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Principal United States Jobs (On-site work)

646 Job Offers

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Principal Design Engineer, Analog Mixed-Signal (AMS)
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Lead the end-to-end architecture of a custom AMS ASIC for an implantable neural interface in Alameda, CA. Requires 10+ years of AMS IC design, multiple tapeouts, and low-noise ultra-low-power expertise.
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Epia Neuro
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Principal Engineer, Electrical (R5909)
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Shield AI seeks a Principal Electrical Engineer in San Diego to own flight-critical avionics and circuit design for V-BAT aircraft. Requires 10+ years of EE experience, full-cycle hardware development, and strong mentorship skills.
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210000.00 - 310000.00 USD / Year
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Shield AI
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Principal Ecosystem Partner Manager
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Lead strategic partnerships with CPU, ODM and OEM ecosystems as Principal Ecosystem Partner Manager at Astera Labs in San Jose. Requires 7+ years in semiconductor or data center infrastructure, PCIe/CXL knowledge, and strong partner program experience.
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Astera Labs
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Principal Engagement Manager
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Lead professional services engagements for Blitzy's AI-native platform in Cambridge, US. Drive customer success, manage large-scale projects, and collaborate cross-functionally. Bonus and equity offered.
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Blitzy
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Sr. Principal Scientist - QA
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Lead QA oversight for radioligand drug product manufacturing in Indianapolis. Requires 5+ years of pharma QA/QC experience and a science-related degree. On-site role ensuring GMP compliance and batch disposition.
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Lilly
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Principal Solutions Consultant
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Lead complex FinTech solutions consulting as Principal Solutions Consultant in New York. Requires 8+ years in sales engineering, architectural framing for frontier use cases, and mentoring. Drive strategic partner outcomes.
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Gen
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Principal Chemist – GMP Analytical Method Development and Testing Lilly Medicine Foundry
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Join Lilly's $4.5B Medicine Foundry as Principal Chemist in Carmel, IN. Develop and validate HPLC/UPLC and LC-MS methods in a GMP lab supporting cleaning validation. Requires M.S. with 5+ years or B.S. with 8+ years pharma experience.
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Lilly
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Principal Engineer, SSD Systems Design
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Lead SSD system design and architecture at Micron in Longmont, CO. Requires 6+ years in SSD development, deep PCIe/NVMe expertise, and strong cross-functional leadership. Shape next-gen storage solutions.
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United States, Longmont-MAX- Office
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Micron
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Senior Principal Robotics Hardware Architect
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Senior Principal Robotics Hardware Architect role at Analog Devices in Wilmington, MA. Lead enabling technology for humanoid, mobile and collaborative robots, from architecture to working hardware. Requires 10+ years in robotics and deep semiconductor system design expertise.
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Analogdevices
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Principal Geologist
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Endurance seeks a Principal Geologist in Seattle to lead subsea geothermal drilling and site characterization. Requires 4+ years in subsurface fluids, drilling ops experience, and $10M+ budget management.
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Endurance Energy
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Principal Manufacturing Process Engineer
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FormFactor seeks a Principal Manufacturing Process Engineer in Farmers Branch, TX to optimize photolithography and etch processes in high-volume semiconductor manufacturing. Requires 5+ years experience with SPC, DOE, and CAPA expertise.
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Formfactor
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Principal Solutions Architecture
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On-site Systems Architect role in Fort Walton Beach, FL requiring 5+ years of USASOC/AFSOC and tactical communications experience. Integrate CDS, tactical networks, and C2 solutions while providing hands-on training and system support.
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Clarity Innovations
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Principal Talent Partner - Executive Search
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Lead executive search as a Principal Talent Partner in Coppell, TX. Requires 7+ years recruiting complex technical roles, strong sourcing and stakeholder influence skills. ESOP, 401K, bonus, 17 PTO days.
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Rosendin
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Principal GTM Recruiter
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Quantcast seeks a Principal GTM Recruiter in New York with 10+ years of recruiting experience, including 6+ years in GTM roles. Requires agency background, strong sourcing skills, and a network across media, advertising, and SaaS.
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Quantcast
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Principal Automation Engineer
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Lead Site Reliability Engineering for NYC's automation platforms as Principal Automation Engineer in Brooklyn. Oversee CI/CD pipelines, IaC, and incident response while mentoring DevOps engineers. Master's or bachelor's plus 3-4 years IT experience required.
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City of New York
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Principal Human Resources Analyst, City College of San Francisco (1246)
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Lead HR operations at City College of San Francisco as Principal Human Resources Analyst. Requires a bachelor's degree, 5 years of HR experience, and expertise in recruitment, classification, or benefits.
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City and County of San Francisco
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Principal Systems Engineer, Signal-Path Performance & Modeling
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Lead signal-path architecture for silicon photonics at Neurophos in Austin. Requires MS/PhD, 7+ years in communication systems, link-budget modeling, and DSP expertise. Top benefits and equity.
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Neurophos
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Principal Software Engineer
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UiPath seeks a Principal Software Engineer in Bellevue to architect large-scale cloud services and AI-native systems. Requires 10+ years building commercial applications, distributed systems expertise, and a founder mindset.
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UiPath
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Principal Thermal Engineer - Aircraft Avionics & Thermal Systems (R3930)
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Lead thermal architecture for UAV avionics at Shield AI in Seattle. Requires 12+ years in electronics thermal engineering, CFD expertise (FloEFD, Icepak), and strong heat transfer fundamentals. Shape next-gen AI aircraft systems.
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250000.00 - 350000.00 USD / Year
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Shield AI
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Principal Mechanical Engineer / Systems Engineer
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Lead mechanical architecture for HaloBraid, a first-of-its-kind robotic braiding device in Cambridge, MA. Requires 10+ years in electromechanical product development, CAD review, DFM/DFA, and pilot-to-production delivery. Equity, full benefits, unlimited PTO.
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HaloBraid
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About the Principal role

