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Vice President and Head of Information Technology

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Cabaletta Bio Inc

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Location:
United States , Philadelphia

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Contract Type:
Not provided

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Salary:

Not provided

Job Description:

The Vice President and Head of Information Technology will be responsible for designing, implementing, and managing the company’s entire IT infrastructure and strategy. This role will lead the development of scalable, secure, and compliant systems that facilitate innovation and reliably support operational excellence across all functions.

Job Responsibility:

  • Develop and execute a forward-looking IT strategy aligned with business priorities and regulatory requirements
  • Partner closely with executive leadership to identify and implement technology solutions that drive efficiency and innovation
  • Build and lead a high-performing IT team, fostering a culture of service, agility, and continuous improvement
  • Architect and deploy scalable infrastructure across cloud, network, and on-premise environments
  • Collaborate with functional leads to guide the selection and implementation of reliable and efficient enterprise systems (e.g., ERP, LIMS, QMS, HRIS, CRM) to support scientific, clinical, technical operations, commercial and corporate functions
  • Ensure system interoperability, data integrity, and performance across the organization
  • Establish and maintain robust cybersecurity frameworks and data protection protocols
  • Ensure IT systems and practices comply with GxP, HIPAA, GDPR, and other relevant regulations, where applicable
  • Lead IT audits, risk assessments, and incident response planning, maintaining clear traceability
  • Provide responsive and proactive IT support to all departments, including R&D, clinical, regulatory, and finance
  • Prioritize investments based on value, risk, and life cycle phase in alignment with corporate strategy
  • Manage IT budgets, vendors, and service level agreements
  • Drive automation, analytics, and digital transformation, and AI initiatives to enhance productivity and scalability
  • Develop, engage, and collaborate in change management practices for updates and changes

Requirements:

  • Bachelor’s or Master’s degree in Computer Science, Information Systems, or related field
  • 10+ years of progressive IT leadership experience, with at least 3 years in biotech, pharma, or life sciences
  • Proven success in building IT infrastructure and teams from the ground up in a high-growth environment with preference for direct experience in supporting autologous cell therapy launch and commercialization
  • Expertise in SaaS and cloud platforms (e.g., AWS, Azure), cybersecurity, and enterprise applications
  • Experience with GxP systems, 21 CFR Part 11, GAMP 5, EU Annex 9, ICH Q9 and other regulatory compliance systems in a commercial biotech or clinical setting
  • Strong leadership, communication, and cross-functional collaboration skills with a client focused, partnering approach
  • Strong team orientation and passion for continuous self-development
What we offer:

health and retirement, PTO, and stock option plans

Additional Information:

Job Posted:
December 06, 2025

Work Type:
Hybrid work
Job Link Share:

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