CrawlJobs Logo

Senior Scientist, Diagnostic Assay Development

United States, Pleasanton 158400.00 - 214400.00 USD / Year · Job Posted March 13, 2026
Apply Position
Job Link Share

Job Description

10x Genomics is establishing a diagnostics effort to translate our leading single-cell and spatial genomics technologies into impactful clinical applications. We are seeking a highly skilled and motivated Senior Scientist to join the Diagnostic Assay Development team. This is a hands-on bench scientist role with scientific ownership of assay development and optimization, combined with mentorship and technical leadership of junior staff. The Senior Scientist will directly execute, troubleshoot, and refine 10x Genomics–based assays to support development of robust Laboratory Developed Tests (LDTs).

Job Responsibility

  • Assay Development & Execution: Independently execute complex single-cell and spatial genomics workflows
  • Serve as a hands-on technical expert for 10x Genomics platforms
  • Systematically troubleshoot and optimize assay workflows
  • Adapt, refine, and extend published protocols
  • Design and execute feasibility studies
  • Process diverse and challenging clinical sample types
  • Analytical Validation & Documentation: Design and execute experiments supporting analytical validation
  • Generate, review, and maintain high-quality laboratory documentation
  • Analyze assay performance metrics and quality control data
  • Clearly present experimental data and scientific conclusions
  • Scientific Leadership & Mentorship: Provide day-to-day technical guidance and mentorship to junior staff
  • Review experimental plans, data, and lab records
  • Support onboarding and training of new team members
  • Lead by example through hands-on bench work
  • Cross-Functional Collaboration: Collaborate closely with R&D Scientists, Automation Engineers, Bioinformatics, and CLIA Operations teams
  • Lead transfer of optimized assay workflows into the CLIA laboratory
  • Work with lab operations to maintain a high-quality laboratory environment

Requirements

  • Ph.D. in Molecular Biology, Genetics, Biochemistry, or a related field, or M.S. with equivalent industry experience
  • 3+ years (Ph.D.), 5+ years (M.S.) of hands-on industry experience in molecular diagnostics or genomics assay development
  • Extensive, direct hands-on experience with 10x Genomics single-cell and/or spatial technologies, including troubleshooting and optimization
  • Demonstrated ability to independently adapt and refine published molecular biology protocols
  • Strong background in NGS workflows, including nucleic acid extraction, PCR/qPCR, and library preparation
  • Experience working with complex or low-input clinical samples (e.g., FFPE tissue, primary tumor material)
  • Experience with cell culture methods

Nice to have

  • Prior mentoring or supervisory experience preferred
  • Experience working in CLIA, CAP, or ISO 13485–regulated environments strongly preferred
  • Experience with automation or high-throughput workflows is a plus

What we offer

  • Equity grants
  • Comprehensive health and retirement benefit programs
  • Annual bonus program or sales incentive program
  • Generous time off
  • Competitive and comprehensive health benefits package
  • Family friendly policies like parental leave

Looking for more opportunities?

Search for other job offers that match your skills and interests.

Similar Jobs for

Senior Scientist, Diagnostic Assay Development

8 matching positions

New

Senior Research Associate- Diagnostic Assay Development

10x Genomics is establishing a diagnostics effort, translating our leading singl...
Location
Location
United States , Pleasanton
Salary
Salary:
97700.00 - 132100.00 USD / Year
10xgenomics.com Logo
10x Genomics
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • B.S. or M.S. in Molecular Biology, Genetics, Biochemistry, or a related scientific field
  • B.S. with 5+ years or M.S. with 3+ years of hands-on experience in molecular diagnostics or genomics assay development in an industry setting
  • Direct, demonstrable experience with advanced molecular technologies, particularly Next-Generation Sequencing (NGS) workflows
  • Exceptional proficiency in molecular biology techniques, including nucleic acid extraction, PCR/qPCR, and NGS library preparation
  • A proven track-record of using and optimizing and troubleshooting molecular biology protocols
  • Experience working with challenging clinical sample types (e.g., FFPE tissue, primary tumor cells, low-input samples)
  • Experience working within a quality system or environment governed by CLIA, CAP, or ISO 13485 standards strongly preferred
  • Prior hands-on experience with 10x Genomics single-cell or spatial technologies (e.g., Chromium or Xenium platforms) is a strong advantage
  • Experience with automated liquid handling for high-throughput assay execution is a strong advantage
  • experience with microscopy techniques a plus
Job Responsibility
Job Responsibility
  • Hands-on execution of complex single-cell and spatial genomics assays (e.g., sample processing, library preparation, sequencing)
  • Systematically troubleshoot, optimize, and refine specific steps within the assay workflow to improve performance, robustness, and efficiency
  • Perform feasibility studies on new reagents, instrumentation, and process improvements for clinical readiness
  • Prepare and process samples in support of large-scale clinical research studies
  • Generate and maintain meticulous laboratory records, protocols (SOPs), and batch records following Good Documentation Practices (GDP)
  • Execute formal experiments for analytical validation studies, including assessment of accuracy, precision, limit of detection, and reproducibility
  • Ensure all work is conducted under appropriate quality controls
  • Present experimental data clearly and concisely in team meetings and written reports
  • Support the transfer of robust assay workflows to the CLIA operations team
  • Collaborate closely with R&D Scientists, Automation Engineers, and Bioinformatics teams to meet project milestones
What we offer
What we offer
  • Equity grants
  • Comprehensive health and retirement benefit programs
  • Annual bonus program or sales incentive program
  • Health Package
  • Easy-to-use Benefits
  • Family oriented
  • Generous Time Off
  • Fulltime
Read More
Arrow Right

