CrawlJobs Logo

Senior Scientist – Research Computational Biology

Amgen

Location Icon

Location:
United States

Category Icon
Category:
Research and Development

Job Type Icon

Contract Type:
Not provided

Salary Icon

Salary:

143320.00 - 174539.00 USD / Year

Job Description:

Join Amgen’s Mission of Serving Patients. The ARIA Computational Biology team is seeking a talented and creative computational biologist to further our mission of serving patients by advancing and replenishing the Amgen therapeutic pipeline. In this role you will apply your expertise in data science and disease biology to accelerate the identification, prioritization, and validation of transformative therapeutic targets in a dynamic cross-functional research environment.

Job Responsibility:

  • Extracting biological insight from complex multi-modal omics and screening data to characterize disease endotypes and mechanisms, identify novel targets and biomarkers, and test therapeutic hypotheses
  • Developing and leveraging methods/platforms to discover, prioritize, and validate targets across diverse diseases and therapeutic modalities
  • Innovative research in close partnership with Amgen therapeutic area scientists, spanning both internal pipeline programs and external partnerships
  • Partnering with our data science and information systems teams to incorporate tools and analyses developed within ARIA Computational Biology into integrated R&D platforms

Requirements:

  • Doctorate in computational biology, bioinformatics, data science, or a related discipline [and relevant post-doc where applicable]
  • Master’s degree and 3 years of relevant research experience
  • Bachelor’s degree and 5 years of relevant research experience
  • Strong programming skills (Python, R, Linux/Unix), familiarity with cloud computing environments, HPC, and collaborative coding practices (e.g., Git)
  • Track record of designing and implementing creative and holistic computational strategies to address challenging research questions
  • Demonstrated expertise in the analysis and interpretation of single cell omics data
  • Excellent presentation and communication skills to convey complex findings to diverse audiences
  • Self-starter with a collaborative mentality and a drive for continuous growth

Nice to have:

  • Strong background in cardiometabolic disease and/or immunology, including application to the interpretation of single-cell data
  • Experience leveraging and fine-tuning transcriptional foundation models, LLMs, and biomedical knowledge graphs to further research goals
  • Familiarity with public data resources (e.g. DepMap, Human Cell Atlas, TCGA, GTEx, and Tahoe-100M) frequently used to augment analyses of internally generated data
  • Experience developing and deploying tools and pipelines to endpoints such as interactive portals (e.g. RShiny apps), workflow management systems (e.g Nextflow), and agentic frameworks
What we offer:
  • A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans
  • Flexible work models, including remote and hybrid work arrangements, where possible

Additional Information:

Job Posted:
December 18, 2025

Employment Type:
Fulltime
Work Type:
Remote work
Job Link Share:

Looking for more opportunities? Search for other job offers that match your skills and interests.

Briefcase Icon

Similar Jobs for Senior Scientist – Research Computational Biology

Scientist, Biological Sciences

An exciting opportunity is available to join Altos Labs. We are seeking highly m...
Location
Location
United States , San Diego
Salary
Salary:
116450.00 - 247000.00 USD / Year
altoslabs.com Logo
Altos Labs
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • PhD and a documented record of professional achievement in the form of impactful publications
  • Excellent computer skills, including advanced proficiency with Google apps, Excel, and Powerpoint graphic skills to produce documents and manage office projects
  • Excellent professional writing skills and the ability to attune through writing and presentations to a variety of audiences including senior executives through entry-level employees
  • Problem-solving skills sufficient to identify issues, conduct research, and develop innovative solutions
  • Ability to maintain cooperative working relationships with a broad range of people, including staff colleagues, lab members, faculty, outside agencies and collaborators, and the community
  • Demonstrated high productivity and ability to complete work in a timely manner
  • Ability to organize work and set priorities
  • Ability to focus on details to produce accurate, quality work driven by deadlines
  • Ability to work in a dynamic environment and with others in a team
  • Strengths in dealing with ambiguity
Job Responsibility
Job Responsibility
  • Engage in ground-breaking and innovative science
  • Support and manage internal/external collaborations in one or more multidisciplinary projects to accelerate essential research activities
  • Study the mechanistic basis of cell programming for health and rejuvenation
  • Responsible for mentoring graduate students
  • Responsible for developing project-specific experimental strategies, techniques, and procedures
  • Responsible for helping PI train lab members, including scientists and technicians
  • Contribute to writing and dissemination of research results
  • Carry out research projects in collaboration with the PI
Read More
Arrow Right
New

