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CK Group Logo CK Group · Research and Development

Senior Research Scientist, Mass Spectrometry

United Kingdom, Abingdon Contract work · Job Posted February 20, 2026
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Job Description

CK Group are recruiting for a Senior Research Scientist, Mass Spectrometry to join a global biotechnology company, on a contract basis for 12 months.

Job Responsibility

  • Design, develop, and validate robust small molecule MS-based assays for drug discovery
  • Optimize assay conditions to ensure high sensitivity, specificity, and reproducibility for small molecule detection and quantification
  • Collaborate with structural biology and biophysics teams to integrate MS data with structural and biophysical insights
  • Work closely with medicinal chemists, biologists, and other scientists to align assay development with project goals
  • Ensure compliance with laboratory SOPs and detailed record keeping in an electronic notebook
  • Maintain, operate, and troubleshoot LCMS instrumentation for routine and novel assays

Requirements

  • Relevant Ph.D. or equivalent experience with a proven track record of small molecule mass spec delivery
  • Experience running and analysing quantitative small molecule mass spec assays
  • Practical experience working with triplequad MS platforms
  • Hands-on experience troubleshooting complex instrumentation
  • It is essential that applicants hold entitlement to work in the UK

Nice to have

Experience of small molecule Affinity Selection Mass Spectrometry (AS-MS) is desirable

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