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Senior MES Engineer

United States, Raleigh · Job Posted March 21, 2026
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Job Description

We are seeking a Senior MES Engineer to support the expansion of our Manufacturing Execution Systems (MES) practice and provide on-site engineering support for pharmaceutical manufacturing operations in the RTP area. This role will serve as a technical leader, delivering MES solutions that support manufacturing efficiency, data integrity, and regulatory compliance in GMP environments.

Job Responsibility

  • Provide on-site and remote MES engineering support for pharmaceutical manufacturing operations
  • Lead the design, configuration, and deployment of MES solutions in GMP-regulated environments
  • Serve as a technical subject matter expert for MES platforms, supporting production, quality, and IT stakeholders
  • Support MES lifecycle activities including requirements gathering, system configuration, testing, validation, deployment, and operational support
  • Lead or contribute to change management, impact assessments, and controlled system updates
  • Support investigations, root cause analysis, and issue resolution related to MES applications
  • Lead, mentor, and grow a team of MES engineers, providing hands-on technical guidance, career development support, and day-to-day leadership to build a strong and scalable MES practice
  • Drive the continued growth of the MES practice by defining standards, establishing best practices, and providing technical leadership to ensure consistent, high-quality MES solution delivery
  • Contribute to the growth of the MES practice through standardization, best practices, and technical leadership
  • Collaborate closely with Sales and Business Development to support pre-sales activities, shape MES solutions, and identify new opportunities that expand the MES practice and overall business

Requirements

  • Bachelor’s degree in Engineering, Computer Science, Information Systems, or a related technical discipline
  • 7+ years of experience supporting or implementing MES solutions in pharmaceutical, biotech, or life sciences manufacturing environments
  • Strong knowledge of GMP regulations, data integrity principles, and validated systems
  • Hands-on experience with one or more MES platforms (e.g., Emerson Syncade, Rockwell PharmaSuite, Körber PAS-X, or similar)
  • Experience with MES configuration, integration, and support across manufacturing operations
  • Strong troubleshooting, analytical, and problem-solving skills
  • Ability to work effectively in an on-site, client-facing role
  • Excellent written and verbal communication skills

Nice to have

  • Prior experience supporting large pharmaceutical manufacturing environments
  • Experience with system validation, CSV, and regulated documentation practices
  • Knowledge of ISA-88 / ISA-95 standards and manufacturing workflows
  • Experience integrating MES with ERP, automation, or data historian systems

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