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Senior Software Systems Engineer Jobs

38 Job Offers

Senior Systems Software Engineer
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Join Exact Sciences in Madison as a Senior Systems Software Engineer. Architect and develop embedded software for robotics and medical instrumentation to scale life-saving cancer tests. This role requires 6+ years' experience, a software engineering degree, and expertise in the full development l...
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United States , Madison
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101000.00 - 172000.00 USD / Year
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Exact Sciences
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Senior Software Engineer - Build Systems
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Join Microsoft as a Senior Software Engineer specializing in Build Systems. Modernize compilers and developer tooling for large-scale, cloud-first applications in Redmond. Leverage AI-powered tools to solve complex engineering challenges and improve developer efficiency. Requires expertise in C/C...
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United States , Redmond
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119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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Senior Systems Software Engineer
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Join our team in Palo Alto as a Senior Systems Software Engineer for Vision. You will design and optimize low-latency, high-throughput vision subsystems for humanoid robots. This role requires deep C++/Linux expertise and experience with real-time systems, hardware accelerators, and performance o...
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United States , Palo Alto
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137861.00 - 240000.00 USD / Year
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1X Technologies
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Senior Software Engineer - ERP Systems
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Lead the internal software stack powering sales, manufacturing, and supply chain. Architect full-stack systems on Odoo/NetSuite with Python, React, and PostgreSQL. Design APIs, integrate with PLM/MES, and own projects from design to deployment. This Palo Alto role offers competitive benefits for ...
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United States , Palo Alto
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150000.00 - 221000.00 USD / Year
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1X Technologies
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Senior Power Systems Software Engineer
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Join a high-level R&D team in Paris as a Senior Power Systems Software Engineer. Design and develop innovative energy sector solutions using Java, Python, and C++. We seek an expert with strong algorithm design skills and knowledge of Kubernetes/DevOps. Enjoy flexible hours and a central office l...
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France , Paris
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Not provided
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Artelys
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Senior Software Engineer - Systems
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Join our Product team in Hobart or Sydney as a Senior Software Engineer - Systems. Develop the core C++ systems powering Procreate Dreams, focusing on animation, audio, and real-time performance. We seek an expert in multi-threaded concurrency, CPU optimization, and library development. Visa supp...
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Australia , Hobart; Sydney
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Not provided
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Procreate
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Senior Software Engineer – GTM Systems
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Join Intercom as a Senior Software Engineer for GTM Systems in Chicago. Design and build scalable internal systems using Python, SQL, and Salesforce. Leverage data tools like Snowflake and DBT, and work on AI-driven tooling. Enjoy competitive compensation, comprehensive benefits, and a collaborat...
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United States , Chicago
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185000.00 - 220000.00 USD / Year
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Intercom
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Systems Software Senior Engineer
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Join our team in Hyderabad as a Senior Endpoint Systems Engineer. Provide technical leadership for endpoint engineering, focusing on MECM, Intune, and cloud DaaS. Enjoy a collaborative culture, career development, and comprehensive benefits in this onsite role.
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India , Hyderabad
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Not provided
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TTEC
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Senior Software Systems Engineer
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Join our R&D team in Raleigh as a Senior Software Systems Engineer. Develop groundbreaking infusion pump platforms and connected digital healthcare applications. Apply your Agile, requirements management, and regulated product expertise in a collaborative environment. We offer comprehensive benef...
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United States , Raleigh
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Salary
96000.00 - 132000.00 USD / Year
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Baxter
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Senior Principal Software Systems Engineer
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Lead groundbreaking healthcare innovation as a Senior Principal Software Systems Engineer in Raleigh. Develop infusion pump platforms and digital apps using Agile methodologies in a regulated medical device environment. This role requires 10+ years of experience and offers a robust benefits packa...
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United States , Raleigh
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128000.00 - 176000.00 USD / Year
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Baxter
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Senior Software Systems Engineer
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Join our R&D team in Raleigh as a Senior Software Systems Engineer. Develop groundbreaking infusion pump platforms and connected digital healthcare applications. We seek expertise in Agile, requirements management, and regulated systems. Enjoy comprehensive benefits, including health coverage fro...
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United States , Raleigh
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Salary
96000.00 - 132000.00 USD / Year
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Baxter
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Senior Principal Software Systems Engineer
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Lead groundbreaking healthcare innovation as a Senior Principal Software Systems Engineer in Raleigh. You will drive new product development for Infusion Pump Platforms using Agile methodologies in a regulated medical device environment. This role requires 10+ years of experience and offers a com...
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United States , Raleigh
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Salary
128000.00 - 176000.00 USD / Year
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Baxter
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Senior Principal Software Systems Engineer
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Lead groundbreaking healthcare innovation as a Senior Principal Software Systems Engineer in Raleigh. Utilize your 10+ years of experience in regulated medical devices to develop infusion pump platforms and digital applications. Drive Agile SDLC, mentor teams, and solve complex challenges in a ro...
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United States , Raleigh
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Salary
128000.00 - 176000.00 USD / Year
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Baxter
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Senior Software Systems Engineer
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Join our R&D team in Raleigh as a Senior Software Systems Engineer. Develop groundbreaking infusion pump platforms and connected digital healthcare applications. We seek an expert in Agile, requirements management, and regulated medical device development. Enjoy comprehensive benefits from day on...
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Location
United States , Raleigh
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Salary
96000.00 - 132000.00 USD / Year
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Baxter
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Senior-Staff Software Engineer, Business Systems
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Join our Business Systems Engineering team as a Senior-Staff Software Engineer in San Mateo. Design and implement scalable solutions across AWS, Salesforce, and NetSuite, focusing on data reliability and process automation. We seek an expert in distributed systems with 8+ years of experience and ...
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United States , San Mateo
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Salary
180000.00 - 300000.00 USD / Year
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Verkada
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Senior Software Engineer, Business Systems
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Join Verkada as a Senior Software Engineer for Business Systems in San Mateo. Design and build scalable distributed systems using AWS, Kubernetes, and DynamoDB. Lead projects end-to-end in a fast-paced environment, with top-tier health benefits fully covered for employees.
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United States , San Mateo
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Salary
180000.00 - 300000.00 USD / Year
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Verkada
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Systems Software Senior Engineer
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Seeking a Senior Endpoint Systems Engineer in Hyderabad to provide technical leadership. You will manage MECM, Intune, and cloud DaaS infrastructure, ensuring security and reliability. This role requires 5+ years of experience, PowerShell skills, and offers strong benefits with career growth.
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India , Hyderabad
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Not provided
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TTEC
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Senior Network Systems Software Engineer
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Join Aruba, an HPE company, in Bangalore as a Senior Network Systems Software Engineer. Design and develop high-performance, low-latency networking infrastructure in C for routing, switching, and VPN protocols. Leverage 4-10 years of experience in data structures, algorithms, and system-level pro...
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India , Bangalore
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Not provided
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Hewlett Packard Enterprise
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About the Senior Software Systems Engineer role