Senior Scientist, Reagents Sustaining and Applications

We are seeking a Senior Scientist to join the Reagent Sustaining and Application...
Location
Location
United States , Pleasanton
Salary
Salary:
158400.00 - 214400.00 USD / Year
10xgenomics.com Logo
10x Genomics
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • BS, MS or PhD in molecular biology, biochemistry, genetics, microbiology, analytical chemistry, or related fields
  • 12+ years (BS), 10+ years (MS) or 5+ years (PhD) of relevant experience in reagent or assay development and optimization, preferably in the Biotechnology industry
  • Experience analyzing large-scale single-cell or spatial transcriptomics datasets to derive biologically meaningful insights and/or diagnostic biomarkers
  • Ability to design and execute experiments to measure the impact of process improvements and/or formulation changes
  • Experience with a broad variety of molecular biology and analytical techniques including qPCR, nucleic acid isolation, use of plate readers, Bioanalyzers, gel imagers, real-time PCR instruments, etc.
  • Experience with single cell assays including cell handling, library preparation and downstream analysis
  • Experience investigating, identifying, documenting, communicating, and resolving quality control issues in a controlled manufacturing environment
  • Experience defining, documenting, communicating, and transferring new manufacturing workflows into controlled manufacturing environments
  • Meticulous attention to detail and a conscientious work ethic
Job Responsibility
Job Responsibility
  • Lead efforts in testing new materials, tools, and workflows to improve 10x’s state-of-the-art products
  • Collaborate with key internal and external partners to troubleshoot and mitigate any issues that may arise in 10x’s Chromium product line
  • Design and execute experiments to assess the impact of protocol, reagent, or process changes on 10x’s Assays
  • Design, test, and implement process improvements in 10x’s Chromium product line
  • Perform statistical analyses on key assay and QC metrics
  • Update manufacturing documents and present results
What we offer
What we offer
  • Equity grants
  • Comprehensive health and retirement benefit programs
  • Annual bonus program or sales incentive program
  • Competitive and comprehensive health benefits package
  • Easy-to-use benefits that promote wellbeing
  • Family friendly policies like parental leave
  • Generous Time Off
  • Fulltime
Read More
Arrow Right

Senior Application Scientist, Test Implementation and Support

The Sr. Technical Services Application Scientist is responsible for providing ou...
Location
Location
United States , Phoenix
Salary
Salary:
67000.00 - 119000.00 USD / Year
exactsciences.com Logo
Exact Sciences
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Ph.D. in a life sciences field
  • Master’s degree in a life sciences field and 2 years of life sciences industry experience in lieu of Ph.D.
  • or Bachelor’s Degree in life sciences or related field and 4 years of life sciences industry experience in lieu of Ph.D.
  • 3+ years of experience in the life sciences industry or a related field
  • 3+ years of experience analyzing data with tools such as Microsoft Office Excel or JMP
  • 2+ years of experience working in a molecular diagnostics/clinical laboratory
  • Professional working knowledge or coursework with molecular biology techniques and Real-Time-PCR Assays
  • Strong understanding of statistical and mathematical methods in biology/genetics
  • Proficient in Microsoft Office, especially Excel
  • Authorization to work in the United States without sponsorship
Job Responsibility
Job Responsibility
  • Receive and document incoming customer communications
  • Work cooperatively with the Technical Services team and internal functional departments to troubleshoot and resolve customer questions or requests
  • Lead troubleshooting of customer issues through root cause investigation, experiment design, study execution, data analysis, and reporting
  • Conduct bench level experiments within several product areas
  • Prepare technical experiment report with all technical specification and information and present to supervisor or project team
  • Coordinate with the Development and Marketing teams for proper implementation of new products
  • Clearly and accurately summarize and document troubleshooting activities or technical summary
  • Prepare detailed technical protocols
  • Communicate customer feedback regarding their product requirements to the developmental team
  • Assist with metrics tracking to monitor performance of the technical services team and quality of the product
What we offer
What we offer
  • Paid time off (including days for vacation, holidays, volunteering, and personal time)
  • Paid leave for parents and caregivers
  • A retirement savings plan
  • Wellness support
  • Health benefits including medical, prescription drug, dental, and vision coverage
  • Bonus eligibility
  • Fulltime
Read More
Arrow Right

