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Cybersecurity – Senior Information System Security Manager Jobs

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Information Systems Security Officer Level 2
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United States , Annapolis Junction
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Columbia Technology Partners
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Senior Cybersecurity Analyst, Threat Hunter
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United States , Westbrook, Maine
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120000.00 - 140000.00 USD / Year
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IDEXX
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Senior Information Assurance Specialist
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United States , Fort Eustis, Virginia; Fort Leavenworth, Kansas
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Barbaricum
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Senior Cybersecurity Specialist
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United States , Fort Belvoir
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Barbaricum
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Cyber Security Compliance Manager
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United States , Orlando
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ThreatLocker
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Operational Technology (OT) Cyber Security Engineer
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United Kingdom , Stockton-on-Tees
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Risktec Solutions
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Manager, Security Architecture and Cloud
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United States , Princeton
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140000.00 - 165000.00 USD / Year
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Renner Brown
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IT Program Manager – Enterprise Modernization & Cybersecurity
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United States , Mechanicsburg
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Rackner
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Senior Cybersecurity Engineer
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United States , Dayton
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Rackner
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Senior Security Engineer
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United States
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Orbis Consultants
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Senior Security Engineer
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United States
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Orbis Consultants
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Senior Cloud Security Engineer
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United States , New York City
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Orbis Consultants
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Senior Cloud Security Engineer
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United States , New York
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Orbis Consultants
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Senior Cybersecurity Engineer
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United States , Hanscom AFB, Bedford, MA
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MAINSAIL Group
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Senior Systems Engineer
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United States , Fairfield
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Kyber Security
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Security Architect
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Herzliya
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Infinidat
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Senior Security Engineer
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United States , Aguadilla
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Hewlett Packard Enterprise
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Senior Compliance Program Manager
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United States , San Francisco
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116100.00 - 186500.00 USD / Year
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Atlassian
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Security Manager
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United States , New Holland
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Robert Half
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Senior Detection Engineer
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Singapore , Singapore
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Marriott Bonvoy
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Explore high-impact Cybersecurity – Senior Information System Security Manager jobs, a critical leadership role at the intersection of security governance, risk management, and technical oversight. Professionals in this senior capacity are entrusted with the ultimate responsibility for the security posture of an organization's classified or sensitive information systems. They serve as the designated authority, ensuring that all systems operate within stringent regulatory and policy frameworks to protect national security or critical corporate data from sophisticated threats. A Senior ISSM typically oversees the entire lifecycle of information system security. Central to their role is the management and implementation of governance frameworks like the Risk Management Framework (RMF) or other compliance models. They lead the assessment and authorization (A&A) process, guiding systems through certification and accreditation. Beyond initial approval, they establish and manage robust continuous monitoring programs to ensure ongoing compliance, swiftly identifying and mitigating vulnerabilities. Their day involves directing security assessments and audits, analyzing security controls, and authorizing key system security plans and documentation. They are also responsible for translating high-level regulatory directives into actionable enterprise-wide security policies, standards, and procedures. This position demands a unique blend of deep technical knowledge, managerial acumen, and strategic vision. Senior ISSMs provide technical leadership and mentorship to cybersecurity teams, fostering a culture of security awareness. They act as a key liaison between technical teams, program managers, and external accrediting officials, effectively communicating risks and requirements. Exploring the evolving threat landscape and industry best practices to adapt security postures is a constant duty. Typical requirements for these senior-level jobs include extensive experience (often 5+ years) in cybersecurity, with a proven track record in implementing security frameworks and managing complex system authorizations. Advanced professional certifications such as CISSP, CISM, or GSLC are standard prerequisites, validating expertise at the Information Assurance Management (IAM) Level III. Given the sensitive nature of the work, candidates must typically be eligible for and maintain a high-level government security clearance. Success hinges on strong analytical skills for risk-based decision making, exceptional communication abilities for reporting and briefing, and a comprehensive understanding of security controls across operating systems, networks, and applications. For seasoned cybersecurity leaders seeking to protect vital assets and shape organizational security strategy, Senior Information System Security Manager jobs represent the pinnacle of a career in information assurance and compliance leadership.

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