Senior Researcher - Real World Evidence Job at Microsoft Corporation (Redmond)

Senior Director, Global Real-World Evidence & Health Outcomes Research Lead, Specialty Medicines

Robust health outcomes data is necessary to support launch optimization, reimbur...

Location

United States , Philadelphia

Salary:

Not provided

GSK

Expiration Date

Until further notice

Requirements

PhD, PharmD or equivalent level qualification in health outcomes, patient reported outcomes, health economics, epidemiology, pharmacy, health, or life sciences
5+ years working in global pharmaceuticals in a leadership role with line management experience
Strong business acumen and ability to translate customer needs into actionable data generation plan
Methods expertise to guide and lead team in delivering robust payer evidence deliverables and credibility to engage meaningfully with external experts & leaders in the field
Knowledge of the diversity and complexity of healthcare markets, health technology assessment agencies, and reimbursement decision making globally, in region and in local markets
Understanding of how health economics, health outcomes, comparative effectiveness research, PRO research and the use of PRO instruments can be applied at local decision-making levels, including support of clinical practice
Deep knowledge and strong communication skills are critical for interpreting and translating complex concepts and results effectively to a variety of audiences to impact decision making
Deep knowledge of drug development and therapy area
Strong matrix leadership and stakeholder management skills, with the ability to work independently and build credibility across the enterprise
Experience across product lifecycles

Job Responsibility

Provide leadership, management, and development of Data Generation book of work
Partner effectively with matrix stakeholders in planning and design of the DGP for the asset, drive disciplined execution of studies and activities, translate results, and disseminate data and research findings to all relevant internal and external stakeholders
Provide scientific leadership for best practice in real world evidence/ non-interventional study methodologies, including enabling external scientific advice, ensuring appropriate protocol review committee’s advice sought and incorporated
Drive innovation and inform ideas and options through effective engagement with external experts, clinical guideline groups, HTA agencies, methodology and policy forums, and by leveraging knowledge of the external policy and decision maker environment to enable more efficient evidence development for the asset across the lifecycle (e.g. discovery, launching and life cycle management assets)
Integrate excellent understanding of the evolving global health technology assessment bodies, clinical guidelines groups, policy decision makers and payer environment, including recommendation, reimbursement, pricing, and access in relevant therapy area
Lead discussions with key stakeholders on prioritization of data generation in order to meet business and customer needs
Deliver the materials to inform internal governance decision making (e.g. Medical Review Board, etc)
Facilitate alignment and partnership to enable more effective interactions within the complex stakeholder matrix, e.g. clinical, commercial, market access, medical affairs functions, priority market LOCs as well as external third-party suppliers
Represent GSK in external collaborations, engagement and scientific evidence requirements with scientific partners, reimbursement bodies and other decision makers
Drive quality and compliance through team to ensure trust for the evidence that is delivered

What we offer

Competitive base salary
Annual bonus based on company performance
Flexible working options available for most roles
Learning and career development
Access to healthcare & wellbeing programmes
Employee recognition programmes

Fulltime

Associate Director, US Real-World Evidence and Health Outcomes – Oncology Pipeline

This Associate Director role supports the US Pipeline Oncology Director in leadi...

Location

United States , Philadelphia; Durham; Collegeville

Salary:

Not provided

GSK

Expiration Date

Until further notice

Requirements

Master’s degree or PhD in health economics and outcomes research, epidemiology, public health, biostatistics, or a related discipline
At least 1-3 years of experience the pharmaceutical industry and/or managed care, hospital, academic, or healthcare consulting environment with exposure to HEOR/RWE strategy and application
Know-how regarding the US payer/reimbursement and access environment and familiarity with how payer evidence needs inform evidence planning and deliverables (e.g., value evidence strategy, AMCP-style dossier content, budget impact/cost-effectiveness, payer-focused materials), gained through academic, internship, or professional experience
Expertise in RWE and economic evaluation study designs/methods evidenced by publications and/or contributing to study concept sheets and protocols (including clear research questions, endpoints, data source selection, and bias/confounding mitigation), reviewing/authoring key sections of statistical analysis plans and study reports, and ensuring publication/disclosure readiness in accordance with internal SOPs and external requirements
Strong communication and presentation skills, demonstrated by developing and presenting clear, decision-oriented materials (e.g., evidence strategy slides, executive readouts) and summarizing outcomes/next steps for senior audiences
Proven ability to prioritize, pivot, and manage multiple projects simultaneously in a matrix environment