Senior Laboratory Manager

Talentmark are recruiting for a Senior Laboratory Manager to join a Life Science...
Location
Location
United Kingdom , Macclesfield
Salary
Salary:
70000.00 - 73000.00 GBP / Year
ckgroup.co.uk Logo
CK Group
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Educated to PhD level ideally
  • Extensive experience in a high-throughput clinical DNA Sequencing laboratory
  • Experience with clinical assay development, process development and project management
  • Proven track record in team leadership, staff development and laboratory management
  • Strong background in Quality Assurance and Quality Control applications in clinical diagnostics
  • Detail-oriented, highly organized, with excellent verbal and written communication skills
  • Ability to troubleshoot technical applications and manage laboratory automation systems
  • Strong knowledge of quality control practices and regulations of UKAS, ISO 15189, CAP and other regulatory agencies
Job Responsibility
Job Responsibility
  • Oversee testing of clinical samples and supervise, mentor, and develop laboratory staff, including scientists, technicians and support personnel
  • Lead a high-throughput clinical genome sequencing laboratory, including technical troubleshooting, developing and writing operational procedures, setting laboratory key performance indicators and establishing quality metrics
  • Design and implement processes and procedures to ensure efficient turnaround times and accuracy of results and oversee daily laboratory operations, including workflow optimization, resource allocation and equipment maintenance
  • Prepare and manage laboratory budgets, monitor expenditures and optimize resource utilization
  • Ensure all processes comply with national regulations, organizational policies and accreditation requirements and maintain ISO 15189, CAP and other accreditation standards, including preparation for audits and inspections
  • Lead initiatives for process improvement and communicate effectively with internal and external stakeholders
  • Fulltime
Read More
Arrow Right

Senior Laboratory Manager

CK Group are recruiting for a Senior Laboratory Manager to join a Life Sciences ...
Location
Location
United Kingdom , Macclesfield
Salary
Salary:
70000.00 - 73000.00 GBP / Year
ckgroup.co.uk Logo
CK Group
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Educated to PhD level ideally
  • Extensive experience in a high-throughput clinical DNA Sequencing laboratory
  • Experience with clinical assay development, process development and project management
  • Proven track record in team leadership, staff development and laboratory management
  • Strong background in Quality Assurance and Quality Control applications in clinical diagnostics
  • Detail-oriented, highly organized, with excellent verbal and written communication skills
  • Ability to troubleshoot technical applications and manage laboratory automation systems
  • Strong knowledge of quality control practices and regulations of UKAS, ISO 15189, CAP and other regulatory agencies
Job Responsibility
Job Responsibility
  • Oversee testing of clinical samples and supervise, mentor, and develop laboratory staff, including scientists, technicians and support personnel
  • Lead a high-throughput clinical genome sequencing laboratory, including technical troubleshooting, developing and writing operational procedures, setting laboratory key performance indicators and establishing quality metrics
  • Design and implement processes and procedures to ensure efficient turnaround times and accuracy of results and oversee daily laboratory operations, including workflow optimization, resource allocation and equipment maintenance
  • Prepare and manage laboratory budgets, monitor expenditures and optimize resource utilization
  • Ensure all processes comply with national regulations, organizational policies and accreditation requirements and maintain ISO 15189, CAP and other accreditation standards, including preparation for audits and inspections
  • Lead initiatives for process improvement and communicate effectively with internal and external stakeholders
  • Fulltime
Read More
Arrow Right
New

Assistant Front Office Manager

Assists the Front Office Manager in administering front office functions and sup...
Location
Location
Malaysia , Kuala Lumpur
Salary
Salary:
Not provided
https://www.marriott.com Logo
Marriott Bonvoy
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • High school diploma or GED
  • 2 years experience in the guest services, front desk, or related professional area
  • OR 2-year degree from an accredited university in Hotel and Restaurant Management, Hospitality, Business Administration, or related major
  • no work experience required
Job Responsibility
Job Responsibility
  • Assists the Front Office Manager in administering front office functions and supervising staff on a daily basis
  • Utilizes interpersonal and communication skills to lead, influence, and encourage others
  • Supervises and manages employees
  • Manages day-to-day operations
  • Handles complaints, settling disputes, and resolving grievances and conflicts
  • Provides services that are above and beyond for customer satisfaction and retention
  • Implements the customer recognition/service program
  • Ensures compliance with all Front Office policies, standards and procedures
  • Functions in place of the Front Office Manager in his/her absence
  • Fulltime
Read More
Arrow Right
New

