Senior / Principal Machine Learning Scientist Jobs

Altos Labs

Location:
United States, Redwood City ▼
San Diego

Category:
Research and Development

Contract Type:
Not provided

Salary:

260950.00 - 509450.00 USD / Year

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Job Description:

Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life. As a Senior or Principal Machine Learning Scientist, you will play a prominent role in developing generative AI/ML models for multi-modal, multiscale biology from virtual cells to agentic target assessment.

Job Responsibility:

Pioneer novel machine learning methodologies and statistical frameworks
Contribute to setting the long-term technical vision and research strategy for a core domain
Translate your deep understanding of the mathematical and theoretical underpinnings of cutting-edge AI research into high-impact applications
Design, implement, and optimize large-scale machine learning systems
Develop and manage efficient distributed training strategies across multiple GPUs and compute clusters
Develop robust approaches for multi-modal data integration and cross-domain mapping
Apply computational thinking to solve problems in drug target identification, compound assessment, and prediction of cellular perturbation responses
Lead the full ML development lifecycle
Act as a key technical mentor to Machine Learning Scientists and Engineers

Requirements:

Ph.D. in Machine Learning, Computer Science, Artificial Intelligence, Statistics, or a related quantitative field
6+ years of relevant post-PhD work experience in either an academic or industry setting
Proven experience developing and applying complex machine learning models
A strong track record of leading and publishing innovative, peer-reviewed research in top-tier ML conferences or high-impact scientific journals
Excellent scientific communication skills
Expertise in several of the following: deep learning, reinforcement learning, generative models, language models, computer vision, Bayesian inference, causal reasoning & inference, transfer & multi-task learning, graph neural networks, active learning, hybrid mechanistic/ML models
Proven experience applying sophisticated ML techniques to molecular and cell biological data sets

Nice to have:

Experience in cell health and rejuvenation related research area
Experience in the application of machine learning methods to biological data
Experience in computational approaches to drug discovery
Experience with software development methodologies and open-source software

Additional Information:

Job Posted:
December 05, 2025

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Senior / Principal Machine Learning Scientist