Job Responsibility

Evidence strategy and planning: Co-develop and maintain US RWE & HO plans for 1–2 priority pipeline assets/indications, aligned to US medical, payer, and access needs
translate strategy into actionable workplans, timelines, and resourcing proposals
Study leadership (RWE/HEOR): Own day-to-day leadership for assigned real-world evidence and health outcomes studies (e.g., real-world evidence studies, cost-effectiveness/budget impact analyses, burden of illness, treatment patterns, patient-focused outcomes) including design and execution in partnership with internal functions and external vendors
Cross-functional stakeholder management: Support the US Pipeline Oncology Director in running cross-functional evidence strategy forums and asset-specific meetings by developing agendas/materials, surfacing options, documenting decisions, and tracking actions to closure
Scientific communication and quality: Draft/review project specifications, protocols, statistical analysis plans, study reports, abstracts, posters, and manuscripts
ensure adherence to SOPs and high scientific/operational quality
Trial design input for US relevance: Provide feedback to Clinical Development and cross-functional teams on optimal trial design to ensure enrollment of US-relevant patient populations and collection of endpoints/outcomes that support US stakeholder needs (e.g., health-related quality of life, patient-reported outcomes, resource utilization, and other health outcomes measures)
Internal decision support: Provide RWE & HO input to internal decision-making during development and commercialization planning (e.g., trial design considerations, data gap assessments, value messages, evidence prioritization and sequencing)
Marketed product support : Contribute ~20% effort to US RWE & HO strategy and execution for a marketed product in endometrial and rectal cancer, including data generation planning, cross-functional alignment, and delivery of analyses/publications that support lifecycle evidence needs and value communication
External insight generation: Maintain strong alignment with Field Based Payer Medical Teams and other field stakeholders to obtain customer insights

What we offer

Competitive base salary
Annual bonus based on company performance
Flexible working options available for most roles
Learning and career development
Access to healthcare & wellbeing programmes
Employee recognition programmes

Fulltime

Senior Security Researcher

1Password is growing. We’ve surpassed $400M in ARR and we’re continuing to accel...

Location

United States; Canada

Salary:

153000.00 - 214000.00 USD / Year

1Password

Expiration Date

Until further notice

Requirements

4+ years of progressive experience in security research, offensive security, or vulnerability research
Education: Bachelor’s degree in Computer Science, Computer Engineering, Information Security, or a related field
or equivalent practical experience
Security research experience: Proven track record of discovering and responsibly disclosing original vulnerabilities, ideally with published CVEs, advisories, or equivalent publicly-recognized findings
Offensive security experience: A track record of hands-on experience in vulnerability research, exploit development, or advanced adversarial simulation techniques
Sufficient domain experience in two or more of the following domains: application security, Linux system internals, Windows system internals, macOS system internals, AI/Agentic security, Web application security, or Mobile application security
AI security experience: Familiarity with prompt injection, data poisoning, AI design architecture, AI-based attacks, and related vectors
Software engineering proficiency: Proficiency in one or more programming languages such as Go, Rust, Python, Ruby, JavaScript/TypeScript, or equivalent modern languages, with the ability to read and audit code for vulnerabilities
Integrity and ethical rigor: Consistent history of handling vulnerabilities and disclosures responsibly while engaging constructively with vendors and the research community
Demonstrable written and verbal communication skills, with a track record of producing technical publications, blog posts, and/or conference talks that clearly convey complex security topics