Pharmacy Technician

At CVS Health, we are focused on transforming health care for our customers and ...
Location
Location
United States , Springfield
Salary
Salary:
16.00 - 24.00 USD / Hour
https://www.cvshealth.com/ Logo
CVS Health
Expiration Date
August 24, 2026
Flip Icon
Requirements
Requirements
  • Must comply with any state board of pharmacy requirements or laws governing the practice of pharmacy, which includes but is not limited to, age, education, and licensure/certification
  • If the state board of pharmacy does not address or mandate a minimum age requirement, must be at least 16 years of age
  • If the state board of pharmacy does not address or mandate a minimum educational requirement, must have a high school diploma or equivalent, or be actively enrolled in high school or high school equivalency program
  • Regular and predictable attendance, including nights and weekends
  • Ability to complete required training within designated timeframe
  • Attention and Focus: Ability to concentrate on a task over a period of time
  • Ability to pivot quickly from one task to another to meet patient and business needs
  • Ability to confirm prescription information and label accuracy, ensuring patient safety
  • Customer Service and Team Orientation: Actively look for ways to help people, and do so in a friendly manner
  • Notice and understand patients' reactions, and respond appropriately
Job Responsibility
Job Responsibility
  • Living our purpose by following all company SOPs at each workstation to help our Pharmacists manage and improve patient health
  • Following pharmacy workflow procedures at each pharmacy workstation (i.e., production, pick-up, drive-thru, and drop-off) for safe and accurate prescription fulfillment
  • Contributing to positive patient experiences by showing empathy and genuine care: creating heartfelt and personalized moments while serving patients at pick-up, drive-thru, and over the phone
  • keeping patients healthy by offering immunizations and other services at the register and over the phone
  • and demonstrating compassionate care by solving or escalating patient problems
  • Completing basic inventory activities, as permitted by law, and as directed by the pharmacy leadership team, such as accurately putting away medication deliveries and completing cycle counts, returns-to-stocks, waiting bin inventories, etc.
  • Contributing to a high-performing team, embracing a growth mindset, and being receptive to feedback
  • actively seeking opportunities to expand clinical and technical knowledge needed to better assist patients
  • Remaining flexible for both scheduling and business needs, while contributing to a safe, inclusive, and engaging team dynamic
  • voluntarily traveling to stores in the market to work shifts as needed by the business
What we offer
What we offer
  • Dental
  • Vision
  • Wellness resources
  • Employee discounts
  • Access to certain voluntary benefits
  • Parttime
Read More
Arrow Right
New

Communications Manager

We are looking for a Communications Manager to lead the communication strategy a...
Location
Location
France , Paris
Salary
Salary:
Not provided
malherbe.paris Logo
MALHERBE Paris
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Proven experience in a similar 360° communication role, ideally within a creative agency, luxury brand, or design studio.
  • Strong relationship management skills, with experience piloting external PR agencies.
  • Flawless written and verbal communication skills in both French and English (daily international context).
  • Highly skilled in Adobe Creative Suite (Photoshop, InDesign, Premiere Pro…).
  • A sharp creative eye and a passion for art, retail, and design.
  • Strong knowledge of CMS tools and CRM/digital marketing platforms (WordPress, Mailchimp, Mailjet).
Job Responsibility
Job Responsibility
  • PR Agency Management: Act as the main, daily point of contact for our PR agency, Pascale Venot. Define priorities, coordinate press launches, monitor clippings, and maximize media coverage for the group.
  • External Communication: Build and execute a strong global external communication strategy to promote our expertise, international projects, and executive leadership.
  • Internal Communication: Foster connection and alignment across our Paris, Shanghai, and New York offices. Design and distribute internal updates to share agency news, wins, and creative inspirations.
  • Newsletters: Own the entire newsletter strategy (internal and external). Curate content, write copy, design templates, and handle the distribution/analytics to engage our clients, partners, and teams.
  • Post-Production & Copywriting: Oversee the creation of high-end communication materials (case studies, social media assets, and press releases). Ensure everything aligns with our premium brand voice.
  • Brand Compliance: Ensure strict adherence to the group’s graphic and brand guidelines across all markets.
  • Performance Tracking: Monitor KPIs for PR campaigns, digital communication, and newsletter engagement, providing regular reports to board members.
  • Fulltime
Read More
Arrow Right