Staff Bioinformatics Scientist - Genetics Job at Exact Sciences (San Diego)

Job Description

The Staff Bioinformatics Scientist is largely self-driven, working in collaboration with others on one or more projects which are extremely complex in scope. The Staff Bioinformatics Scientist is responsible for successfully leading the planning and execution of projects. This position involves independently making detailed observations, analyzing data that is extremely complex and technical, critically analyzing the data and providing supporting scientific rationale as needed, as well as providing insights into the future direction of the project for successful outcomes. The Staff Bioinformatics Scientist helps develop the timeline and plan for new assignments/projects. As a technical expert with deep knowledge and thorough understanding of the science, the Staff Bioinformatics Scientist provides technical guidance and mentorship to junior scientists in the Research and Development group. Working in a team setting, the Staff Bioinformatics Scientist will be involved in Research and Development projects serving as a technical lead and subject matter expert in exploring, researching, and testing new technologies or providing and developing ideas and concepts to improve or develop processes that add value or establish innovative methods and processes for product development towards development of diagnostic assay products.

Job Responsibility

Conduct comprehensive analyses within several product or technology areas and identify problems and discrepancies
Independently plan and develop algorithms
Independently develop, plan, and analyze results of experiments within several product or technology areas within defined timelines
effectively present and clearly communicate findings at data meetings, group meetings and project team meetings to inform and enable project progression
Critically analyze research/experimental data, interpret the results, and provide insights into the next steps and the direction of the project for successful outcomes
Contribute towards the development of timeline and plan for new assignments/study/projects
Provide technical guidance to junior scientists in project teams
Manage bench-generated data and bioinformatics outputs within high performance computing (HPC) or cloud computing environment
Determine, utilize, and apply methods or technologies effectively and provide ideas for new techniques, when appropriate
Maintain knowledge of technological industry developments that could assist in completion of an assignment or aid in the development of new processes or procedures
Provide scientific rationale when analyzing and interpreting data and provide technical input and participate in decisions affecting project planning and experimental design
Prepare and provide information and data for scientific abstracts/conferences/project meetings/publication
Contribute to the intellectual property portfolio by implementing innovative and creative ideas to solve problems or improve on current methods
Generate, document, and communicate development plans for critical aspects of a project
Develop research plans and experimental outlines to write experimental protocols and perform laboratory experiments
Prepare detailed technical procedures, protocols, and reports
Evaluate impact of nonconforming data to product or process
Identify and address trends in study data
Prepare and approve written reports
Lead identification of areas for process improvements
Maintain lab notebook in a clear, complete, and consistent manner, following all legal, ISO, and QSR requirements
Prepare reports and documentation providing highly technical analysis or summarization of results, outcomes, next steps, and the future direction of the project to functional leader, technical teams/groups, or project teams
Present results and defend scientific ideas and findings at data meetings, group meetings, project team meetings, and/or departmental meetings
critically evaluate scientific data for its merits
lead meetings and help provide directions as a subject matter expert
Demonstrate success in technical proficiency/knowledge, scientific creativity and rigor, collaboration with others, and independent thought and ability to provide insights and defend scientific ideas
Work on problems of extremely complex scope in which analysis of data requires an evaluation of intangible variables
Exercise independent judgment in developing methods, techniques, and evaluation criteria for obtaining solutions
Work on assignments individually and with project team members to meet department and project objectives
Work within project timeframes with successful outcomes on multiple projects and key responsibilities
Act as bioinformatics leader for one or more projects that are complex in scope
Act as subject matter expert in core team and/or cross-functional meetings
Exercise discretion and independent judgement within broadly defined practices and policies in: selecting methods, techniques and evaluation criteria for obtaining and interpreting results
analyzing data and presenting findings in a professional and knowledgeable manner
Promote an open, collaborative environment built on trust to foster positive teamwork
Plan, recommend, and lead activities that account for prioritization of organizational and department goals
Train, guide and mentor research associates and junior level scientists
Organize, present, and convey complex problems or issues
Communicate clearly and frequently with all levels of the organization
including team members, project team members (core and extended), functional managers, clinical lab, and other stakeholders
Create high quality presentations that effectively communicate and tie into a cohesive story the project status and/or experimental results
Apply strength in performing complex analyses and the ability to present data and recommendations to a variety of audiences throughout an organization
Apply qualitative and analytical skills with strong attention to detail
Ability to effectively work on several varied projects at one time, with frequent changing priorities
Demonstrate excellent analytical, problem solving and decision-making skills
Apply sound technical knowledge and ability gained through experience and/or learning
Apply previous knowledge and outcomes to new and valuable problems (able to make predictions based on a deep understanding of the fundamental nature of the inputs into a decision or action)
Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork
Support and comply with the company’s Quality Management System policies and procedures
Maintain regular and reliable attendance
Ability to act with an inclusion mindset and model these behaviors for the organization
Ability to work on a mobile device, tablet, or in front of a computer screen and/or perform typing for approximately 90% of a typical working day
Ability to work on a computer and phone simultaneously
Ability to travel 10% of working time away from work location, may include overnight/weekend travel

Requirements

Ph.D. in bioinformatics, computational biology, computer science, mathematics, or related field
or Master’s degree in bioinformatics, computational biology, computer science, mathematics, or related field plus 4 years of experience in lieu of a Ph.D.
or Bachelor’s degree in bioinformatics, computational biology, computer science, mathematics, or related field plus 6 years of experience in lieu of Ph.D.
8+ years of industry or academia experience in bioinformatics
6+ years of experience in medical device/IVD, biotech, life science or pharmaceutical industry
Demonstrated experience in developing statistical and quantitative methods
Deep knowledge and thorough understanding of molecular biology and/or biochemistry and/or next-generation sequencing (NGS) and genomics
Demonstrated expertise in product/assay research, design, or development
Basic computer skills to include Internet navigation, Email usage, and word processing
Proficient in Microsoft Office to include Excel, Word, and PowerPoint
Demonstrated ability to perform the Essential Duties of the position with or without accommodation

Nice to have

10+ years of experience in medical device/IVD, biotech, life science or pharmaceutical industry
Experience developing and applying advanced linear and non-linear statistical learning methods on complex datasets, including but not limited to supervised and unsupervised machine techniques
Familiarity with applying AI techniques such as deep learning, neural networks, or similar on high dimensional data
Previous experience as a project lead for a team of scientists
Experience in a pharmaceutical or biotech manufacturing environment, preferably in a GMP and/or ISO environment
Previous industry experience in product development or technical support
Experience with genomic databases and software
Whole genome and exome sequencing experience
Background containing a substantial amount of bioinformatics work including troubleshooting
Previous experience working in a molecular diagnostics/clinical laboratory setting

What we offer

paid time off (including days for vacation, holidays, volunteering, and personal time)
paid leave for parents and caregivers
a retirement savings plan
wellness support
health benefits including medical, prescription drug, dental, and vision coverage
bonus eligible

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Staff Bioinformatics Scientist - Genetics

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