Senior Scientist – Research Computational Biology Platforms Job at Amgen (South San Francisco)

Senior Scientist – Research Computational Biology

Join Amgen’s Mission of Serving Patients. The ARIA Computational Biology team is...

Location

United States

Salary:

143320.00 - 174539.00 USD / Year

Amgen

Expiration Date

Until further notice

Requirements

Doctorate in computational biology, bioinformatics, data science, or a related discipline [and relevant post-doc where applicable]
Master’s degree and 3 years of relevant research experience
Bachelor’s degree and 5 years of relevant research experience
Strong programming skills (Python, R, Linux/Unix), familiarity with cloud computing environments, HPC, and collaborative coding practices (e.g., Git)
Track record of designing and implementing creative and holistic computational strategies to address challenging research questions
Demonstrated expertise in the analysis and interpretation of single cell omics data
Excellent presentation and communication skills to convey complex findings to diverse audiences
Self-starter with a collaborative mentality and a drive for continuous growth

Job Responsibility

Extracting biological insight from complex multi-modal omics and screening data to characterize disease endotypes and mechanisms, identify novel targets and biomarkers, and test therapeutic hypotheses
Developing and leveraging methods/platforms to discover, prioritize, and validate targets across diverse diseases and therapeutic modalities
Innovative research in close partnership with Amgen therapeutic area scientists, spanning both internal pipeline programs and external partnerships
Partnering with our data science and information systems teams to incorporate tools and analyses developed within ARIA Computational Biology into integrated R&D platforms

What we offer

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models, including remote and hybrid work arrangements, where possible

Fulltime

Senior Bioinformatics Scientist

Job Advert: Senior Bioinformatics Scientist. Our client is an emerging leader wi...

Location

United States , San Francisco

Salary:

170000.00 - 190000.00 USD / Year

Signify Technology

Expiration Date

Until further notice

Requirements

PhD in Biological Sciences, Bioinformatics, Computational Biology, or related field, with 3+ years of experience developing production-level bioinformatics pipelines
Deep expertise in analyzing bulk/single-cell RNAseq data and performing differential gene expression using state-of-the-art tools
Significant experience building production-level Snakemake (or Nextflow) pipelines, with local and cloud-based deployments
Strong knowledge of sequence analysis (alignment, assembly) and molecular biology, with experience in Oxford Nanopore and Illumina sequencing
Proficiency in Python (numpy, pandas, Jupyter, Biopython) and package management (e.g., Conda)
Hands-on experience with Docker, Apptainer, or Singularity for containerized workflows
Expertise in Git/GitHub and Linux shell scripting for version control and automation
Proficiency in developing intuitive web tools for bioinformatics reporting (e.g., R Shiny, Streamlit)
Familiarity with public genomic data repositories (e.g., NCBI, Ensembl) and large-scale genomic data processing
Strong communication skills and ability to write clean, maintainable, production-ready code

Job Responsibility

Designing and optimizing high-performance bioinformatics pipelines for processing thousands of daily samples, leveraging tools like Snakemake and cloud deployments
Innovating sequence analysis workflows for bulk/single-cell RNAseq, differential gene expression, and large-scale genomics, ensuring robust and scalable solutions
Troubleshooting complex sequencing data challenges, from biological artifacts to platform-specific issues, to ensure reliable outputs
Developing intuitive web tools (e.g., Streamlit, R Shiny) and data visualizations to transform raw bioinformatics data into actionable insights
Providing thought leadership and mentoring junior team members, fostering a culture of innovation and collaboration
Staying ahead of industry trends, integrating emerging bioinformatics tools to enhance our offerings for biopharma and research clients

What we offer

Competitive Compensation: Highly competitive remuneration
Generous Time Off: 4 weeks paid time off + 10 paid holidays
Comprehensive Health Coverage: Health, dental, and vision insurance, plus life insurance and mental health coverage
Retirement and Wellness: 401(k) with matching, Health Advocate services, and gym membership
Impactful Work: Contribute directly to accelerating biotech research, supporting novel therapies and sustainability
Innovative Environment: Work with cutting-edge tools (e.g., Snakemake, Streamlit, AWS) and collaborate with top-tier researchers
Supportive Culture: Join a passionate, inclusive team that values creativity, mentorship, and professional growth

Fulltime

New

Senior Scientist – Research Computational Biology (ARIA)

Join Amgen’s Mission of Serving Patients. The ARIA Computational Biology team is...

