Senior/Principal Scientist, Platform Chemistry

We are looking for a highly motivated Senior Scientist to play a key role in the development and application of Orbis Medicines’ next-generation nCycle platform at the laboratory in Copenhagen. You will take an active role in the design and synthesis of compound libraries for hit identification and hit optimization in nCycle projects, working at the interface of chemical innovation, platform development, and early drug discovery. In this role, you will contribute directly to the design, optimization, and execution of complex macrocyclic synthesis strategies, with a strong focus on quality. You will work hands-on in the laboratory using automated synthesis platforms and advanced laboratory instrumentation to troubleshoot and optimize synthesis workflows. In addition, you will help establish best practices for the implementation and use of new technologies and workflows. As a scientific driver within the Platform Chemistry team, you will work closely with technicians, fellow scientists, and cross-functional colleagues, including AI and computational drug design scientists. Your responsibilities will also include analyzing screening data, identifying hit compounds for resynthesis, and contributing to the maintenance and organization of laboratory equipment and chemical inventory. This role offers a unique opportunity to combine deep scientific thinking with practical, hands-on laboratory work, actively participating alongside the team.