Senior Bioinformatics Scientist

Job Advert: Senior Bioinformatics Scientist. Our client is an emerging leader wi...
Location
Location
United States , San Francisco
Salary
Salary:
170000.00 - 190000.00 USD / Year
signifytechnology.com Logo
Signify Technology
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • PhD in Biological Sciences, Bioinformatics, Computational Biology, or related field, with 3+ years of experience developing production-level bioinformatics pipelines
  • Deep expertise in analyzing bulk/single-cell RNAseq data and performing differential gene expression using state-of-the-art tools
  • Significant experience building production-level Snakemake (or Nextflow) pipelines, with local and cloud-based deployments
  • Strong knowledge of sequence analysis (alignment, assembly) and molecular biology, with experience in Oxford Nanopore and Illumina sequencing
  • Proficiency in Python (numpy, pandas, Jupyter, Biopython) and package management (e.g., Conda)
  • Hands-on experience with Docker, Apptainer, or Singularity for containerized workflows
  • Expertise in Git/GitHub and Linux shell scripting for version control and automation
  • Proficiency in developing intuitive web tools for bioinformatics reporting (e.g., R Shiny, Streamlit)
  • Familiarity with public genomic data repositories (e.g., NCBI, Ensembl) and large-scale genomic data processing
  • Strong communication skills and ability to write clean, maintainable, production-ready code
Job Responsibility
Job Responsibility
  • Designing and optimizing high-performance bioinformatics pipelines for processing thousands of daily samples, leveraging tools like Snakemake and cloud deployments
  • Innovating sequence analysis workflows for bulk/single-cell RNAseq, differential gene expression, and large-scale genomics, ensuring robust and scalable solutions
  • Troubleshooting complex sequencing data challenges, from biological artifacts to platform-specific issues, to ensure reliable outputs
  • Developing intuitive web tools (e.g., Streamlit, R Shiny) and data visualizations to transform raw bioinformatics data into actionable insights
  • Providing thought leadership and mentoring junior team members, fostering a culture of innovation and collaboration
  • Staying ahead of industry trends, integrating emerging bioinformatics tools to enhance our offerings for biopharma and research clients
What we offer
What we offer
  • Competitive Compensation: Highly competitive remuneration
  • Generous Time Off: 4 weeks paid time off + 10 paid holidays
  • Comprehensive Health Coverage: Health, dental, and vision insurance, plus life insurance and mental health coverage
  • Retirement and Wellness: 401(k) with matching, Health Advocate services, and gym membership
  • Impactful Work: Contribute directly to accelerating biotech research, supporting novel therapies and sustainability
  • Innovative Environment: Work with cutting-edge tools (e.g., Snakemake, Streamlit, AWS) and collaborate with top-tier researchers
  • Supportive Culture: Join a passionate, inclusive team that values creativity, mentorship, and professional growth
  • Fulltime
Read More
Arrow Right

