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Enveda Logo Enveda · Research and Development

Translational Medicine Sr. Director

United States 300000.00 - 325000.00 USD / Year · Job Posted February 13, 2026
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Job Description

Join Enveda as a Translational Medicine Sr. Director, ENV-308 in a remote capacity and help us transform natural compounds into life-changing medicines. You will drive biomarker, MOA, and translational strategy for ENV-308, our lead metabolic program in chronic weight management. This role will serve as the connective tissue between preclinical biology, clinical development, and data interpretation, ensuring that human studies are mechanistically informed, biomarker-rich, supportive of commercial positioning, and decision-enabling.

Job Responsibility

  • Own End-to-End Translational Scope for ENV-308: Lead the translational strategy across preclinical and clinical development, with clear ownership for how human biology informs program direction, risk, and value
  • Define Biomarker & MOA Strategy: In collaboration with our MOA and pre-clinical teams, develop and prioritize biomarker and MOA hypotheses, including trial, experiment and assay design to support development decisions and differentiate ENV-308
  • Execute Translational Analyses: Take a hands-on role in analyzing and interpreting clinical, biomarker, and translational data in real time to guide active program decisions
  • Make High-Impact Scientific Judgments: Apply independent scientific judgment to translational decisions that shape the development path and differentiation strategy
  • Lead External Vendor Scientific Oversight: Evaluate, select, and scientifically guide translational and biomarker vendors from feasibility through data delivery
  • Create Decision-Enabling Readouts: Ensure biomarker and translational outputs are high-quality, interpretable, and designed to support clear program decisions
  • Integrate Data into Program and Regulatory Decisions: Synthesize translational and clinical evidence into go/no-go recommendations and contribute translational input to INDs, protocols, and internal reviews
  • Operate as an Asset-Embedded Program Leader: Work as a peer within the program leadership team, embedding translational thinking into clinical design, development sequencing, and portfolio trade-offs

Requirements

  • Ph.D., M.D., or equivalent advanced degree in pharmacology, biomedical sciences, or a related field
  • Minimum of 10 years of experience in translational medicine and / or biomarker strategy within the biotechnology or pharmaceutical industry
  • Minimum of 5 years focused on metabolism / metabolic disease programs with at least some experience in Obesity and Diabetes with a strong scientific grounding in energy balance, appetite regulation, and metabolic adaptation
  • Proven track record of successfully leading translational programs from discovery through clinical development
  • Deep understanding of PK/PD principles, biomarker development, and their application in drug development
  • Strong leadership skills with the ability to influence cross-functional teams and drive strategic initiatives
  • Excellent communication and interpersonal skills, with a demonstrated ability to present complex scientific concepts to diverse audiences
  • Experience with regulatory interactions and knowledge of the regulatory requirements for biomarkers and translational endpoints

What we offer

  • 90% Medical, Dental, Vision
  • 401k Match
  • Flexible PTO
  • Adoption Assistance
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