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Senior Scientist – Research Computational Biology (ARIA)

United States, South San Francisco 146404.00 - 198076.00 USD / Year · Job Posted April 16, 2026
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Job Description

Join Amgen’s Mission of Serving Patients. The ARIA Computational Biology team is seeking a talented and creative computational biologist to further our mission of serving patients by advancing and replenishing the Amgen therapeutic pipeline. In this role, you will apply your expertise in data science and mechanistic disease biology to accelerate the identification, prioritization, and validation of transformative therapeutic targets within a dynamic, cross-functional research environment.

Job Responsibility

  • Deriving biological insight from complex multi-modal omics and perturbation screening data to characterize disease endotypes and mechanisms, identify novel targets and biomarkers, and test therapeutic hypotheses
  • Conducting innovative, collaborative research in close partnership with Amgen therapeutic area scientists and our Discovery Sciences, Advanced Technologies, and AI (DATA) team, spanning discovery platforms, internal pipeline programs, and external partnerships

Requirements

  • PhD in computational biology, bioinformatics, data science, or a related discipline [and relevant post-doc where applicable]
  • Master’s degree in computational biology, bioinformatics, data science, or a related discipline and 3 years of relevant research experience
  • Bachelor’s degree in computational biology, bioinformatics, data science, or a related discipline and 5 years of relevant research experience
  • Strong background in cardiometabolic disease and/or immunology, including applications in the interpretation of single-cell data
  • Proficient in extracting actionable mechanistic insights from complex biological datasets through development and creative application of AI/ML-based analytical strategies
  • Strong programming skills (Python, R, Linux/Unix) and experience with cloud computing environments, HPC, and collaborative coding practices (e.g., Git)
  • Track record of designing and executing creative and holistic computational strategies to address challenging research questions
  • Proven expertise in the analysis and interpretation of single-cell omics data
  • Excellent communication and presentation skills, with the ability to convey complex concepts to diverse audiences
  • Self-motivated, collaborative, and committed to continuous learning and growth

What we offer

  • A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans
  • Flexible work models where possible

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