Senior / Principal Machine Learning Scientist

Our mission is to restore cell health and resilience through cell rejuvenation t...
Location
Location
United Kingdom , Cambridge
Salary
Salary:
136000.00 - 261050.00 GBP / Year
altoslabs.com Logo
Altos Labs
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Ph.D. in Machine Learning, Computer Science, Artificial Intelligence, Statistics, or a related quantitative field
  • 6+ years of relevant post-PhD work experience in either an academic or industry setting
  • Proven experience developing and applying complex machine learning models
  • A strong track record of leading and publishing innovative, peer-reviewed research in top-tier ML conferences or high-impact scientific journals
  • Excellent scientific communication skills
  • Expertise in several of the following: deep learning, reinforcement learning, generative models, language models, computer vision, Bayesian inference, causal reasoning & inference, transfer & multi-task learning, graph neural networks, active learning, hybrid mechanistic/ML models
  • Proven experience applying sophisticated ML techniques to molecular and cell biological data sets
Job Responsibility
Job Responsibility
  • Pioneer novel machine learning methodologies and statistical frameworks
  • Contribute to setting the long-term technical vision and research strategy for a core domain within the Institute of Computation
  • Translate your deep understanding of the mathematical and theoretical underpinnings of cutting-edge AI research into high-impact applications
  • Design, implement, and optimize large-scale machine learning systems using modern frameworks and agile practices
  • Develop and manage efficient distributed training strategies across multiple GPUs and compute clusters
  • Develop robust approaches for multi-modal data integration and cross-domain mapping to extract actionable biological insights
  • Apply computational thinking to solve problems in drug target identification, compound assessment, and prediction of cellular perturbation responses
  • Lead the full ML development lifecycle from theoretical conception and data strategy through model development, training, and evaluation
  • Act as a key technical mentor to Machine Learning Scientists and Engineers
  • Fulltime
Read More
Arrow Right

Senior / Principal Machine Learning Scientist

Our mission is to restore cell health and resilience through cell rejuvenation t...
Location
Location
United States , Redwood City; San Diego
Salary
Salary:
260950.00 - 509450.00 USD / Year
altoslabs.com Logo
Altos Labs
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Ph.D. in Machine Learning, Computer Science, Artificial Intelligence, Statistics, or a related quantitative field
  • 6+ years of relevant post-PhD work experience in either an academic or industry setting
  • Proven experience developing and applying complex machine learning models
  • A strong track record of leading and publishing innovative, peer-reviewed research in top-tier ML conferences or high-impact scientific journals
  • Excellent scientific communication skills
  • Expertise in several of the following: deep learning, reinforcement learning, generative models, language models, computer vision, Bayesian inference, causal reasoning & inference, transfer & multi-task learning, graph neural networks, active learning, hybrid mechanistic/ML models
  • Proven experience applying sophisticated ML techniques to molecular and cell biological data sets
Job Responsibility
Job Responsibility
  • Pioneer novel machine learning methodologies and statistical frameworks
  • Contribute to setting the long-term technical vision and research strategy for a core domain
  • Translate your deep understanding of the mathematical and theoretical underpinnings of cutting-edge AI research into high-impact applications
  • Design, implement, and optimize large-scale machine learning systems
  • Develop and manage efficient distributed training strategies across multiple GPUs and compute clusters
  • Develop robust approaches for multi-modal data integration and cross-domain mapping
  • Apply computational thinking to solve problems in drug target identification, compound assessment, and prediction of cellular perturbation responses
  • Lead the full ML development lifecycle
  • Act as a key technical mentor to Machine Learning Scientists and Engineers
Read More
Arrow Right
New

Social Worker

The primary function of the MSW is to provide coordinated care in the home to cl...
Location
Location
United States , Clermont
Salary
Salary:
Not provided
angelscarehealth.com Logo
Angels Care Home Health
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Master’s degree in social work
  • State Certification
  • current State Driver’s License
  • One year of experience as an MSW in a health care agency
  • Working knowledge of community resources
  • Proof of current CPR and Hepatitis profile
Job Responsibility
Job Responsibility
  • Provide coordinated care in the home to clients of all age groups
  • Perform psychosocial assessments, analysis, counseling, and referrals to meet the needs of the patient/family
  • Assess home health patient to identify psychosocial, financial, environmental, and community needs
  • Use effective interpersonal relations and communication skills
  • Meet mandatory continuing education requirements
  • Maintain a working knowledge of public and private eligibility standards
  • Promote Agency philosophy and administrative policies to ensure quality of care
What we offer
What we offer
  • Generous Paid Time Off
  • Extensive Training
  • Full Health, Dental, & Vision Benefits (Available 1st Month)
  • Company-Matched 401(k)
  • Career Advancement
  • Parttime
Read More
Arrow Right
New

