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Breega Logo Breega · Research and Development

Technician, Cell Engineering

France, Paris · Job Posted January 15, 2026
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Job Description

Brink Therapeutics is a venture-backed biotech company specializing in the development of cutting-edge gene therapy tools. We focus on site-specific recombinases, highly efficient enzymes that enable precise DNA modifications—such as inserting, removing, or inverting DNA sequences—without causing double-strand breaks. These recombinases offer a safer, more precise alternative to existing technologies like CRISPR-Cas9, giving them the potential to revolutionize Cell and Gene Therapies and finally push them over the brink of mass accessibility. As a Cell Engineering Technician, you will provide essential technical support for the development and execution of our in cellulo recombinase assays, with the ultimate goal of characterizing and validating our lead therapeutic recombinase enzyme candidates for efficiency and specificity.

Job Responsibility

  • Implement and perform assay protocols for screening and characterization of recombinases in human cells (cell culture, bacterial cloning, molecular biology, flow cytometry, microscopy, PCR, NGS)
  • Prepare reagents, manage consumable stocks, and ensure the proper functioning and cleanliness of cell culture equipment
  • Perform experimental data acquisition, conduct primary data analysis, and maintain rigorous traceability via an Electronic Lab Notebook (ELN)
  • Communicate technical results and report any experimental anomalies or equipment issues to the supervising scientists

Requirements

  • Bac+2/3 level degree (e.g., French BTS Biotechnologies, BUT Génie Biologique, or Licence Professionnelle in biology/biotechnology)
  • Previous experience (including internships) in molecular or cellular biology, ideally within a research or biotech environment
  • Proficiency in cell culture (immortalized lines
  • experience with primary cells is a plus)
  • Hands-on experience with molecular biology techniques (PCR, qPCR, nucleic acid extraction)
  • Familiarity with transfection methods and basic fluorescence microscopy
  • English - professional working proficiency
  • High attention to detail, strong organizational skills, and a "can-do" attitude in a fast-paced startup environment

Nice to have

  • Experience with Flow Cytometry (FACS)
  • Prior exposure to genome editing tools or viral vector handling

What we offer

  • Competitive salary + benefits package
  • Beautiful, well-equipped offices & labs in the heart of Paris, filled with great plants and great people
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