Job Responsibility

Vulnerability Research: Conduct original, hands-on research into application-level, protocol-level, and ecosystem-level vulnerabilities in 1Password’s products and the broader identity security landscape
You will discover, validate, and document novel vulnerability classes and attack chains
Demonstrate Exploitability: Collaborate with peers to develop proof-of-concept exploits and attack demonstrations that validate research findings, illustrate real-world risk, and support engineering teams in understanding and prioritizing remediation efforts
AI & Agentic Security Research: Investigate security risks at the intersection of AI and identity, including prompt injection, data poisoning, and other AI-based attack vectors
Your work will address the emerging challenges of agentic security at the interaction between privileged access management (PAM) and AI systems
Technical Publications & Thought Leadership: Author high-quality research publications, white papers, blog posts, and technical advisories
You will have the opportunity to present findings on podcasts, webinars, and at major security conferences that contribute to 1Password’s reputation as a thought leader in identity security
Community Engagement: Engage actively with the global security research community through responsible disclosure, collaborative research, open-source contributions, and participation in industry forums/events
Cross-functional Collaboration: Partner with Product, Engineering, and Detection teams to translate research findings into actionable security improvements. Provide evidence-based technical guidance that informs product direction and security strategy

What we offer

Maternity and parental leave top-up programs
Competitive health benefits
Generous PTO policy
RSU program for most employees
Retirement matching program
Free 1Password account
Paid volunteer days
Peer-to-peer recognition through Bonusly
Remote-first work environment

Fulltime

Senior Security Researcher

Join a team that’s pushing the frontier of modern security research by combining...

Location

India , Bangalore

Salary:

Not provided

Microsoft Corporation

Expiration Date

Until further notice

Requirements

7+ years of hands‑on experience in security research, threat analysis, malware analysis, or detection engineering, with demonstrated depth in endpoint security
Strong understanding of attacker tradecraft, including persistence, privilege escalation, lateral movement, and defense evasion techniques
Proven experience conducting research on Linux and/or macOS internals, endpoint telemetry, or OS‑level attack surfaces
Proficiency in at least one scripting or systems language (e.g., Python, C/C++, Go, Rust) used for analysis, tooling, or prototyping
Demonstrated ability to independently drive ambiguous, open‑ended investigations from hypothesis to actionable outcome
Strong analytical skills for correlating noisy telemetry into attacker‑relevant signals
Experience translating deep technical findings into clear, decision‑ready insights for engineering and leadership audiences
Proven ability to collaborate effectively across research, engineering, and product teams
Experience mentoring or technically leading other researchers without formal people management responsibilities
High bar for research quality, operational security, and responsible handling of sensitive techniques and data

Job Responsibility

Lead in‑depth investigations of real‑world attacker campaigns, malware, and post‑exploitation techniques across endpoint environments, with emphasis on Linux and macOS platforms
Decompose attack chains, map techniques to MITRE ATT&CK, and maintain high‑fidelity adversary and TTP dossiers that inform protection strategy
Identify emerging attack classes, tradecraft shifts, and detection gaps before they are widely exploited
Design and prototype behavior‑based detections, heuristics, and research‑grade signals that can be operationalized into production protections
Partner with engineering and applied ML teams to translate research findings into scalable, reliable detections with clear acceptance criteria and performance trade‑offs
Evaluate detection efficacy using offline and online telemetry and continuously refine based on real‑world attacker behavior
Contribute to the design of AI‑assisted and agentic investigation pipelines that automate repetitive analysis steps and amplify researcher productivity
Shape how attacker techniques, evidence, and hypotheses are represented in systems that enable campaign discovery and proactive hunting at scale
Ensure research outputs are structured, explainable, and safe for use in automated or semi‑automated workflows
Act as a senior escalation point for complex security incidents, providing expert guidance on attacker behavior, containment strategies, and long‑term mitigation

Fulltime

Senior Manager, Evidence Generation Lead

The medical Director, evidence generation is responsible for supporting strategi...

