Translational Pharmacology & Microbiology Scientist Job at Eligo Bioscience (Paris)

Job Description

As part of the Translational Pharmacology team, you will contribute to the generation of pivotal preclinical data to support the development of Eligo’s programs towards the clinic. You will join a team of translational scientists with strong experience in the set up and execution of in vitro, ex vivo and in vivo models across various fields (immunology, microbiology, molecular biology, pharmacology) to support the preclinical development of Eligo’s programs either internally or in collaboration with external partners. You will report to the translational pharmacology team lead.

Job Responsibility

Design, execute, and oversee hands-on experiments across in vivo (rodents), ex vivo (human or rodent primary cells and tissues), and in vitro (cell lines, bacterial cultures) models, employing diverse cellular biology, immunology, microbiology, and molecular biology techniques
Analyze, interpret, and effectively communicate experimental findings at various meetings involving multidisciplinary teams and/or collaborators
Independently plan experimental paths forward, proactively develop and/or optimize methods, and incorporate new technology/techniques into practice
Prepare comprehensive reports and presentation materials as necessary, and maintain meticulous experimental documentation in electronic lab notebooks in accordance with Eligo’s working practice
Contribute to scientific review meetings and assist in drafting relevant sections of regulatory documents as needed
Foster a collaborative and supportive environment, aiding in the development and well-being of fellow team members while also participating in general lab support operations
Stay aware of recent advancements in the field through literature review and dissemination of data via presentations at scientific conferences when relevant

Requirements

PhD in Microbiology, Molecular Biology, Pharmacology, Immunology or related fields with a track record of publications
Extensive experience in rodent models of host-pathogen/host-microbiote interactions
Postdoctoral training or previous drug discovery or development experience in a biotech or pharmaceutical company setting is highly advantageous
Ability to develop new methods/protocols to support pharmacology studies
Ability to design and run experiments, interpret data, troubleshoot, suggest next steps and identify alternative approaches
Ability to deliver high-quality, consistent results in a timely fashion

Nice to have

Regulatory animal training up to date (study design and/or execution)
Hands-on experience in models of bacterial colonization of the intestine, in particular Clostridia species, or the skin
Experience in molecular biology techniques including but not limited to nucleic acid extraction, qPCR/ddPCR, ELISA, Western Blotting
Hands-on experience in cancer research (cell culture, in vivo and organoïds models)

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Translational Pharmacology & Microbiology Scientist

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