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Senior IT Systems Engineer Jobs

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Senior Manufacturing Systems Engineer
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Join Amgen's state-of-the-art FleX Batch manufacturing facility in Holly Springs. Lead automation engineering for GMP drug substance production, utilizing Siemens Desigo CC and PLC systems. This role requires a relevant engineering degree and extensive experience in BAS design and biopharmaceutic...
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United States , Holly Springs
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147421.00 - 177467.00 USD / Year
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Amgen
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Senior-Staff Software Engineer, Business Systems
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Seeking a Senior-Staff Software Engineer for Business Systems in San Mateo. Design and implement scalable solutions across AWS, Salesforce, and NetSuite, focusing on data reliability and process automation. Requires 8+ years of distributed systems expertise and AWS cloud services. Enjoy comprehen...
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United States , San Mateo
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180000.00 - 280000.00 USD / Year
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Verkada
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Senior Quality Systems Engineer
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Join Cleveland-Cliffs in Windsor as a Senior Quality Systems Engineer. Drive continuous improvement and manage audits (IATF/VDA) in a fast-paced automotive stamping environment. Requires ISO/TS 16949 certification and AIAG Core Tools expertise. We offer excellent compensation, benefits, and caree...
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Canada , Windsor
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75000.00 - 100000.00 USD / Year
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Cleveland-Cliffs
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Senior Systems Engineer - Safety Focus
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Join Boston Dynamics as a Senior Systems Engineer focused on Safety in Waltham, USA. You will lead safety design and compliance for autonomous mobile robots, applying expertise in functional safety standards like ISO 13849. This role requires 5+ years in complex mechatronic systems and offers med...
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United States , Waltham
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154310.00 - 212176.00 USD / Year
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Boston Dynamics
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Senior Systems Engineer
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Join WiseTech Global, a leader in logistics software, as a Senior Systems Engineer in Chicago. You will manage our global Windows & Linux infrastructure, ensuring optimal performance of servers, storage, and networks. This senior role requires deep expertise in virtualization, routing protocols, ...
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United States , Chicago
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Not provided
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Blume Global
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Senior Systems Engineer
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Join BCLP as a Senior Systems Engineer to design and manage complex global enterprise software systems. You will act as a technical SME, leading projects to implement new technology and solve advanced problems. Expertise in Intapp, Boomi, SQL, and cloud migrations is key for this role, which driv...
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Bryan Cave Leighton Paisner LLP
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Senior Enterprise Systems Integration and Support Engineer
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Join mobile.de's IT Enterprise Team in Berlin as a Senior Integration & Support Engineer. You will lead the optimization of key collaboration platforms like Slack and Google Workspace, and manage IAM solutions such as Okta. Leverage your expertise in automation, security frameworks, and cloud env...
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Germany , Berlin
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Adevinta
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Senior Systems Engineering Manager
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Lead mechanical and electrical equipment specification for cutting-edge data center projects in San Francisco. This senior management role requires deep MEP expertise, vendor bid leveling, and multi-project oversight. Enjoy top benefits like stock units, comprehensive health plans, and a strong 4...
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United States , San Francisco
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190000.00 - 220000.00 USD / Year
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Crusoe
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Senior Machine Learning Systems Engineer
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Join Abridge in San Francisco as a Senior Machine Learning Systems Engineer. You will build and optimize core ML infrastructure, focusing on scalable Kubernetes clusters and high-performance model serving. Expertise in production ML, distributed systems, and container orchestration is key. Enjoy ...
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United States , San Francisco
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221000.00 - 260000.00 USD / Year
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Abridge
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Senior Systems Engineer I
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Join ICON's Titan Team in Austin as a Senior Systems Engineer I. You will lead hands-on development and technical design for advanced industrial print systems, moving prototypes to production. This role requires 8+ years of systems engineering experience with industrial robotics and automation. A...
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United States , Austin
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ICON
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Senior Staff Systems Engineer, GTM
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Lead the technical strategy for Salesforce CPQ as a Senior Staff Systems Engineer. Architect scalable solutions, integrate key systems, and mentor a team in this high-impact role. Enjoy top benefits like 100% paid medical, RSUs, and a flexible PTO policy in Denver or Oakland.
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United States , Denver; Oakland
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177192.00 - 221490.00 USD / Year
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Fivetran
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Senior Staff Systems Engineer, GTM
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Lead the technical strategy for Salesforce CPQ as a Senior Staff Systems Engineer. This Oakland/Denver-based role requires 10+ years of Salesforce expertise, deep CPQ specialization, and strong architecture skills. You'll drive scalable integrations, mentor engineers, and enjoy top benefits like ...
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United States , Oakland; Denver
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196880.34 - 246100.42 USD / Year
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Fivetran
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Senior RF Systems Engineer
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Join a leading team in Ottawa as a Senior RF Systems Engineer, specializing in advanced satellite communications. You will apply your deep expertise in DVB-S2X/RCS2 standards, ACM, and antenna technologies within a systems engineering framework. This role requires a Master's degree and 10+ years ...