Location

Belgium , Mechelen

Salary:

Not provided

Alfasigma

Expiration Date

Until further notice

Requirements

Minimum of 7+ years of experience in evidence generation, clinical development, HEOR, or a related field, with at least 5 years of experience in Epidemiology, Health Economics Outcomes Research (HEOR), or/and Health Systems Research
Proven track record of developing and implementing integrated evidence generation plans in the pharmaceutical or biotechnology industry
Experience in design, conduct and oversight of real-world evidence studies ranging from protocol writing to project management oversight and data interpretation and communication
Solid understanding of the cross functional drug development lifecycle and processes (Business Development, clinical trial design, conduct, & endpoint selection, Clinical Operations, Data Management, Biostatistics, and Regulatory)
Demonstrated expertise and experience working with methods for evidence generation using primary and secondary data sources, knowledge of common issues and challenges of implementation, and track-record of successful publications
Demonstrated depth of understanding of observational research methods, regulatory standards, and ability to leverage epidemiologic and data science expertise to meet evolving business needs
Evidence of technical expertise of applying pharmacoepidemiology evidence and insights at the therapy/product level
Ability to explain strengths and limitations of clinical practice datasets — such as electronic health records, claims, clinical data registries, patient generated health data, and other health data sources — in context of designing pharmacoepidemiology study designs
Ability to work successfully in a matrix and quick paced environment
Ability to multitask priorities to align with program objectives

Job Responsibility

Collaborate with cross-functional colleagues to Lead the development and execution of Medical evidence generation strategy and tactics supporting products in development as well as those commercially available, with appropriate prioritization and use of resources ensuring alignment with corporate goals, regional needs, and therapeutic priorities
Oversee the Design and implementation of Integrated Evidence Generation Plans (IEGPs) that incorporate clinical, real-world, and economic data to support product positioning and value demonstration
Scope RWE studies (Regional/National/Academic/Patient/Vendor), selection of new or existing academic (can include: ISR/lIS/NIS)/non-governmental registries (retrospective/prospective), management across various phases from start up, maintenance to final deliverables
Translate (early) trial efficacy to real-world comparative effectiveness as part of early and late phase study planning, identification of subpopulations, and for potential risk-sharing purposes
Design and implement multiple database and/or de novo (e.g. registries) pharmacoepidemiologic studies, as well as literature reviews, intended to provide insight into background epidemiology, disease state regular care, and/or quantify benefits and/or risks potentially associated with Alfasigma products
Project management oversight – ensuring effective design, initiation and implementation of real world evidence studies, while ensuring effective study protocols and plans, managing budget and milestone tracking, and where appropriate contracting with partner organizations
keep abreast on new data and developments in the field, key publications of interest, research methodologies and regulatory standards across the EU and New Markets regions and proactively address HOR strategy changes in collaboration with global and regional teams in anticipation of any trends
Review and provide relevant RWE/HOR inputs to statistical analysis plans and analysis outputs
Understand the legal and compliance environment and drive collaboration with the Legal and Compliance team
Establish metrics to evaluate the effectiveness and impact of evidence generation activities on corporate and product-specific objectives

What we offer

We offer a competitive salary, comprehensive benefits, and extensive opportunities for professional growth and development

Senior Epidemiologist

PURPOSE AND SCOPE: The Senior Epidemiologist at the Renal Research Institute (RR...

Location

United States , Waltham

Salary:

105100.00 - 175100.00 USD / Year

Fresenius Kidney Care Eupora

Expiration Date

Until further notice

Requirements

Advanced Degree (e.g, MS, MPH, or PhD) or equivalent education/degree in biostatistics or epidemiology required. Desirable: Training in health economics, outcomes research, epidemiology, and/or health services research
and/or direct analytics experience at HEOR or Data Management vendors or Pharma and Medical device companies. >5 years related experience with a Master’s degree or >1 years related experience with a Doctoral degree
Strong SAS programming skills

Job Responsibility

Conducts data analysis for RWE studies /requests coming from RWE management, Medical department, and colleagues (e.g, Brand team) who are managing the development of new products, marketed products, and new product indications
Contributes to RWE study design (e.g., observational studies), and objectives for analysis, write analytic programs and ensure quality control conducted on all analyses
Identifies and uses various data sources including FME Corporate Research and RRI databases, and major registries
Collaborates with FME Corporate Research and RRI to analyze FME and RRI data
Supports IT infrastructure for databases and conduct statistical SAS programming
Defines rigorous statistical and epidemiologic methods in observational research and retrospective data analysis
Appropriately document and track all studies and database projects
Consults as internal advisor on statistics and data analysis as it relates to observational research
Provides external communication of analyses in the form of abstracts, posters or manuscripts and conducts the drafting, editing and delivery of medical communication in a timely manner and within the project scope
Ensures that all deliverables are met according to timelines, budget, operational procedures and quality standards