A Principal role represents a senior leadership position found across various industries, from construction and engineering to technology and product management. Individuals in these jobs are trusted with high-level strategic oversight, complex problem-solving, and driving significant organizational impact. Unlike entry-level or mid-career positions, Principal jobs typically require a deep well of specialized expertise, a proven track record of leadership, and the ability to influence direction without direct managerial authority over every team member.

In a professional context, a Principal is often the highest individual contributor or a senior team lead responsible for shaping the vision and execution of critical initiatives. For example, in design and construction sectors, a Principal Designer focuses on risk management from the earliest stages of a project. They ensure that health and safety regulations, such as the CDM Regulations 2015, are integrated into the design process, mitigating hazards before construction begins. This involves leading cross-functional coordination, conducting design reviews, and ensuring a seamless handover to contractors.

In technology and business strategy, Principal Product Managers own the end-to-end lifecycle of complex service portfolios or product lines. They are responsible for defining strategy, developing business cases, and launching innovative offerings that drive customer adoption and revenue growth. These roles demand a data-driven approach to decision-making, strong cross-functional leadership, and the ability to influence executives and stakeholders across engineering, sales, marketing, and customer success teams. Common responsibilities include market analysis, competitive benchmarking, pricing strategy, and building go-to-market plans.

Typical skills required for Principal jobs include exceptional communication and presentation abilities, strategic thinking, and a high degree of autonomy. Candidates usually possess a bachelor’s or master’s degree in a relevant field, combined with significant experience—often eight or more years in a related domain. Technical proficiency is critical, whether in understanding network security, cloud infrastructure, or construction regulations. Soft skills such as negotiation, mentorship, and the ability to drive alignment in matrixed organizations are equally important.

Ultimately, Principal jobs are about leading from the front, solving the most challenging problems, and setting the standard for excellence within an organization. Whether mitigating risk on a construction site or defining the future of a software platform, these professionals are integral to driving meaningful, lasting results.