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Canada , Ottawa
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110000.00 - 140000.00 USD / Year
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Myticas Consulting
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Senior IT Systems Engineer
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Seeking a Senior IT Systems Engineer to scale corporate infrastructure with a DevOps mindset. This hands-on role requires expertise in cloud (GCP/AWS/Azure), scripting (Python/PowerShell), and automation (Terraform, Okta). You will build reliable systems, automate IT processes, and enhance the em...
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United States
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185000.00 - 226000.00 USD / Year
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Mixpanel
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Senior Power Systems Engineer
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Join a global leader in renewable energy as a Senior Power Systems Engineer in Bengaluru. Apply your 5-10 years of expertise in grid connection studies and tools like DIgSILENT/PSS/E to solve complex challenges for new projects. Enjoy professional growth, flexible remote work, and a role critical...
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India , Bengaluru
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360 Resourcing Solutions
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Senior Distributed Systems Engineer - Ad Display
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Join RTB House as a Senior Distributed Systems Engineer for Ad Display. Design and implement high-performance, scalable global systems for ad display and tracking using Java/Python. Leverage 8+ years of software engineering experience in a role focusing on extreme performance and high code qualit...
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Poland
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RTB House
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Senior Segment Systems Engineer
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Lead the development of mission-critical satellite ground systems as a Senior Segment Engineer in Berkshire. You will own the full lifecycle, from concept to operations, for Mission Control and Planning systems. This autonomous role requires expertise in SCOS-2000, ground segment architecture, an...
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United Kingdom , Berkshire
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50000.00 - 65000.00 GBP / Year
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BLUESTREAM PEOPLE
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Senior AI Engineer – Agentic Systems
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Join a pioneering team in Dubai as a Senior AI Engineer, building autonomous agentic systems for enterprise workflows. You will design and deploy production-grade AI agents using LLMs, RAG, and orchestration tools like LangGraph. This foundational role offers top-tier compensation, equity, and a ...
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United Arab Emirates , Dubai
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Salt
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Senior Systems Engineer
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Join a pioneering team as a Senior Systems Engineer, shaping the future of revolutionary seaglider vehicles. You will develop certification-focused systems engineering artifacts and drive verification in a safety-critical, regulated environment. This role in North Kingstown offers competitive com...
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United States , North Kingstown
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Not provided
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REGENT Craft
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Senior Engineer, Mechanical Mission Systems
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Seeking a Senior Mechanical Engineer in North Vancouver to lead marine mission systems design. This role requires a P.Eng. with 10+ years in mechanical systems, focusing on launch/recovery, winches, and hydraulics. You will oversee projects from concept to close-out, ensuring compliance with all ...
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Canada , North Vancouver
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119700.00 - 146300.00 CAD / Year
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Washington Corporations
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Are you a seasoned technical expert seeking to architect, build, and maintain the critical infrastructure that powers modern enterprises? Explore senior IT systems engineer jobs, where your deep expertise becomes the backbone of organizational resilience and innovation. This senior-level role is the pinnacle of systems engineering, demanding a strategic mindset, profound technical knowledge, and leadership capabilities to design and oversee complex, integrated systems that meet rigorous business and technical demands. Senior IT Systems Engineers are the master architects and custodians of an organization's core technology environment. They move beyond routine maintenance to engage in high-level design, strategic planning, and solving the most challenging technical problems. A typical day involves designing robust system architectures, automating processes for scale and efficiency, and ensuring the highest levels of security, availability, and performance. They serve as the technical authority, guiding projects from conception through to implementation and commissioning, often acting as the crucial bridge between business objectives and technical execution. Common responsibilities in these senior roles are comprehensive and impactful. Professionals typically lead the design and implementation of critical systems, which can include server infrastructure, cloud platforms, network architectures, or specialized industrial control and automation systems. They develop and enforce standards, create detailed documentation, and establish governance models. A significant part of the role involves mentoring junior engineers, providing technical leadership to cross-functional teams, and collaborating with stakeholders to translate requirements into reliable technical solutions. They are also responsible for capacity planning, disaster recovery strategies, root-cause analysis for major incidents, and driving continuous improvement initiatives to optimize system performance and reduce operational overhead. The skill set required for senior IT systems engineer jobs is both broad and deep. Typically, employers seek candidates with a bachelor's degree in computer science, engineering, or a related field, coupled with 8-15 years of progressive hands-on experience. Expertise in core technologies is a given—this may include advanced proficiency in operating systems (Linux/Windows), virtualization (VMware, Hyper-V), cloud services (AWS, Azure, GCP), networking, scripting and automation (Python, PowerShell, Ansible, Terraform), and often specialized knowledge in areas like PLC/SCADA for industrial roles or specific security frameworks. Beyond technical prowess, exceptional problem-solving, analytical thinking, and communication skills are paramount. Senior engineers must articulate complex concepts to non-technical audiences, manage multiple priorities, lead by influence, and proactively research emerging technologies to guide future strategy. If you are ready to take ownership of enterprise-scale systems and provide the technical vision that drives business success, exploring senior IT systems engineer jobs is your next strategic career move.

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