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Senior Manager, Reliability Engineering & Work Management

United States, Holly Springs Employment contract 148715.15 - 201202.85 USD / Year · Job Posted June 04, 2026
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Job Description

Join Amgen’s Mission of Serving Patients. At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Job Responsibility

  • Lead and develop a multi-functional engineering operations organization responsible for work order administration, CMMS governance, maintenance planning and scheduling, reliability engineering, central inventory management, and KPI reporting
  • Lead the Central Inventory (equipment spare parts) program working closely with the Internal Service Provider as it relates to the overall MRO process supporting the site
  • Lead the site reliability program, aligning on the network approach for the Amgen North Carolina reliability roadmap, implementing initiatives and own engineering KPIs and business reporting on program and site equipment health
  • Establish long-range maintenance and asset reliability strategies aligned with site operational goals, regulatory compliance requirements, and enterprise engineering standards
  • Identify opportunities for continuous improvement, recommend solutions, and manage implementation of initiatives to improve planning and scheduling accuracy and adherence and overall asset management program
  • Collaborate with key customers and support groups regarding preventative maintenance activities and on time completion as well as manage aging work order backlog
  • Collaborate with corporate network groups to improve planning and scheduling performance in addition to improving programs within CMMS, Central Inventory, and Reliability to meet business needs
  • Provide direct supervision and oversight of work order safety programs and planning procedures
  • Experience working in a regulated environment (e.g. cGMP, OSHA, EPA, etc.), experience interacting with regulatory agencies and inspectors, and familiarity with GMP quality systems/processes such as change control, non-conformances, corrective and preventative actions, and qualifications/validation
  • Strong leadership, technical writing, and communication/presentation skills
  • Work schedule flexibility as required to support 24/7 operations, requiring occasional after-hours engineering coverage

Requirements

  • High school diploma / GED and 12 years of engineering, maintenance, reliability, or CMMS experience OR Associate’s degree and 10 years of engineering, maintenance, reliability, or CMMS experience OR Bachelor’s degree and 8 years of engineering, maintenance, reliability, or CMMS experience OR Master’s degree and 6 years of engineering, maintenance, reliability, or CMMS experience OR Doctorate degree and 2 years of engineering, maintenance, reliability, or CMMS experience
  • minimum of 2 years experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources

Nice to have

  • Bachelor’s or Master’s degree in Engineering, Reliability Engineering, Industrial Engineering, or related technical field
  • 8+ years of experience in pharmaceutical, biotechnology, or other highly regulated manufacturing industries
  • 5+ years of leadership experience in maintenance, reliability engineering, facilities engineering, or asset management
  • Demonstrated expertise with CMMS platforms such as SAP PM, Maximo, or equivalent systems
  • Demonstrated skills, knowledge and experience utilizing a computerized maintenance management system
  • Strong understanding of reliability engineering principles and asset lifecycle management
  • Experience leading MRO inventory and spare parts optimization programs
  • Knowledge of predictive maintenance technologies and Industry 4.0 systems
  • Experience managing integrated service providers and contractor organizations
  • Proven ability to lead continuous improvement and operational excellence initiatives
  • Strong financial acumen including budget management, forecasting, and cost optimization
  • Experience with KPI development, data analytics, and business intelligence reporting tools
  • Demonstrated ability to influence across functions and communicate effectively with senior leadership
  • Strong understanding of cGMP regulations, EHS requirements, and data integrity expectations
  • Ability to work within Microsoft Excel and Brio or other Data query software
  • Proven troubleshooting, problem solving and investigational skills
  • Demonstrated interpersonal and facilitation skills and ability to work in a collaborative team-based environment
  • Ability to work with minimum direction
  • Ability to manage multiple tasks and effectively set priorities

What we offer

  • A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
  • A discretionary annual bonus program
  • Stock-based long-term incentives
  • Award-winning time-off plans
  • Flexible work models where possible

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