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Principal Engineer - AI/ML United States Jobs (Hybrid work)

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Principal Product Support Engineer
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Seeking a Principal Product Support Engineer to provide expert-level technical support for HPE's Private Cloud, serving federal customers. This role requires US Citizenship with an active Secret clearance, 10+ years of experience, and cloud certifications. You will lead troubleshooting, collabora...
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United States , Oklahoma City; Dallas; Houston
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152000.00 - 349000.00 USD / Year
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Hewlett Packard Enterprise
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Principal Electrical Engineer
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Lead the electrical design of next-generation neuromodulation implants as a Principal Electrical Engineer. This Plymouth-based role requires 10+ years of AIMD experience, focusing on ultra-low-power analog, stimulation, and telemetry circuits. You will drive the full development lifecycle for Cla...
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United States , Plymouth
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Not provided
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Blackrock Neurotech
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Principal Human Factors Engineer
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Lead Human Factors strategy for medical devices in Philadelphia, ensuring safety and regulatory compliance (FDA/IEC). Apply 10+ years of experience to guide design teams and mentor juniors. Travel up to 30% and shape products from early research to final validation.
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United States , Philadelphia
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Not provided
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Delve
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Principal Security Engineer
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Lead our security architecture as a Principal Security Engineer in San Francisco. You will design scalable, secure systems in AWS, embedding security into the SDLC and CI/CD pipelines. This high-impact role requires 10+ years of expertise in cloud security, application security (OWASP), and zero-...
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United States , San Francisco
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136000.00 - 241000.00 USD / Year
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Ethos
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Principal Software Engineer
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Lead the architecture of our next-gen AI claims platform as a Principal Software Engineer in New York. You will design scalable systems handling millions of documents daily, leveraging LLMs and unstructured data. This role requires 10-15+ years of experience, expert Python skills, and a proven tr...
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United States , New York
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270000.00 - 300000.00 USD / Year
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EvolutionIQ
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Sr. Principal Software Engineer - Applied AI
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Lead our Applied AI initiatives as a Principal Software Engineer in Seattle. You will apply Generative AI and Agentic systems to solve high-impact business challenges at scale. This role requires deep expertise in LLMs, cloud services, and mentoring teams. We offer comprehensive benefits, flexibl...
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United States , Seattle
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277391.00 - 342391.00 USD / Year
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Highspot
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Sr. Principal Software Engineer – Search & Recommendation
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Lead the design of intelligent search and recommendation systems at Highspot. This senior principal role requires 8+ years of expertise in ML, information retrieval, and large-scale platforms. Drive technical strategy, mentor engineers, and shape discovery for millions of users from our Seattle o...
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United States , Seattle
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277391.00 - 342391.00 USD / Year
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Highspot
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Principal Cloud Infrastructure Engineer
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Lead the evolution of our cloud infrastructure and developer platform at Highspot in Seattle. We seek an expert with 15+ years' experience, deep AWS/Azure and Kubernetes mastery, and a passion for building secure, scalable platforms. Empower product teams by designing self-service tools and drivi...
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United States , Seattle
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188696.00 - 282609.00 USD / Year
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Highspot
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Principal Engineering Manager - Applied AI
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Lead a cutting-edge Applied AI team in Seattle, focusing on Generative and Agentic AI systems. You will need 2+ years in Generative AI and 4+ years as an engineering manager. This role offers comprehensive benefits, flexible PTO, and a chance to shape Highspot's AI platform.
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United States , Seattle
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240870.00 - 297652.00 USD / Year
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Highspot
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Sr. Principal Engineer, Interact Analytics Experiences
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Lead the architecture and innovation of Highspot's in-app analytics platform in Seattle. This senior principal engineer role requires 10+ years of expertise in OLAP, query engines, and scalable frontend frameworks (TypeScript/React). You will drive the full analytics stack, from backend performan...
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United States , Seattle
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277391.00 - 342391.00 USD / Year
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Highspot
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Principal Backend Engineer, Forward Deployed
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Lead high-impact AI solutions as a Principal Forward Deployed Engineer. You'll architect and deploy end-to-end systems using Python, cloud platforms, and modern AI tools. This hybrid role blends technical strategy with client partnership in key US tech hubs. Enjoy a bonus and equity in a role sha...
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United States , Austin; New York; San Francisco Bay Area; Washington DC–Baltimore
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225000.00 - 370000.00 USD / Year
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Invisible Technologies
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Principal Software Engineer
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Lead complex backend projects as a Principal Software Engineer at LogRocket in Boston or NYC. Design highly available distributed systems and machine learning pipelines using modern cloud technologies. Enjoy catered lunches, unlimited vacation, generous stock options, and a collaborative, craft-f...
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United States , Boston or NYC
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225000.00 - 260000.00 USD / Year
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LogRocket
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Principal Engineer / Director, Motion Planning
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Lead the development of safety-critical motion planning for autonomous vehicles in Santa Clara. This senior role requires 7-10 years of experience building robust, data-driven systems and a proven record in deep learning (C++/Python). You will manage a team, scale ML pipelines, and drive innovati...
