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Vice President Clinical Operations

Denmark, Hørsholm Kommune · Job Posted June 29, 2026
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Job Description

Gubra is seeking a Senior Director or VP, Clinical Operations to lead the design, execution, and oversight of its growing early-to-mid-stage clinical trial portfolio. This role is a senior leadership appointment within the Development leadership team and reporting into the Chief Medical and Development Officer. You will own clinical operations strategy and delivery across Gubra's internal development programmes across multiple therapeutic areas, with responsibility for building and leading the clinical operations function from the ground up.

Job Responsibility

  • Build and lead the clinical operations function, including hiring, structuring, and developing an internal team as the pipeline grows across Phase I and II clinical trials
  • Own end-to-end operational delivery of Gubra's clinical trial portfolio, including GUB-UCN2 and future internal candidates, from study start-up through to close-out
  • Define and execute clinical operations strategy in close cross-functional partnership
  • Select, manage, and oversee performance of CROs and other external vendors, ensuring quality, timeline, and budget delivery across all studies
  • Establish robust clinical trial management systems, including vendor oversight, SOPs, and quality frameworks appropriate for a scaling, GCP-compliant clinical organisation
  • Manage clinical operations budgets and resourcing plans, providing regular progress and risk reporting to the executive team
  • Ensure inspection-readiness and compliance with ICH-GCP, EU Clinical Trials Regulation, and other applicable regulatory frameworks across all studies
  • Support investor and board-facing communications on clinical progress in partnership with the CDMO, CEO and Investor Relations

Requirements

  • 10+ years' experience in clinical operations within biotech or pharma, including significant senior leadership experience (Director/VP level)
  • Proven track record of building or scaling a clinical operations function, ideally within a growing or transitioning biotech organisation
  • Direct experience managing early-phase (Phase 1/2) clinical trials, including first-in-human studies
  • Strong working knowledge of ICH-GCP, EU Clinical Trials Regulation, and clinical trial application processes in Europe and the USA
  • Fluent English required
  • Willingness to be based in the greater Copenhagen area or Basel area, and/or ability to travel to Gubra offices in Denmark on a regular basis
  • Experience working with or alongside large pharma partners on co-developed or licensed clinical programmes is highly advantageous
  • Background in metabolic disease, obesity, or peptide therapeutics is a strong plus, though not essential
  • Demonstrated ability to operate at both strategic and hands-on operational levels in a lean, fast-scaling organisation

Nice to have

  • Experience working with or alongside large pharma partners on co-developed or licensed clinical programmes
  • Background in metabolic disease, obesity, or peptide therapeutics
  • Demonstrated ability to operate at both strategic and hands-on operational levels in a lean, fast-scaling organisation

What we offer

  • A senior leadership role at a high-growth, NASDAQ-listed techbio with strong financial backing and a differentiated clinical pipeline
  • The opportunity to build a function from the ground up during a defining period of Gubra's expansion into clinical-stage development
  • Direct exposure to pharma and biotech partnerships and a fast-advancing portfolio within metabolic diseases and beyond
  • Competitive compensation
  • Equity participation
  • Hybrid working model based in Hørsholm, Denmark or Basel, Switzerland
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