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Senior Medical Director, Bladder/RCC

United States, New York City 214900.00 - 341100.00 USD / Year · Job Posted February 20, 2026
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Job Description

The Senior Medical Director will be responsible for leading several US Medical Affairs activities in support of Bladder Cancer.

Job Responsibility

  • Provide deep expertise in bladder cancer disease state and treatment, with a focus on the evolving landscape in muscle-invasive bladder cancer
  • Provide strategic medical input for enfortumab vedotin in collaboration with Alliance partners, extended medical team, and cross functional colleagues to support aligned objectives
  • Ensure US launch readiness for new assets/indications
  • Develop and execute short and long-term US Medical plans, aligned with overall business goals
  • Work closely with Global Medical Affairs and other cross-functional colleagues, as appropriate, ensuring that the US Medical Affairs plan is aligned with brand strategies to support successful pre-launch, launch & post-launch medical initiatives
  • Understand and integrate the needs/perspectives of patients and HCPs into Medical plans & tactics
  • Responsible to lead strategic medical partnerships with key external organizations from a bladder cancer portfolio perspective
  • Strategic Medical leadership in ongoing sponsored study clinical research
  • Responsible to oversee strategic fit and operational excellence of US ISRs from a bladder cancer portfolio perspective
  • Oversee and coordinate medical input into brand strategies and tactics, aligning on US regional medical needs
  • Lead the development and timely execution of medical strategies and tactics
  • Participate, as needed, on Medical sub-team meetings and activities
  • Partnership with Global Medical Affairs to assure US is represented in Global Medical decisions and ensuring GLocal coordination in all activities
  • Provide clear medical input on promotional and sales training materials, in partnership with Legal, Regulatory and Marketing colleagues, to ensure compliant, accurate, fair-balanced and high-quality content of all commercial materials
  • Provide leadership for the development and implementation of customer insight planning (including Advisory Boards) to gather expert guidance to advise medical planning
  • Develop strategies and manage Investigator-Initiated Research program, Clinical Research Collaborations and analyses of Real World Data
  • Develop and advocate for Phase IV lifecycle clinical trial strategies and concepts to support regional medical business needs
  • Collaborate with Global Scientific Communications and Clinical Development on key governance committee to support development of strategic global and regional publication plans
  • Participate in data analysis efforts, and lead or participate in manuscript, abstract, and poster development
  • Represent regional medical on internal safety committees, safety analysis and interpretation of clinical and RWD, guidance for safety updates, issues pertaining to regional business
  • Provide regional medical leadership, support and guidance for new labels, label updates and responses to regulatory requests
  • Partner with expert thought leaders and societies to support regional Medical business goals, including manuscript generation, research partnerships, fellowships, expert guidance, and competitive insight
  • Provide primary medical leadership & support for regional medical congresses
  • Effective leadership within team matrix, excellent interpersonal skills
  • Responsible for developing and coaching other team members as requested
  • Support a high-functioning and performance culture for team
  • Serve as a medical/clinical expert in the diagnosis and treatment of patients with bladder cancer to bring the voice of patients & physicians to efforts and initiatives

Requirements

  • PhD, PharmD, DVM professional degree
  • 8 or more years experience in either pharmaceutical industry, academic centers, clinical practice, or a combination of these
  • Experienced in the diagnosis and treatment of patients with bladder cancer within the US Healthcare System
  • Headquarters and launch experience strongly preferred
  • Knowledge and experience in bladder cancer preferred
  • Understanding of the drug development process & experience with efficiently managing investigator-initiated research
  • Knowledge of health care economics and its impact on medical decision making desired
  • Highly motivated with demonstrated track record of high performance and excellence
  • Strong strategic skills including creativity and effectiveness in proactively identifying and addressing challenges
  • Strong interpersonal skills and excellent verbal communication and presentation skills
  • Proven ability to facilitate open discussion and debate among key stakeholders and build internal and external relationships
  • Well-organized with the ability to be flexible, prioritize multiple demands, and effectively lead in a matrix organization
  • Capable of comprehending and communicating a large amount of scientific information in a clear & concise manner
  • Ability to work flexible hours
  • Ability to travel up to 25%
  • Long hours seated at a computer
  • This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week
  • This position requires permanent work authorization in the United States

Nice to have

  • Headquarters and launch experience strongly preferred
  • Knowledge and experience in bladder cancer preferred
  • Knowledge of health care economics and its impact on medical decision making desired

What we offer

  • Eligibility for participation in Pfizer’s Global Performance Plan with a bonus target of 22.5% of the base salary
  • Eligibility to participate in our share based long term incentive program
  • 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution
  • Paid vacation, holiday and personal days
  • Paid caregiver/parental and medical leave
  • Health benefits to include medical, prescription drug, dental and vision coverage
  • Relocation assistance may be available based on business needs and/or eligibility

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