership and strategic influence. These positions are found across every industry, from finance and healthcare to technology and manufacturing, offering the opportunity to build and sustain the critical systems that power innovation and operational excellence. If you are a systems thinker with a passion for integration, optimization, and leadership, exploring Senior Systems Engineer roles could be your next career milestone.