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Senior Python Engineer Jobs (Remote work)

44 Job Offers

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Senior Software Engineer - Conversational AI (Python)
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Join Team Vector as a Senior Software Engineer in Estonia to build agentic voice AI for banking. Requires production AI systems experience, Python skills, and strong architecture judgment.
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Glia
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Senior Python Backend Engineer, Financial Systems
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Senior Python Backend Engineer for financial systems at AI-driven Makers. Fully remote (Argentina/Brazil), long-term contractor. Requires 5+ years Python, Django, SQL, financial APIs, and daily agentic AI coding tools like Claude and Cursor.
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BriteCore
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Senior Python Backend Engineer
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Senior Python Backend Engineer for a fully remote long-term contract (Argentina/Brazil). Requires 5+ years Python, Django, SQL, AWS, Docker and daily hands-on use of agentic AI coding tools like Claude and Cursor.
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BriteCore
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Senior Python Backend Developer / ML Engineer (IR-555)
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Senior Python Backend Developer/ML Engineer needed to build scalable FastAPI systems and production LLM solutions. Requires 7+ years Python, 2+ years ML/LLM experience, RAG architectures, LangChain, and vector databases. Remote-friendly with flexible hours and growth opportunities.
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Intellectsoft
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Senior Backend Python Engineer (Core Gateway)
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Senior Backend Python Engineer needed for Core Gateway team at payabl. Remote from Poland. Requires 5+ years Python (FastAPI, AsyncIO), Perl flexibility, API integrations, Docker, AWS. Annual learning budget and global events.
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payabl
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Senior Open-Source Python Engineer, ML Developer Tools - US Remote
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Hugging Face
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Senior Open-Source Python Engineer, ML Developer Tools - EMEA Remote
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Hugging Face
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Senior Python, Cloud Infrastructure & AI Engineer
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India, India
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Everbridge
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Senior Python Data Engineer (OCR & Document Processing)- remote
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Inetum
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Senior Python Backend Developer / Platform Engineer- remote
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Inetum
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Senior Staff Software Engineer | Security Data Platform | Expert in Python
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Armis
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Senior Python Software Engineer
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Romania, Employees can work remotely
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Accesa
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Senior Python Backend Engineer
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Canada, Canada
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3Pillar Global
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Senior Python Software Engineer / RDM
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https://www.inetum.com Logo
Inetum
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Senior Python Software Engineer
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Romania, Romania
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3pillarglobal.com Logo
3Pillar Global
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Senior Python Software Engineer
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Czech Republic, Czech Republic
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3pillarglobal.com Logo
3Pillar Global
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Senior Python Software Engineer - Data Engineer
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3pillarglobal.com Logo
3Pillar Global
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Senior Python Software Engineer - Data Engineer
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3pillarglobal.com Logo
3Pillar Global
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Senior Full-Stack Software Engineer (Python / React)
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Romania, Romania
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3Pillar Global
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Senior Full-Stack Software Engineer (Python / React)
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Moldova, Moldova
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3pillarglobal.com Logo
3Pillar Global
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About the Senior Python Engineer role

Looking for Senior Python Engineer jobs means seeking a pivotal role at the intersection of deep technical expertise and strategic software development. A Senior Python Engineer is a seasoned professional responsible for designing, building, and maintaining robust, scalable, and efficient software systems using the Python programming language. This role transcends basic coding; it involves architectural decision-making, mentoring, and owning the full software development lifecycle to drive business-critical applications and platforms.

Professionals in these roles typically shoulder a wide array of responsibilities. They architect and implement backend services, RESTful APIs, and data processing pipelines. A core part of the job is writing clean, maintainable, and testable code while advocating for best practices in software engineering. They are expected to lead the technical direction of projects, making key decisions on frameworks, tools, and system design patterns to ensure reliability and scalability. Collaboration is fundamental, as Senior Python Engineers frequently partner with product managers, designers, and other engineering teams to translate complex requirements into technical specifications. They also play a crucial role in operational excellence, which includes monitoring system performance, troubleshooting production issues, and ensuring the security and robustness of applications. Furthermore, they often contribute to DevOps practices, enhancing CI/CD pipelines to streamline deployment and improve development velocity.

The typical skill set for Senior Python Engineer jobs is comprehensive. Mastery of Python and its ecosystem (e.g., frameworks like Django, Flask, or FastAPI) is a given. Strong experience with system design, data structures, algorithms, and software architecture principles is essential. Familiarity with cloud platforms (AWS, GCP, Azure), containerization technologies like Docker and Kubernetes, and infrastructure-as-code is highly common. A deep understanding of databases, both SQL (e.g., PostgreSQL) and NoSQL, is required. Beyond technical prowess, successful candidates demonstrate excellent problem-solving abilities, a product-oriented mindset, and strong communication skills to articulate complex concepts to diverse stakeholders. They exhibit a high degree of ownership, from initial concept through to deployment and maintenance. While requirements vary, most positions seek individuals with 5+ years of relevant experience, a proven track record of delivering complex systems, and a commitment to continuous learning and mentoring junior team members. Exploring Senior Python Engineer jobs opens doors to roles where technical leadership directly impacts product innovation and technological advancement.