Location

United States , South San Francisco; Boston; Thousand Oaks

Salary:

146404.00 - 198076.00 USD / Year

Amgen

Expiration Date

Until further notice

Requirements

PhD in computational biology, bioinformatics, data science, or a related discipline [and relevant post-doc where applicable]
Master’s degree in computational biology, bioinformatics, data science, or a related discipline and 3 years of relevant research experience
Bachelor’s degree in computational biology, bioinformatics, data science, or a related discipline and 5 years of relevant research experience
Strong background in cardiometabolic disease and/or immunology, including applications in the interpretation of single-cell data
Proficient in extracting actionable mechanistic insights from complex biological datasets through development and creative application of AI/ML-based analytical strategies
Strong programming skills (Python, R, Linux/Unix) and experience with cloud computing environments, HPC, and collaborative coding practices (e.g., Git)
Track record of designing and executing creative and holistic computational strategies to address challenging research questions
Proven expertise in the analysis and interpretation of single-cell omics data
Excellent communication and presentation skills, with the ability to convey complex concepts to diverse audiences
Self-motivated, collaborative, and committed to continuous learning and growth

Job Responsibility

Deriving biological insight from complex multi-modal omics and perturbation screening data to characterize disease endotypes and mechanisms, identify novel targets and biomarkers, and test therapeutic hypotheses
Conducting innovative, collaborative research in close partnership with Amgen therapeutic area scientists and our Discovery Sciences, Advanced Technologies, and AI (DATA) team, spanning discovery platforms, internal pipeline programs, and external partnerships

What we offer

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models where possible

Fulltime

Senior Director – BioIntelligence

The AI & Data for Engineered Biologics (AIDE) organization at Amgen is seeking a...

Location

United States , Thousand Oaks

Salary:

239775.00 - 295217.00 USD / Year

Amgen

Expiration Date

Until further notice

Requirements

Doctorate degree in Computational Biology, Machine Learning, Bioinformatics, Computer Science, Biophysics, or related field and 5 years of experience applying machine learning or computational modeling to biological systems
OR Master’s degree in Computational Biology, Machine Learning, Bioinformatics, Computer Science, Biophysics, or related field and 9 years of experience applying machine learning or computational modeling to biological systems
OR Bachelor’s degree in Computational Biology, Machine Learning, Bioinformatics, Computer Science, Biophysics, or related field and 11 years of experience applying machine learning or computational modeling to biological systems
At least 5 years experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources

Job Responsibility

Lead the BioIntelligence Team within our Large Molecule Discovery organization, defining strategy and priorities for AI-driven biologics modeling
Develop and execute a roadmap for machine learning and AI approaches that accelerate engineered biologics discovery
Align BioIntelligence capabilities with broader Research and Large Molecule Discovery priorities
Oversee development of predictive models for key biologics properties, including developability, stability, manufacturability, and immunogenicity
Advance modeling approaches using modern AI techniques such as: protein language models
generative modeling and inverse folding
representation learning
active learning and Bayesian optimization
Guide the use of multimodal biological datasets including sequence, structure, and experimental assay data
Lead development of production-quality research software and deployable ML models used across discovery teams

What we offer

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models where possible

Fulltime

Director senior director antibody discovery

BigHat is seeking an exceptional and highly experienced individual for a positio...

Location

United States , San Mateo

Salary:

230000.00 - 270000.00 USD / Year

BigHat Biosciences

Expiration Date

Until further notice

Requirements

Ph.D. in molecular biology, biochemistry, protein engineering, or related discipline with 12+ years of experience in antibody discovery and engineering within academia, biotechnology, or pharmaceutical industries
8+ years of managerial experience leading scientific teams
Strong expertise with protein display systems such as yeast, phage, mammalian, or mRNA display
Demonstrated experience with antibody library design, construction, screening, and selection analysis
Deep understanding of antibody structure-function relationships and mechanisms of antigen recognition
Experience integrating antibody discovery workflows with downstream characterization and developability assessment, including functional screening and biophysical evaluation of antibody candidates
Familiarity with computational or ML-enabled approaches to protein design and optimization
Experience advancing biologics from early discovery through lead optimization stages
Knowledge of diverse antibody modalities including multispecific antibodies, antibody fragments, and other advanced formats
Strong leadership skills with experience building and mentoring scientific teams

Job Responsibility

Lead BigHat’s antibody discovery and display functions, setting the scientific, technical, and strategic direction
Oversee the routine execution of display-based selection campaigns to enhance and diversify affinity, developability, and function across diverse antibody formats and antigen types in support of BigHat and BigHat-partnered therapeutic programs
Manage and mentor a team of scientists responsible for antibody library design, generation, screening, selection, and early optimization
Shape and expand BigHat’s antibody discovery technologies and capabilities, including new display and selection methods, library design strategies, and technical approaches that leverage and enhance the company’s integrated experimental and computational platform
Provide scientific leadership across discovery and early optimization efforts, ensuring antibodies emerging from selections possess strong functional and developability characteristics
Work closely with leaders in Protein Sciences, Data Science/Machine Learning, Engineering, and Platform groups to ensure seamless progression from discovery through characterization and optimization
Collaborate with biology and therapeutic research leads to ensure display outputs align with and advance program objectives
Foster a collaborative and high-performance culture within the discovery organization

What we offer

Range of health insurance plan options through Anthem and Kaiser (monthly credit if benefit waived)
Dental, and vision coverage through Guardian
Additional well-being benefits through Nayya, OneMedical, Wagmo, Rula, and more
401(k) with company match
DTO, two weeks of company-wide shutdown, and 12 company holidays
Paid parental leave
bonus
options

Fulltime

Engagement Manager

Proteins are the molecular machines of life, used for many therapeutic, diagnost...

