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Senior Machine Learning Engineer - Forecasting

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Amgen

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Location:
United States , Los Angeles

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Contract Type:
Employment contract

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Salary:

156190.05 - 211315.95 USD / Year

Job Description:

We are seeking a Senior Machine Learning Engineer, Forecasting to join the Forecasting team within the AI & Data organization. This role will design, build, deploy, and maintain scalable machine learning systems that power forecasting capabilities and uncertainty-aware decision support across the company. This senior member of the team will work cross-functionally to translate advanced forecasting methods into reliable, production-grade solutions that support critical business processes and help Amgen deliver on its 'every patient, every time' mandate. The role is particularly well suited to a strong engineer who is excited about building robust ML infrastructure, productionizing state-of-the-art forecasting models, and enabling decision-support solutions that inform multi-horizon planning and business decision-making.

Job Responsibility:

  • Design, build, and maintain scalable machine learning systems and forecasting pipelines to support demand forecasting across near-, medium-, and long-term planning horizons
  • Productionize advanced statistical, Bayesian, and machine learning forecasting models, including training, validation, deployment, and lifecycle management
  • Build and optimize data pipelines, feature engineering workflows, and batch and real-time inference systems using large, complex datasets
  • Own the end-to-end ML engineering lifecycle, including solution design, prototyping, model integration, testing, deployment, monitoring, observability, and continuous improvement
  • Develop robust MLOps capabilities, including model versioning, CI/CD, automated retraining, performance monitoring, drift detection, and rollback strategies
  • Partner closely with data scientists and business stakeholders to operationalize forecasting, simulation, and scenario-analysis capabilities that support strategic decision-making
  • Establish and promote software engineering best practices, including code quality, documentation, reproducibility, and system reliability
  • Research and evaluate emerging tools, platforms, and methodologies in machine learning engineering, forecasting, and AI for potential application to business problems

Requirements:

Doctorate degree OR Master's degree and 2 years of applying data science in enterprise environments experience OR Bachelor's degree and 4 years of applying data science in enterprise environments experience OR Associate's degree and 8 years of applying data science in enterprise environments experience OR High school diploma / GED and 10 years of applying data science in enterprise environments experience

Nice to have:

  • 6+ years of experience in machine learning engineering, software engineering, or a related field, with a demonstrated track record of deploying production ML systems that deliver business value
  • Strong experience building and maintaining end-to-end ML pipelines and production systems for forecasting or other predictive modeling use cases
  • Expertise in model serving, and operationalizing probabilistic, Bayesian, or predictive models in production environments
  • Strong programming skills in Python and SQL, with experience using tools such as scikit-learn, PyTorch, TensorFlow, and orchestration or workflow tools for ML pipelines
  • Experience with cloud platforms, distributed data processing, containerization, and ML deployment patterns
  • Strong understanding of software engineering fundamentals, including system design, testing, performance optimization, and maintainability
  • Strong collaboration and communication skills, with the ability to work effectively across technical and non-technical teams
  • An intellectually curious self-starter who can take ambiguous problems and build scalable solutions from the ground up
  • Experience building and deploying forecasting models for biotech/pharma use cases with knowledge of healthcare commercial concepts such as payer/provider dynamics, formulary access, and coverage
  • Experience partnering closely with data scientists to translate advanced statistical or machine learning models into reliable production services
  • Experience leveraging machine learning and forecasting systems in retail, consumer goods, supply chain, or manufacturing applications
  • Familiarity with model monitoring, explainability, and governance requirements in regulated or high-impact business environments
What we offer:
  • A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans
  • Flexible work models where possible

Additional Information:

Job Posted:
May 10, 2026

Employment Type:
Fulltime
Work Type:
Remote work
Job Link Share:

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