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Senior Upstream Scientist

Ireland · Job Posted June 10, 2026
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Job Description

I’m supporting a fast-growing company in Ireland, that is looking for a Senior Upstream Scientist to join its biologics development team. This role would suit someone who enjoys: Working across diverse biologic modalities, including monoclonal antibodies, recombinant proteins, viral vectors, vaccines, cell-based platforms, and other complex biologics; Hands-on upstream process development, including cell culture, bioreactor work, fed-batch and/or perfusion processes; Supporting projects from early feasibility and process design through optimisation, scale-up, and technical transfer; Running and supporting studies around media/feed optimisation, process parameter evaluation, troubleshooting, and experimental design; Interpreting upstream process data and analytical outputs to identify trends, risks, and improvement opportunities; Building robust upstream strategies that can support later-stage development and manufacturing. A big part of the role is being comfortable not just with the science, but also with working with clients and project management: Lead or contribute to technical discussions with external partners; Present data clearly and confidently; Translate complex scientific findings into practical project decisions; Manage project workstreams, timelines, and deliverables; Coordinate input across upstream, downstream, analytical, quality, and manufacturing teams. They’re looking for someone who combines strong upstream technical depth with the communication skills, ownership, and project management mindset needed in a client-facing CDMO environment.

Job Responsibility

  • Working across diverse biologic modalities
  • hands-on upstream process development
  • supporting projects from feasibility through technical transfer
  • running studies on media/feed optimization, process parameter evaluation, troubleshooting, and experimental design
  • interpreting upstream process data
  • building robust upstream strategies
  • leading or contributing to technical discussions with external partners
  • presenting data
  • translating scientific findings into project decisions
  • managing project workstreams, timelines, and deliverables
  • coordinating input across upstream, downstream, analytical, quality, and manufacturing teams

Requirements

  • Strong upstream technical depth
  • communication skills
  • ownership
  • project management mindset
  • experience with monoclonal antibodies
  • recombinant proteins
  • viral vectors
  • vaccines
  • cell-based platforms
  • other complex biologics
  • hands-on upstream process development including cell culture
  • bioreactor work
  • fed-batch and/or perfusion processes
  • supporting projects from feasibility through technical transfer
  • running studies on media/feed optimization
  • process parameter evaluation
  • troubleshooting
  • experimental design
  • interpreting upstream data
  • leading technical discussions with external partners
  • presenting data
  • managing project workstreams
  • timelines
  • deliverables
  • coordinating across teams

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