A career in senior software systems engineering represents the apex of technical leadership and architectural design within the software development lifecycle. Professionals in these roles are responsible for designing, integrating, and maintaining the complex systems that underpin modern technology infrastructure. Unlike junior developers who focus on individual features, senior software systems engineers take a holistic view, ensuring that software components interact seamlessly with hardware, operating systems, networks, and other services. This profession is critical for organizations that rely on robust, scalable, and high-performance platforms, from cloud computing and embedded devices to enterprise applications and artificial intelligence systems.

The core responsibilities of a senior software systems engineer typically span the entire system architecture. They are tasked with defining technical strategy, selecting appropriate technologies, and establishing build systems that ensure code is compiled, tested, and deployed efficiently. A significant portion of the role involves optimizing performance—identifying bottlenecks in memory usage, processing speed, or network latency. These engineers often work on the "plumbing" behind the scenes: developing middleware, managing system-level libraries, and creating the foundational layers that application developers build upon. Another common duty is designing and maintaining CI/CD (Continuous Integration/Continuous Deployment) pipelines, which automate testing and release processes. Because these roles sit at the intersection of software and hardware, professionals frequently collaborate with hardware engineers, product managers, and other software teams to align system capabilities with business goals. Mentorship is also a hallmark of seniority; experienced engineers guide junior team members, conduct code reviews, and set coding standards.

To succeed in senior software systems engineering jobs, candidates need a deep, multi-faceted skill set. Proficiency in systems-level programming languages like C, C++, and C# is almost always required, along with experience in scripting languages such as Python for automation and tooling. A strong understanding of operating system concepts (memory management, threading, process scheduling) is essential, as is knowledge of networking protocols and distributed systems principles. Many roles demand familiarity with build tools (CMake, Bazel), version control systems, and containerization technologies (Docker, Kubernetes). For those working with specialized hardware, experience with embedded systems, real-time operating systems, or GPU programming is highly valued. Beyond technical skills, soft skills are paramount: the ability to communicate complex architectural decisions to non-technical stakeholders, lead cross-functional initiatives, and make trade-offs between performance, security, and maintainability.

Typical requirements for these positions include a bachelor’s degree in computer science, software engineering, or a related field, coupled with four to six years of progressive engineering experience. Many employers also require the ability to pass security screenings, especially for roles involving cloud infrastructure or sensitive data. The demand for senior software systems engineers continues to grow as companies build more complex, interconnected products. For professionals who enjoy solving hard problems, designing robust architectures, and seeing their work impact millions of users, these jobs offer a challenging and rewarding career path with significant influence over the technology of tomorrow.