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Senior Manager Clinical Operations and Strategic Alliances

United States, Pleasanton 173100.00 - 234100.00 USD / Year · Job Posted March 04, 2026
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Job Description

The Sr. Manager, Clinical Operations and Strategic Alliances reporting to the Director, Business Development and Strategic Partnerships will drive the operational execution and strategic management of high-impact alliances central to 10x Genomics’ effort to advance future diagnostic applications for single cell and spatial technologies.

Job Responsibility

  • Study Execution: Manage the operational execution of large-scale, longitudinal clinical research studies according to established agreements with academic institutions
  • Timeline & Risk Management: Own and drive clinical research study timelines, deliverables, and operational plans ensuring adherence to sampling schedules
  • identify operational risks regarding enrollment, setup, or logistics early, implementing mitigation strategies to maintain study integrity
  • Sample Logistics & Chain of Custody: Establish and enforce auditable procedures for sample collection, tracking, and chain of custody, ensuring compliant transport from clinical sites to 10x Genomics laboratory
  • Budget & Resource Oversight: Manage the study budgets, including the oversight of reimbursement, equipment provisioning, and consumables provided to partner sites
  • Regulatory & Quality Compliance: Ensure all study activities comply with IRB protocols, patient consent requirements, and GCLP/CLIA standards where applicable
  • Partnership Management: Manage a diverse, high-value portfolio of academic collaborations and strategic partnerships to ensure all projects and agreements track toward established milestones and outcomes
  • Governance Management: Ensure transparent communication, effective decision-making, and rapid conflict resolution between internal teams and external partners
  • lead and facilitate Joint Steering Committees (JSCs) and cross-functional governance meetings as needed
  • Stakeholder Management: Act as the primary liaison between internal teams and key stakeholders at relevant academic institutions and industry partners to foster strong, collaborative relationships that drive engagement and performance
  • Contract Lifecycle Management: Oversee compliance with contractual obligations, milestones, and deliverables, working closely with Legal, Finance, and Business Development to drive contract amendments or renewals as needed

Requirements

  • An Advanced degree (M.S., PharmD, Ph.D., M.B.A.) in a Life Science, Clinical, or related field is required
  • 8+ years of relevant industry experience with 4-5 years of experience in Clinical Operations and Alliance / Program Management within the diagnostics, biotechnology, or pharmaceutical industry
  • Direct experience managing research studies involving large numbers of patient samples and complex molecular testing or biomarkers
  • Deep understanding of clinical study execution, site management, and the complexities of clinical sample logistics and chain of custody
  • Direct experience in managing high-value strategic alliances and driving value through the successful execution of collaborative research, development, or commercialization agreements
  • Demonstrated ability to manage competing priorities, swiftly resolve complex operational problems, and drive tangible results

Nice to have

  • Thrives in a fast-paced environment with a ‘roll up your sleeves and get it done’ mentality
  • Excellent at communicating, organizing, and leading external stakeholders and internal cross-functional teams to achieve desired outcomes
  • Comfortable leading through ambiguity and change
  • focusing on finding practical solutions and driving clarity to maintain program momentum
  • Exceptional at building strong, collaborative relationships with diverse stakeholders, including external investigators, and internal technical and executive teams
  • Startup or small biotech experience
  • Familiarity with CLIA/CAP standards as they relate to samples sent to a centralized testing laboratory is preferred

What we offer

  • Equity grants
  • Comprehensive health and retirement benefit programs
  • Annual bonus program or sales incentive program
  • Generous time off
  • Competitive and comprehensive health benefits package
  • Easy-to-use benefits that promote wellbeing and make your life easier
  • Family friendly policies like parental leave
  • Award-Winning Workplace

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