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Senior NGS Bioinformatician

Switzerland, Rolle · Job Posted February 07, 2026
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Job Description

You will lead data exploration efforts to address practical questions that arise during product development. You will work with diverse datasets that vary by gene panel, sample type, enrichment technology, sequencing platform, and more. Your work will involve assessing NGS kit and chemistry performance, evaluating the analytical accuracy of SOPHiA GENETICS products, and conducting in-depth, product-focused analyses. Your insights will directly contribute to the evolution of our products.

Job Responsibility

  • Run SOPHIA GENETICS NGS pipelines in default mode
  • Modify some scripts/modules manually for research purpose
  • Understand the functions of each script/module in SG pipeline
  • Carry out quality assessment and analytical performance on different chemicals or platforms by established metrics
  • Perform data exploration on other practical questions related to product feasibility study to provide actionable insights
  • Explore new technical/biological features (e.g. UMI diversity) in deep to provide scientific insights and present the results logically
  • Analyze dataset from collaborators and provide exploration results on time
  • Join the discussion with collaborators for project progress and present the results
  • Prepare NGS analysis results and present to customers and prospective clients at conferences and workshops

Requirements

  • Minimum of 4 years Post-Doc experience in Bioinformatics, Computational Biology or related field
  • Or PhD degree and equivalent relevant working experience
  • Extensive experience with targeted sequencing data analysis
  • Hands on experience analyzing NGS data
  • Strong background in hematologic cancer biology is a strong plus
  • Extensive experience of data analysis in Biopharma/CDx development is a strong plus
  • Excellent communication & presentation skills (English is a must, any other language is an asset)

Nice to have

  • Strong background in hematologic cancer biology
  • Extensive experience of data analysis in Biopharma/CDx development
  • Any other language besides English

What we offer

  • Sickness and Accident coverage through Helsana
  • Meal Vouchers at 90CHF PM with our partner cafeteria
  • A fun and engaging work environment, with Rest & Entertainment space, full stocked free coffee machine and free fruit
  • Free parking in an easy to access location
  • A strong social committee whose purpose is to make SOPHiA GENETICs both enjoyable as well as rewarding
  • Direct interaction and exposure to senior leadership and our executive team locally

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