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Senior System Engineer United States Jobs

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Senior Systems Engineer
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Seeking a Senior Systems Engineer in Jacksonville to manage enterprise servers, cloud platforms (Azure/AWS), and virtualization. You'll deploy, secure, and optimize Windows/Linux environments using scripting and automation. Requires 5+ years' experience with AD, VMware, and compliance. Full benef...
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United States , Jacksonville
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Not provided
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Robert Half
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Systems Engineer Senior Level
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Seeking a TS/SCI with Poly-cleared Senior Systems Engineer in Linthicum. This role requires 20 years' experience leading complex systems engineering, with expertise in data science, NLP, ML, and Python. Enjoy top-tier benefits including a 401K with company contributions, generous PTO, and compreh...
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United States , Linthicum
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100000.00 - 190000.00 USD / Year
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Integrity Technology Consultants
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Systems Engineer Senior Level
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Lead complex systems engineering for critical NSG/ASG geospatial-intelligence programs. This senior role in Chantilly requires TS/SCI with CI Polygraph clearance and 12-18 years' experience in large-scale SoS/SOA. You will guide teams through the full engineering lifecycle, from requirements to i...
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United States , Chantilly
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Integrity Technology Consultants
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Senior Systems Engineer
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Join Ruckus Networks as a Senior Systems Engineer in a virtual US role. You will provide pre-sales engineering and technical enablement to channel partners across several southeastern states. This position requires 5+ years of experience with routers, switches, and Wi-Fi, plus strong presentation...
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United States , Virtual
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Not provided
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CommScope
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Senior Systems Engineer
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Lead system-level development and integration for medical devices as a Senior Systems Engineer in San Diego. Apply your 5+ years of experience in requirements management, risk assessment, and DFSS within a cross-functional team. Drive technical leadership and continuous improvement throughout the...
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United States , San Diego
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MillenniumSoft Inc
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Senior Model-Based Systems Engineer
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Join Banner Defense as a Senior Model-Based Systems Engineer in Colorado Springs. Provide senior technical advisory support, lead MBSE activities for complex DoD systems, and drive digital engineering transformation. Requires a Master's in STEM, 12+ years' experience, active Secret clearance, and...
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United States , Colorado Springs
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115000.00 - 128000.00 USD / Year
Banner Defense
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Senior Level Systems Engineer
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Seeking a TS/SCI with Poly-cleared Senior Systems Engineer in Linthicum. This role requires 20 years' experience leading complex SE efforts, developing system architectures, and providing technical leadership. We offer a robust benefits package including 401K, substantial PTO, and tuition assista...
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United States , Linthicum
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150000.00 - 190000.00 USD / Year
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Integrity Technology Consultants
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Senior Thermal Protection Systems (TPS) Engineer
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Seeking a part-time Senior TPS Engineer in Houston to provide technical leadership for NASA spacecraft programs. This role requires 15+ years of expertise in thermal protection system design, analysis, and flight certification. You will lead advanced materials development, oversee testing, and gu...
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United States , Houston
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Amentum
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Senior Distributed Storage System Engineer
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Join HP as a Senior Distributed Storage System Engineer in San Jose. Design and develop complex software systems and new products, leading project teams and partners. We seek an expert with 6-10 years' experience in software architecture, distributed computing, and cross-platform integration. Enj...
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United States , San Jose
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136500.00 - 276500.00 USD / Year
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Hewlett Packard Enterprise
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Senior Manufacturing Systems Engineer
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Join Amgen's state-of-the-art FleX Batch manufacturing facility in Holly Springs. Lead automation engineering for GMP drug substance production, utilizing Siemens Desigo CC and PLC systems. This role requires a relevant engineering degree and extensive experience in BAS design and biopharmaceutic...
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United States , Holly Springs
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147421.00 - 177467.00 USD / Year
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Amgen
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Senior-Staff Software Engineer, Business Systems
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Seeking a Senior-Staff Software Engineer for Business Systems in San Mateo. Design and implement scalable solutions across AWS, Salesforce, and NetSuite, focusing on data reliability and process automation. Requires 8+ years of distributed systems expertise and AWS cloud services. Enjoy comprehen...
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United States , San Mateo
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180000.00 - 280000.00 USD / Year
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Verkada
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Senior Systems Engineer - Safety Focus
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Join Boston Dynamics as a Senior Systems Engineer focused on Safety in Waltham, USA. You will lead safety design and compliance for autonomous mobile robots, applying expertise in functional safety standards like ISO 13849. This role requires 5+ years in complex mechatronic systems and offers med...
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United States , Waltham
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154310.00 - 212176.00 USD / Year
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Boston Dynamics
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Senior Systems Engineer
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Join WiseTech Global, a leader in logistics software, as a Senior Systems Engineer in Chicago. You will manage our global Windows & Linux infrastructure, ensuring optimal performance of servers, storage, and networks. This senior role requires deep expertise in virtualization, routing protocols, ...
