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Apogee Therapeutics Logo Apogee Therapeutics · Research and Development

Vice President, Inflammatory and Immune Disease Biomarker Development

United States 320000.00 - 355000.00 USD / Year · Job Posted January 19, 2026
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Job Description

We are seeking a highly experienced and motivated individual to lead our biomarker efforts in the field of inflammatory and immune diseases, with a focus on atopic dermatitis, asthma, COPD and EOE. Reporting to the Senior Vice President – Research and Translational Medicine, the successful candidate will be responsible for overseeing the strategy and implementation of all our translational clinical and preclinical biomarker programs from early but particularly late-stage development including Phase 3 trials and BLA-readiness for all our assets.

Job Responsibility

  • Lead the strategic planning and execution of biomarker discovery and development programs for inflammatory and immunology diseases, focusing on atopic dermatitis, asthma, COPD and EOE and particularly late-stage clinical development
  • Develop and articulate the late-stage clinical and post-launch strategic vision for the biomarker programs to internal and external stakeholders
  • Collaborate with internal and external stakeholders to integrate our biomarker discovery and development efforts into our development programs, including clinical trials and BLAs
  • Oversee the Biomarker Discovery and Development team to drive efforts through a combination of in vitro/in vivo and in silico data analyses, in house and in collaboration with external partners
  • Together with the Senior Director-Biomarker Discovery and Development develop and implement biomarker strategies to demonstrate the clinical utility of novel biomarkers and the distinction of patient populations and responders as well as additional indications
  • Stay current on emerging trends and technologies in biomarker discovery and development, and implement best practices to ensure the success of our programs
  • Provide strategic input and leadership to cross-functional program and functional teams to drive the development of novel, innovative therapies for inflammatory and immunology diseases

Requirements

  • PhD or MD in a relevant scientific discipline
  • At least 15 years of track-record in senior leadership roles in biomarker discovery and development, preferably in the field of inflammatory and immunology diseases
  • Proven success in leading biomarker discovery programs from ideation to clinical validation
  • Focused understanding on late-stage clinical development including Phase 3 trials with biologics and BLAs is required
  • Experience in I&I, atopic dermatitis, asthma, COPD and/or EOE a plus
  • Excellent communication skills and ability to articulate and communicate complex strategic vision
  • Deep hands-on knowledge of the antibody development process and regulatory requirements for biomarkers in clinical trials and for BLA-submissions
  • Strong preference for candidates with late stage clinical and post launch experience
  • Expertise in collaborating with external partners and key opinion leaders
  • Strong leadership and communication skills fully aligned with our C.O.R.E. values
  • Position requires up to 30% travel including mandatory in-person attendance at All Hands meetings typically held twice per year as well as travel to Apogee offices in Boston and San Francisco
  • At least 4 years of experience working in a biotech or pharmaceutical company

Nice to have

  • Experience in I&I, atopic dermatitis, asthma, COPD and/or EOE
  • Late stage clinical and post launch experience

What we offer

  • Market competitive compensation and benefits package, including base salary, performance bonus, equity grant opportunities, health, welfare & retirement benefits
  • Three weeks PTO, two one-week company-wide shutdowns a year and dedicated paid sick leave
  • Commitment to growing you professionally and providing access to resources to further your development
  • Apogee offers regular all team, in-person meetings to build relationships and problem solve
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