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10x Genomics Logo 10x Genomics · Research and Development

Senior Scientist, Reagents Sustaining and Applications

United States, Pleasanton 158400.00 - 214400.00 USD / Year · Job Posted March 04, 2026
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Job Description

We are seeking a Senior Scientist to join the Reagent Sustaining and Applications group to lead sustaining efforts for our Chromium Single Cell products. The role interfaces with R&D, Production, Marketing, and Support to provide the best products to our customers from pre-launch to end of life.

Job Responsibility

  • Lead efforts in testing new materials, tools, and workflows to improve 10x’s state-of-the-art products
  • Collaborate with key internal and external partners to troubleshoot and mitigate any issues that may arise in 10x’s Chromium product line
  • Design and execute experiments to assess the impact of protocol, reagent, or process changes on 10x’s Assays
  • Design, test, and implement process improvements in 10x’s Chromium product line
  • Perform statistical analyses on key assay and QC metrics
  • Update manufacturing documents and present results

Requirements

  • BS, MS or PhD in molecular biology, biochemistry, genetics, microbiology, analytical chemistry, or related fields
  • 12+ years (BS), 10+ years (MS) or 5+ years (PhD) of relevant experience in reagent or assay development and optimization, preferably in the Biotechnology industry
  • Experience analyzing large-scale single-cell or spatial transcriptomics datasets to derive biologically meaningful insights and/or diagnostic biomarkers
  • Ability to design and execute experiments to measure the impact of process improvements and/or formulation changes
  • Experience with a broad variety of molecular biology and analytical techniques including qPCR, nucleic acid isolation, use of plate readers, Bioanalyzers, gel imagers, real-time PCR instruments, etc.
  • Experience with single cell assays including cell handling, library preparation and downstream analysis
  • Experience investigating, identifying, documenting, communicating, and resolving quality control issues in a controlled manufacturing environment
  • Experience defining, documenting, communicating, and transferring new manufacturing workflows into controlled manufacturing environments
  • Meticulous attention to detail and a conscientious work ethic

Nice to have

  • Hands-on experience with the 10x Chromium platform
  • Experience using statistical tools, such as JMP or R to analyze complex data sets, create DOE experiments, and create data trending reports
  • Experience with bioinformatic analysis of Next Generation Sequencing data from Illumina platforms
  • Previous experience supervising and/or mentoring junior staff or leading a multifunctional project team
  • Ability to prioritize competing projects based on impact and alignment with company goals

What we offer

  • Equity grants
  • Comprehensive health and retirement benefit programs
  • Annual bonus program or sales incentive program
  • Competitive and comprehensive health benefits package
  • Easy-to-use benefits that promote wellbeing
  • Family friendly policies like parental leave
  • Generous Time Off
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