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AbCellera Biologics Logo AbCellera Biologics · Research and Development

Senior Research Scientist – Pharmacokinetics

Canada, Vancouver Employment contract 112000.00 - 132000.00 CAD / Year · Job Posted May 29, 2026
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Job Description

We are seeking a highly motivated Senior Research Scientist with a strong understanding of pharmacokinetics and bioanalytical methods to join our multidisciplinary Pharmacokinetics (PK) team. Based in Vancouver, you will be instrumental in bridging the gap between discovery and the clinic, specifically driving the bioanalytical and ADME strategies and execution with a focus on antibody drug conjugate (ADC) programs. In this role, you will collaborate with cross-functional teams, including non-clinical safety, modeling and simulations, protein sciences, and the clinical and regulatory teams, to support the progression of our projects from discovery to development.

Job Responsibility

  • Leading external activities for establishing, qualifying, and validating ligand-binding assays and LC-MS/MS methods to support the preclinical and clinical development of novel ADC therapeutics, including measurement of drug concentration and anti-drug antibodies
  • Characterizing the ADME profile for ADC candidates, including assessing the drug-drug interaction (DDI) potential of released small molecule payloads
  • Leading the analysis, interpretation, and reporting of PK/ADME data to support regulatory filings (IND/CTA), including authoring and reviewing high-quality study reports, briefing packages, and regulatory documents
  • Collaborating with cross-functional project teams where you'll represent the PK function, and interacting externally with CROs or consultants
  • Training and mentoring scientists

Requirements

  • Expert in the design, development, and phase-appropriate qualification/validation of LC/MS-MS bioanalytical assays to support preclinical and clinical development
  • Demonstrated expertise in authoring sections of regulatory submissions
  • Comfortable with non-compartmental data analysis (WinNonlin), and have a good understanding of PK parameters
  • 8+ years of relevant industry experience in addition to a PhD in Biology, Pharmacology, or related discipline
  • candidates with a MSc and 10+ years of industry experience will also be considered
  • Genuinely curious and energized by working with teammates to discuss innovative ideas in a highly collaborative and fast paced environment
  • Excel in documentation and organizational skills and clearly communicate scientific and technical concepts both verbally and in writing

Nice to have

Direct experience with PK profiling of ADCs (considered a strong asset)

What we offer

  • Equity
  • Annual bonus dependent on team and company performance
  • 6% (non-match) RRSP contribution
  • CAD $1,500 annual Active Lifestyle Allowance
  • Annual vacation
  • Opportunity for flexible work arrangements
  • Professional development opportunities
  • Comprehensive health benefits
  • Scientific and technical mentorship
  • Strong sense of community and connections through work, clubs, and socials
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