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3700 Job Offers

Principal Applied Researcher AI/NLP
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United States
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Not provided
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PointClickCare
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Principal Software Engineer (Java)
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Canada , Mississauga
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PointClickCare
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Principal Applied Researcher AI/NLP
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United States
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PointClickCare
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Principal Firmware Validation Manager
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India , Bangalore
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Microsoft Corporation
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Principal AI Engineer (Autonomous Agent)
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Canada , Mississauga
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PointClickCare
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Principal Salesforce Architect
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Canada , Mississauga
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Not provided
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PointClickCare
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Principal Salesforce Architect
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United States
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PointClickCare
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Technical Leader - Principal Mechanical Design Engineer
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United States , Chicago
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135000.00 - 165000.00 USD / Year
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Nemera
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Principal Environmental, Social, Governance (ESG) Program Manager
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United Kingdom , London
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New Relic
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Principal Product Manager
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United States , Redmond
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Principal UX Research Manager
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Lead a team of UX Researchers at Microsoft AI, shaping next-generation AI products like Copilot and Bing. This player-coach role in Redmond requires a PhD/Master's and 5-6+ years of experience in HCI or related fields. You'll drive product strategy through mixed-methods research, fostering cross-...
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United States , Redmond
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163000.00 - 296400.00 USD / Year
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Microsoft Corporation
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Principal Portfolio Launch Excellence, International
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Lead the commercial launch of innovative Screening and Precision Oncology solutions in international markets. This hands-on role in Zug requires 12+ years of cross-functional leadership in healthcare/life sciences. You will drive launch readiness, ensuring market access and execution through expe...
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Switzerland , Zug
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Exact Sciences
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Sr. Principal Medical Development Director
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Seeking a Sr. Principal Medical Development Director to provide clinical and translational leadership for our oncology strategies. This remote or San Diego-based role requires an M.D./D.O. with oncology fellowship and molecular expertise to drive diagnostic test development from design to regulat...
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United States , San Diego; Remote
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280000.00 - 420000.00 USD / Year
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Exact Sciences
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Principal Clinical Molecular Geneticist
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United States , Phoenix
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149000.00 - 253000.00 USD / Year
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Exact Sciences
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Principal Screening Medical Officer
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United States , Madison
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260000.00 - 348000.00 USD / Year
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Exact Sciences
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Principal International Operations
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Lead operational readiness for new product launches and market entries in Zug. This pivotal role requires 8+ years in pharma/biotech operations, with expertise in cross-functional collaboration and strategic partner management. Drive scalable infrastructure and process efficiency to support globa...
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Switzerland , Zug
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Exact Sciences
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Principal Product Manager
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Lead AI-powered innovation for the Windows Shell, including the Start Menu and Taskbar, in Redmond. As a Principal Product Manager, you'll use the JTBD framework and deep UX/UI expertise to shape intuitive experiences for millions. This role requires 8+ years in product management and hands-on ex...
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United States , Redmond
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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IT Principal Product Manager
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Lead complex healthcare IT product initiatives as a Principal Product Manager. This senior role requires 12+ years of IT experience, including 8+ in a medical/hospital setting. You will define roadmaps, own KPIs, and guide engineering teams in Englewood, US. We offer robust benefits including med...
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United States , Englewood
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61.74 - 91.84 USD / Hour
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American Nursing Care
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Principal Software Engineer
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Lead AI-native data protection platform design at Microsoft Purview. Drive 0→1 initiatives in Hyderabad, focusing on multi-tenant SaaS, automation, and secure-by-default experiences for SMB/SMC growth. Leverage 10+ years of product management expertise in cybersecurity and distributed systems.
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India , Hyderabad
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Microsoft Corporation
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Senior Principal Software Engineer
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Lead groundbreaking SASE technology as a Senior Principal Software Engineer in Santa Clara. Design and develop high-performance networking data path software using C and DPDK. This technical leadership role requires 10+ years of experience in system software and data plane architecture. Drive ful...
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United States , Santa Clara
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170000.00 - 277000.00 USD / Year
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Palo Alto Networks
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About the Principal role

A Principal role represents a senior leadership position found across various industries, from construction and engineering to technology and product management. Individuals in these jobs are trusted with high-level strategic oversight, complex problem-solving, and driving significant organizational impact. Unlike entry-level or mid-career positions, Principal jobs typically require a deep well of specialized expertise, a proven track record of leadership, and the ability to influence direction without direct managerial authority over every team member.

In a professional context, a Principal is often the highest individual contributor or a senior team lead responsible for shaping the vision and execution of critical initiatives. For example, in design and construction sectors, a Principal Designer focuses on risk management from the earliest stages of a project. They ensure that health and safety regulations, such as the CDM Regulations 2015, are integrated into the design process, mitigating hazards before construction begins. This involves leading cross-functional coordination, conducting design reviews, and ensuring a seamless handover to contractors.

In technology and business strategy, Principal Product Managers own the end-to-end lifecycle of complex service portfolios or product lines. They are responsible for defining strategy, developing business cases, and launching innovative offerings that drive customer adoption and revenue growth. These roles demand a data-driven approach to decision-making, strong cross-functional leadership, and the ability to influence executives and stakeholders across engineering, sales, marketing, and customer success teams. Common responsibilities include market analysis, competitive benchmarking, pricing strategy, and building go-to-market plans.

Typical skills required for Principal jobs include exceptional communication and presentation abilities, strategic thinking, and a high degree of autonomy. Candidates usually possess a bachelor’s or master’s degree in a relevant field, combined with significant experience—often eight or more years in a related domain. Technical proficiency is critical, whether in understanding network security, cloud infrastructure, or construction regulations. Soft skills such as negotiation, mentorship, and the ability to drive alignment in matrixed organizations are equally important.

Ultimately, Principal jobs are about leading from the front, solving the most challenging problems, and setting the standard for excellence within an organization. Whether mitigating risk on a construction site or defining the future of a software platform, these professionals are integral to driving meaningful, lasting results.