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United States , Santa Clara
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200000.00 - 280000.00 USD / Year
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PlusAI
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Principal Engineer
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Lead the architecture and modernization of a large-scale, cloud-native SaaS platform. This senior role requires 10+ years in SaaS, deep expertise in .NET, AWS serverless, and system design. You will guide engineering teams and drive scalability from New York.
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United States , New York
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175000.00 - 185000.00 USD / Year
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Resourceful Talent Group
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Principal R&D Engineer
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Lead wireless technology innovation as a Principal R&D Engineer at Silvus in Los Angeles. This role requires a U.S. Citizen with an advanced degree and 10+ years of experience, including technical project leadership. You will oversee the full development cycle of cutting-edge wireless systems, fr...
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United States , Los Angeles
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180000.00 - 250000.00 USD / Year
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Silvus Technologies (International)
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Principal FPGA / RTL Design Engineer - Signal Processing
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Lead FPGA/RTL design for cutting-edge MIMO wireless systems in Los Angeles. This senior role requires 10+ years of expertise in Verilog/SystemVerilog, DSP, and Xilinx Vivado for full-cycle development. You will architect and implement signal processing algorithms, ensuring timing closure and hard...
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United States , Los Angeles
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165000.00 - 250000.00 USD / Year
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Silvus Technologies (International)
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Principal FPGA / RTL Design Engineer - Signal Processing
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Lead FPGA/RTL design for advanced wireless systems in Irvine. Utilize 10+ years of signal processing expertise to implement DSP algorithms from concept to deployment. This role requires deep Verilog/SystemVerilog skills and U.S. citizenship for government projects. Join a team developing cutting-...
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United States , Irvine
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165000.00 - 250000.00 USD / Year
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Silvus Technologies (International)
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Principal FPGA / RTL Design Engineer
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Join Silvus Technologies as a Principal FPGA/RTL Design Engineer in Irvine. You will architect and implement advanced digital signal processing for cutting-edge MIMO wireless systems. This role requires 10+ years of RTL/FPGA expertise using Verilog/SystemVerilog and Xilinx Vivado. U.S. Citizenshi...
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United States , Irvine
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165000.00 - 250000.00 USD / Year
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Silvus Technologies (International)
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Principal Embedded Software Engineer
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Lead embedded software development for advanced MANET radios and research projects in Irvine. This senior role requires 8+ years of C programming and Linux kernel driver expertise. You will design MAC protocols, security features, and BSPs for ARM/RISC-V systems, ensuring compliance with NIST FIP...
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United States , Irvine
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165000.00 - 215000.00 USD / Year
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Silvus Technologies (International)
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Principal Android Engineer
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Lead technical direction and innovation for Android applications used by over 700k daily users. As a Principal Engineer in Boston, you'll architect scalable systems with Kotlin, Compose, and modern Android frameworks. Drive excellence, mentor teams, and shape cross-platform strategy in a mission-...
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United States , Boston
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189000.00 - 210000.00 USD / Year
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SimpliSafe
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Embark on a leadership career at the pinnacle of technical innovation by exploring Principal Engineer - AI/ML jobs. A Principal Engineer in Artificial Intelligence and Machine Learning is a strategic visionary and a technical master, responsible for setting the technological direction for an organization's most ambitious AI initiatives. This is not an individual contributor role in the traditional sense; it is a force multiplier, blending deep hands-on expertise with architectural oversight, mentorship, and cross-functional leadership to transform complex business problems into scalable, intelligent solutions powered by AI. Professionals in these senior roles typically bear a comprehensive set of responsibilities. They lead the architectural design and long-term strategy for AI/ML systems, ensuring they are robust, scalable, and aligned with business objectives. A key part of their duties involves conducting research and development to evaluate and integrate state-of-the-art algorithms and models, pushing the boundaries of what is technically possible. They provide technical leadership and mentorship to engineering teams, elevating the entire organization's capabilities through code reviews, best practice dissemination, and setting high standards for quality and innovation. Principal Engineers are also crucial in driving the entire machine learning lifecycle, from data acquisition and pipeline creation to model training, deployment, monitoring, and continuous iteration in production environments. They act as a bridge, communicating complex technical concepts to non-technical stakeholders and collaborating with product managers, data scientists, and business leaders to ensure successful project outcomes. Furthermore, they are often tasked with establishing technical governance, making critical stack and tooling decisions, and identifying and mitigating technical risks. To qualify for Principal Engineer - AI/ML jobs, candidates must possess a formidable combination of education, experience, and skills. Typically, a Master's or Ph.D. in Computer Science, Statistics, or a related field is expected, coupled with 10+ years of progressive software engineering experience, with a significant portion dedicated to AI/ML. A deep, practical understanding of machine learning frameworks like TensorFlow or PyTorch is essential, as is proficiency in programming languages such as Python, Java, or Scala. Expertise in cloud platforms (AWS, GCP, Azure) and MLOps practices for automating the ML lifecycle is a standard requirement. Beyond technical prowess, successful candidates demonstrate exceptional leadership, strategic thinking, and communication skills. They have a proven track record of architecting and delivering complex, large-scale AI systems into production and possess the ability to mentor senior engineers and influence technical strategy across an organization. If you are ready to shape the future of technology and lead from the front, discovering the right Principal Engineer - AI/ML jobs is your next critical step.

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