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Provide expertise, technical and practical support to the toxicology analytical team to facilitate the smooth running of the toxicology laboratory, including instrumentation maintenance and trouble-shooting, validation work and the implementation of new methods.
Job Responsibility:
Ensuring equipment is maintained to specific schedules and monitoring the functioning of the equipment according to SOPs, recognising any problems and taking prompt remedial action to minimise equipment downtime
Calibrating equipment and instrumentation according to SOPs and ensuring up to date records are maintained
Interpret the data and prepare results to contribute to reports
Assisting the toxicology laboratory operational workflow
The appropriate handling and recording of the drug reference standards in compliance with the laboratory’s Home Office controlled drug licence
Delivering training to junior analytical team members when required
Requirements:
Good understanding of drug extraction techniques, notably LLE and SPE
A thorough understanding of chromatographic techniques (such as HS-GC-FID and LC-MS/MS)
Troubleshooting LC-MS/MS instrumentation, both hardware and software
A good understanding of good laboratory practice including ISO17025 and anti-contamination protocols is essential
Technically minded and the ability to problem solve effectively
Familiarity with AB Sciex, Thermo and/or Waters equipment