Location

Netherlands; Switzerland , Amsterdam; Zürich

Salary:

Not provided

Cradle

Expiration Date

Until further notice

Requirements

Deep understanding of biopharma R&D workflows and the ability to confidently engage with executive stakeholders as well as experimental and computational scientists
5–7+ years in enterprise client-facing roles (program management, consulting, or customer success) ideally in Life Sciences
Proven ability to lead complex, multi-stakeholder programs and drive measurable ROI
Strong relationship-building, executive presence, crisp communication, and excellent organizational skills
Comfortable presenting scientific and business insights to internal and external cross-functional audiences
MSc or advanced degree in Molecular Biology, Biotechnology, Bioengineering, or a related field, or equivalent professional experience
Willingness to travel to- and work from customer sites (20% of the time)

Job Responsibility

Oversee post-sale success across global biotech and pharma customers, from initial onboarding to long-term, broad adoption
Define and track portfolio-level success metrics and ROI, presenting progress to senior customer stakeholders
Establish and lead steering committees to align stakeholders and ensure Cradle delivers measurable impact
Understand customer budget cycles, licensing models, and R&D roadmaps to identify timely opportunities for growth and renewals
Partner with Account Executives to expand Cradle’s footprint across new business units and therapeutic areas
Coordinate with Scientific Advisors to ensure smooth project initiation, resource allocation, and execution within licensed project slots
Manage multi-workstream engagements, ensuring alignment across Science, Product, and ML teams
Inspire and lead your cross-functional Cradle team to deliver seven star customer experiences
Act as the primary escalation and coordination point for enterprise accounts
Solicit, capture and communicate customer feedback, driving improvements in Cradle’s product and service delivery

What we offer

Very competitive salary
Generous equity stake (for full time employees)
Wide range of benefits
Career progression opportunities

Fulltime

New

Engineer I, EHS

You, as Engineer I, EHS, will support supervisors by providing tools and advice ...

Location

Costa Rica , Cartago

Salary:

Not provided

Baxter

Expiration Date

Until further notice

Requirements

Bachelor’s degree in occupational health and safety, or equivalent experience, or higher education in related areas
Experience in related fields of 1 years minimum
Sophisticated English, bilingual desirable
Certification in ISO 14001:2014, ISO 45001:2018 and ISO 50001 standards (desirable)
Internal Auditor Certificate (desirable)

Job Responsibility

Promote compliance with quality requirements, Good Manufacturing Practices (GMPs) and Good Documentation Practices (GDP)
Promote and participate in ICare's initiatives: if you see something, do something
Respond to and resolve in a timely manner the problems that may affect the quality, safety or efficiency of the product or the regulatory consistency of the process
Continuously seek regulatory completion in your process
Stay aligned with EHS rules and procedures
Ensure the people in your charge follow them
Provide crucial training spaces for EHS issues
Promote the culture of safety, and ensure compliance with all the guidelines that the organization settles vital to align with the applicable legal and/or corporate requirements of its area passionate about protecting safety, its own health and that of its personnel in charge, and the environment
Build, coordinate and implement the company's Ergonomics program
Build, coordinate and implement the company's Environmental program (Management of waste, wastewater, air emissions, drinking water, identification and evaluation of environmental aspects, assessment of relevant regulations, training, among others)

New

Store Operator

GrainCorp Feeds is a national animal feed business, based in Hamilton NZ, dealin...

Location

New Zealand , Waharoa

Salary:

Not provided

GrainCorp

Expiration Date

Until further notice

Requirements

Current forklift licence with F and W endorsement
Experience working in a warehousing / logistics role
Good communication skills
Ability to follow direction
Ability to work collaboratively and autonomously
Capable of lifting up to 20kg in weight
Solid understanding of safety standards

Job Responsibility

Bagging and pallet stacking
Moving / loading palletised stock

What we offer

Ongoing training and safety programs
Paid Parental leave and birthday leave
Employee referral bonus scheme
Standard Southern Cross Health Insurance that covers employee, spouse and kids up to the age of 18
Family Inclusive Workplace accredited employer, committed to supporting you both on and off the job

Fulltime

Senior Scientist – Research Computational Biology Platforms

Amgen

Location:
United States , South San Francisco ▼
Boston
Thousand Oaks

Category:
Research and Development

Contract Type:
Not provided

Salary:

Job Description:

Job Responsibility:

Requirements:

Additional Information:

Job Posted:
April 16, 2026

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