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United States , Chicago
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Blume Global
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Senior Systems Engineering Manager
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Lead mechanical and electrical equipment specification for cutting-edge data center projects in San Francisco. This senior management role requires deep MEP expertise, vendor bid leveling, and multi-project oversight. Enjoy top benefits like stock units, comprehensive health plans, and a strong 4...
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United States , San Francisco
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190000.00 - 220000.00 USD / Year
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Crusoe
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Senior Robotic Systems Integration Engineer
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Join Formlabs as a Senior Robotic Systems Integration Engineer in Somerville. Integrate firmware and hardware for advanced 3D printers, defining control algorithms and managing system requirements. Utilize your 5+ years in robotic systems, motion control, and Python scripting within a collaborati...
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United States , Somerville
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125000.00 - 180000.00 USD / Year
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Formlabs GmbH
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Senior Robotic Systems Integration Engineer
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Join Formlabs in Boston to shape the future of fabrication as a Senior Robotic Systems Integration Engineer. You will integrate firmware and hardware, define control algorithms, and debug complex electro-mechanical systems for advanced 3D printers. This role requires 5+ years of experience in rob...
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United States , Boston
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125000.00 - 180000.00 USD / Year
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Formlabs GmbH
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Senior Machine Learning Systems Engineer
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Join Abridge in San Francisco as a Senior Machine Learning Systems Engineer. You will build and optimize core ML infrastructure, focusing on scalable Kubernetes clusters and high-performance model serving. Expertise in production ML, distributed systems, and container orchestration is key. Enjoy ...
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United States , San Francisco
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221000.00 - 260000.00 USD / Year
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Abridge
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Senior Mechanical Engineer I, Off-Planet Systems
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Join ICON's Strategic R&D team as a Senior Mechanical Engineer for Off-Planet Systems. You will design electro-mechanical robotics and hardware for lunar construction in Austin, TX. This role requires 8+ years of mechanical design experience, proficiency in SolidWorks, and a strong R&D background...
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United States , Austin
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Not provided
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ICON
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Senior Systems Engineer I
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Join ICON's Titan Team in Austin as a Senior Systems Engineer I. You will lead hands-on development and technical design for advanced industrial print systems, moving prototypes to production. This role requires 8+ years of systems engineering experience with industrial robotics and automation. A...
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United States , Austin
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ICON
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Senior Staff Systems Engineer, GTM
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Lead the technical strategy for Salesforce CPQ as a Senior Staff Systems Engineer. Architect scalable solutions, integrate key systems, and mentor a team in this high-impact role. Enjoy top benefits like 100% paid medical, RSUs, and a flexible PTO policy in Denver or Oakland.
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United States , Denver; Oakland
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177192.00 - 221490.00 USD / Year
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Fivetran
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Discover and apply for Senior System Engineer jobs, a critical and high-impact career path at the intersection of technology, strategy, and complex problem-solving. Senior System Engineers are the master architects and technical leaders responsible for designing, integrating, and maintaining the sophisticated systems that power modern enterprises and critical infrastructure. This role transcends basic IT support, focusing on the holistic lifecycle of large-scale systems, from initial concept and requirements analysis through to deployment, integration, and ongoing optimization. Professionals in these senior-level jobs act as the crucial bridge between business objectives, user needs, and technical execution. A typical day involves analyzing high-level requirements and translating them into detailed system specifications and architectural blueprints. They guide cross-functional engineering teams, ensuring that various components—hardware, software, network, and cloud services—work seamlessly together as a cohesive system. A core responsibility is leading systems integration efforts, developing comprehensive test plans, and managing the technical integrity of major projects. Furthermore, Senior System Engineers are often tasked with evaluating new technologies, conducting feasibility studies and trade-off analyses, and developing strategic roadmaps to evolve system capabilities while ensuring reliability, security, and scalability. The skill set required for Senior System Engineer jobs is both broad and deep. A strong foundation in systems engineering principles and methodologies is paramount. Candidates typically possess extensive experience with the full systems development lifecycle (SDLC) and are proficient in creating essential documentation such as System Engineering Plans (SEP) and architecture diagrams. Technical expertise often includes knowledge of cloud platforms, cybersecurity principles, and scripting or programming languages like Python for automation and tooling. Beyond technical acumen, these roles demand exceptional analytical and problem-solving skills to deconstruct complex challenges. Leadership and communication are equally critical, as Senior System Engineers must mentor junior staff, collaborate with stakeholders across departments, and clearly articulate technical concepts to non-technical executives and government overseers. Typical requirements for these positions include a bachelor’s or master’s degree in systems engineering, computer science, information technology, or a related STEM field. Most roles require a substantial professional background, often 10+ years of progressive experience in systems engineering, with a proven track record of leading projects of significant scope and complexity. While specific security clearances are context-dependent for government roles, a general emphasis on systems that handle sensitive data is common. For those seeking a career where they can shape technological strategy and ensure the robustness of mission-critical operations, exploring Senior System Engineer jobs offers a challenging and rewarding pathway.

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