What we offer

Medical, dental, and vision insurance
401(k) with company match
paid time off
parental leave
healthcare
continuing education
collaborative environment

Graduate Software Engineer

A high-growth Cambridge technology company is looking for an exceptional Graduat...

Location

United Kingdom , Cambridge

Salary:

Not provided

Oho Group Ltd

Expiration Date

Until further notice

Requirements

Outstanding Computer Science fundamentals and strong Object-Oriented Programming skills
A 2:1 or above from Cambridge, Oxford, Imperial, or another leading university in Computer Science, Mathematics, Engineering, Physics, or a related STEM discipline
Exceptional academic achievement, including excellent A-Level results
Evidence of technical excellence through internships, research, hackathons, competitions, open-source work, or ambitious personal projects
Genuine curiosity, ambition, and the desire to become a world-class software engineer
A growth mindset and the drive to thrive in a high-performance environment surrounded by equally ambitious peers

Job Responsibility

Take ownership of meaningful projects from day one
Work on challenging, real-world engineering problems that will rapidly develop your skills
Collaborate directly with senior engineers and technical leaders on core product decisions
Contribute to products that have a genuine impact

Fulltime

Senior Platform Product Designer

As our Senior Platform Product Designer, you will combine genuine product design...

Location

Switzerland , Rolle

Salary:

Not provided

SOPHiA GENETICS

Expiration Date

Until further notice

Requirements

A track record as a senior product or platform designer in environments where users are domain experts — clinical, scientific, or technical SaaS where workflows are genuinely complex and simplification is not the answer
A portfolio of shipped work showing product judgment: hard tradeoffs, designs evolved through validation, and clear evidence that your involvement changed what got built
Experience designing for multiple, distinct user groups within a single platform — and keeping the product coherent across them
Experience designing information-dense, data-heavy interfaces: tables, filters, multi-step clinical or scientific workflows, multimodal data views
Experience in regulated environments (HealthTech, MedTech, scientific software) is a strong advantage
Strong design system thinking
Comfortable working close to code and close to product: you can author requirements and acceptance criteria, hold a meaningful conversation with engineers about implementation constraints, and build prototypes that go beyond static mockups
Rapid prototyping fluency — including with modern AI-assisted tooling — used in service of faster clinical validation, not as an end in itself
Familiar with the engineering vocabulary of data-intensive platforms: APIs, data models, performance, security, accessibility
Genuine curiosity about the domain — clinical genomics, imaging, and real-world data are technically rich and humanly consequential

Job Responsibility

Own cross-platform design problems
Lead the design of major DDM platform workflows across the full product surface
Define and evolve the cross-surface interaction patterns that give the platform coherence
Govern and evolve the DDM design system in collaboration with engineering
Work at expert-user depth - across diverse user groups
Conduct research with users across the platform’s range
Design for appropriate complexity — not for consumer simplicity
Balance clinical workflow fidelity with IVD regulatory constraints
Build interactive prototypes to compress the time between concept and clinical feedback
Run validation sessions with clinical users, oncologists, and pharma partners early and continuously

What we offer

Sickness and Accident coverage through Helsana
Meal Vouchers at 90CHF PM with our partner cafeteria
A fun and engaging work environment, with Rest & Entertainment space, full stocked free coffee machine and free fruit/snacks
Free parking in an easy to access location
A strong social committee whose purpose is to make SOPHiA GENETICs both enjoyable as well as rewarding
As our global HQ, you’ll have direct interaction and exposure to senior leadership and our executive team locally

Fulltime

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Senior Researcher - Real World Evidence

Job Description

Job Responsibility

Requirements

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