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Senior AI Engineer United States, SAN FRANCISCO Jobs

30 Job Offers

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Senior ML Engineer, Agentic AI
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Lead Agentic AI innovation at Ellipsis Health in San Francisco. Architect scalable LLM-powered multi-agent systems, guide engineering pods, and translate frontier ML research into production. Requires 5+ years software development and deep Python/ML framework expertise.
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Ellipsis Health
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Senior Computer Vision Engineer, Embodied AI
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Senior Computer Vision Engineer for Embodied AI in San Francisco. Requires 5+ years CV experience, 3D scene understanding, open-vocabulary segmentation and production ML systems. Hybrid role, 3 days in office, with bonus and equity.
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229500.00 - 255000.00 USD / Year
Niantic Spatial
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Senior Staff Applied AI Inference Engineer
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Senior Staff Applied AI Inference Engineer in San Francisco to optimize LLM inference end to end. Requires Python/C++, vLLM or SGLang, GPU profiling, and CUDA kernel-level tuning. Hands-on production role with customer-facing work and strong benefits.
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Crusoe
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Senior Full Stack Engineer - AI Innovation
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Lead AI innovation at Taskrabbit as Senior Full Stack Engineer in San Francisco. Requires 5+ years with Node.js, microservices, Kafka, and SQL. Hybrid role driving technical strategy and mentoring engineers.
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Taskrabbit
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Senior Applied AI Engineer
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Join Abby Care as a Senior Applied AI Engineer in San Francisco. Lead end-to-end AI systems, build reliable agents and copilots, and design rigorous evaluations. Requires 5+ years of software engineering or applied AI experience with production ML systems.
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Abby Care
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Senior / Staff AI Platform Engineer
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Suno seeks a Senior/Staff AI Platform Engineer in San Francisco to build platform APIs, SDKs, and eval infrastructure powering agent features. Requires 4-6 years of backend/platform experience and production LLM systems.
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Suno
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Senior Applied AI Engineer 2
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Senior Applied AI Engineer role at Drata in San Francisco. Requires 6+ years in applied research/ML with NLP and information retrieval expertise, RAG systems, and evaluation methodology. Build agentic AI for compliance automation.
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Drata
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Senior Staff AI-Native Software Engineer – Agentic Systems
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ServiceNow seeks a Senior Staff AI-Native Software Engineer in San Francisco to design and ship production-grade multi-agent systems. Requires 8+ years in software engineering, Python, and hands-on agentic AI experience.
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Armis
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Senior AI Agent Engineer | Moveworks
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Armis
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Senior Staff AI-Native Software Engineer – Agentic Systems
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Armis
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Senior Staff AI Agent Engineer – Moveworks | Customer Deployment
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Armis
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Senior AI Agent Engineer | Moveworks - Federal
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Armis
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Senior Software Engineer - Developer Experience & AI Enablement
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200000.00 - 250000.00 USD / Year
Grow Therapy
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Senior Full-Stack Software Engineer, AI
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United States, San Francisco Bay Area
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Mainstay Labs Inc.
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Senior Frontier Agents Engineer (Applied AI)
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Scale
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Senior AI Automation Engineer
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United States, Boston, Chicago, Los Angeles, New York, San Francisco, Toronto, Vancouver
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110000.00 - 160000.00 CAD / Year
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Later
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Senior Software Engineer, Voice AI
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Nooks
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Senior Forward Deployed Engineer, AI Infrastructure & Deployments
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United States, New York, San Francisco
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191000.00 - 253000.00 USD / Year
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Mavens
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Senior Computer Vision / Applied AI Engineer
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United States, San Francisco Bay Area
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160000.00 - 200000.00 USD / Year
Simbe Robotics
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Senior Software Engineer, AI Product Insights
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Mixpanel
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About the Senior AI Engineer role

Explore the frontier of technology by pursuing Senior AI Engineer jobs, a critical role at the intersection of advanced research and real-world application. Senior AI Engineers are the architects and builders of intelligent systems, responsible for transforming theoretical machine learning models into robust, scalable, and impactful solutions. This senior-level position demands not only deep technical expertise but also strategic vision to guide projects from conception through to deployment and maintenance.

Professionals in this role typically engage in the full lifecycle of AI development. Common responsibilities include designing and implementing sophisticated machine learning and deep learning models, which may involve areas like computer vision, natural language processing (NLP), generative AI, or reinforcement learning. A significant part of the role focuses on MLOps—building and maintaining pipelines for continuous integration and deployment (CI/CD) to ensure models can be reliably trained, versioned, and deployed into production environments. They build high-performance APIs to serve these models and integrate them seamlessly with existing business applications and data systems. Furthermore, Senior AI Engineers are tasked with rigorous model evaluation, performance monitoring, and optimization to ensure solutions remain effective and efficient over time.

Beyond pure model building, these engineers often champion software engineering best practices within data science teams, emphasizing clean code, thorough testing, and comprehensive documentation. They collaborate closely with data engineers, software developers, and business stakeholders to align technical efforts with organizational goals. Leadership is a key component; senior professionals frequently mentor junior team members, make pivotal technology stack decisions, and drive the adoption of new methodologies and tools.

Typical skills and requirements for Senior AI Engineer jobs include an advanced degree (Master's or PhD) in Computer Science, Machine Learning, or a related quantitative field, coupled with 5+ years of hands-on experience. Expert proficiency in Python and its core data science libraries (e.g., Pandas, NumPy, Scikit-learn) is essential, as is deep practical knowledge of frameworks like TensorFlow or PyTorch. Experience with cloud platforms (AWS, Azure, GCP) for scalable computing, containerization tools like Docker, and orchestration systems such as Kubernetes is highly valued. A strong understanding of software engineering principles, API development, and database systems (SQL/NoSQL) is mandatory to bridge the gap between data science and production software. Crucially, successful candidates possess excellent problem-solving abilities, the capacity to navigate ambiguity, and the communication skills to explain complex technical concepts to diverse audiences. For those passionate about shaping the future with intelligent systems, Senior AI Engineer jobs offer a challenging and rewarding career path at the cutting edge of innovation.