Occupational Therapist

Occupational Therapist (OT) for Angels Care Home Health. We administer medical s...
Location
Location
United States , Clermont
Salary
Salary:
Not provided
angelscarehealth.com Logo
Angels Care Home Health
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Current state license as an Occupational Therapist
  • Two years of experience as an Occupational Therapist
  • Current CPR and Hepatitis profile
  • Knowledge of durable medical equipment
Job Responsibility
Job Responsibility
  • Perform clinical assessment
  • Identify patient needs and appropriateness of patient
  • Document, prepare, and complete a Plan of Care, progress notes, and other clinical record documentation on an ongoing basis
  • Revise the POC based on evaluation and ongoing assessment
  • Applies concepts of infection control and universal precautions in coordinating/performing patient care
  • Accepts clinical assignments that are consistent with education and competence to care for patients
  • Uses effective interpersonal relations and communication skills
  • facilitates the use of these skills by other team members to achieve desirable outcomes
  • Assess physical, social, and cultural components of the patient’s occupational environment
What we offer
What we offer
  • Monday through Friday Schedule
  • Salary + Vehicle Allowance + On-Call Pay (Full-Time)
  • Full Health, Dental, & Vision Benefits (Full-Time)
  • Generous Paid Time Off
  • Extensive Training
  • Company-Matched 401(k)
  • Career Advancement
Read More
Arrow Right
New

Registered Nurse

The Registered Nurse (RN) Case Manager coordinates all aspects of the patient’s ...
Location
Location
United States , Fort Myers
Salary
Salary:
Not provided
angelscarehealth.com Logo
Angels Care Home Health
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Graduate of an accredited diploma, Associate or Baccalaureate School of Nursing
  • Current state license as a Registered Nurse
  • Current state Driver’s License
  • One-year experience as a Registered Nurse, two preferred
  • Proof of current CPR and Hepatitis consent/declination
  • Reliable transportation with valid and current auto liability insurance
Job Responsibility
Job Responsibility
  • Coordinates all aspects of the patient’s home care
  • Interact with other medical disciplines as needed & provide professional care to the patient
  • Perform the admission visit to the patient in the home & determine the patient’s eligibility for home care services & develop the plan of care to be followed
What we offer
What we offer
  • Highly Competitive Salary + Vehicle Allowance
  • Generous Paid Time Off
  • Extensive Training
  • Full Health, Dental, & Vision Benefits (Available 1st Month)
  • Company-Matched 401(k)
  • Career Advancement
Read More
Arrow Right
New

Licensed Practical Nurse

Licensed Practical Nurse (LPN) for Angels Care Home Health. Our nurses are not j...
Location
Location
United States , Fort Myers
Salary
Salary:
Not provided
angelscarehealth.com Logo
Angels Care Home Health
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Graduate of an accredited school of practical/vocational nursing
  • Current state license as an LPN
  • Current State’s Driver’s License
  • Two years’ experience as an LPN, home health preferred
  • Proof of current CPR and Hepatitis profile
Job Responsibility
Job Responsibility
  • Administer skilled nursing care, under the supervision of a registered nurse, for clients of all ages in their place of residence
  • Coordinates care with the interdisciplinary team, patient/family, and referring agency
What we offer
What we offer
  • Generous Paid Time Off
  • Extensive Training
  • Full Health, Dental, & Vision Benefits (Available 1st Month)
  • Company-Matched 401(k)
  • Career Advancement
Read More
Arrow Right
Welcome to CrawlJobs.com
Your Global Job Discovery Platform
At CrawlJobs.com, we simplify finding your next career opportunity by bringing job listings directly to you from all corners of the web. Using cutting-edge AI and web-crawling technologies, we gather and curate job offers from various sources across the globe, ensuring you have access to the most up-to-date job listings in one place.