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Amgen Dun Laoghaire (ADL) is looking for a Senior Equipment Process Engineer to join our Drug Product Engineering team to support commercial aseptic Drug product filling on site. Amgen Dun Laoghaire (ADL) is a 37,000 square metre aseptic drug product operations facility, specialising in secondary manufacturing activities – Formulation, Vial/Syringe Filling, Lyophilisation and Packaging. This position will be responsible for performance drug product equipment on site. The Senior Equipment Process Engineer will report to the Engineering Lead and should have knowledge and proficiency in the use of statistical analysis tools, continuous improvement methodologies, problem solving and applied engineering skills relating to mechanical, electro-mechanical and associated automation systems. The Senior Equipment Process Engineer will also have full overall responsibility for the reliability and life cycle of equipment.
Job Responsibility:
Support a safe working environment by complying with all pertinent environmental health/safety practice, rules and regulations
Ownership of equipment/systems in a GMP regulated manufacturing setting that support the Drug Product manufacturing processes
Monitoring of day-to-day performance, including trend analysis of all performance aspects of their system and equipment to identify and proactively manage performance trends
Lead and support system improvements, development of detailed specifications, engineering documents and standard operating procedures
Lead technical root cause analysis, incident investigations and after action reviews when troubleshooting issues related to manufacturing equipment/systems
Lead solving complex problems, project management, equipment lifecycle management and operational excellence initiatives related to their systems / equipment
Develop and manage change control requests per established SOPs and processes
Support new product introductions or new technology introductions by performing engineering assessments, implementation of system changes and supporting engineering runs
Communicating with key stake holders, in a responsive manner to ensure they are kept informed on all engineering activities
Working in a collaborative manner within cross functional work centre team, and contributes to investigations, Non-Conformance and CAPA closure
Responsible for a structured maintenance schedule which will align with the manufacturing schedule to minimise downtime. This includes routine PM’s and long term planning for vendor support on site and the procurement of major spare part assemblies in a timely manner to support larger overhauls
Responsible for the development and maintenance of spare parts lists for their system and appropriate levels of spares are maintained
Requirements:
Bachelor's degree in Engineering (Mechanical, Manufacturing, Mechatronics, Electrical or Chemical)
Manufacturing experience in a regulated environment
Experience in the use of statistical analysis tool & continuous improvement methodologies
Problem solving and applied engineering skills relating to mechanical, electro-mechanical and associated automation systems
Nice to have:
Manufacturing experience in biopharmaceutical Formulation/Fill/Finish or Active Pharmaceutical Ingredient (API) facilities
Direct experience supporting either Vial or Syringe Filling equipment
Solid leadership, technical writing, and communication/presentation skills
Experience in change control, non-conformance, corrective and preventative actions, and validation practices
Experience in developing strategies for new product introduction and new technology deployment
Ability to translate strategic opportunities and emerging technology solutions into tangible pragmatic executable plans
Ability to influence the development of business area strategy and engineering/equipment strategy where appropriate
Development and presentation of project plans to senior management
Day to day vendor management and contract negotiations with focus on equipment suppliers
Independent, self-motivated, organized, able to multi-task in project environments and skilled in communication and collaboration
Team player, prepared to work in and embrace a team-based culture that relies on collaboration for effective decision-making
What we offer:
Competitive salary structure
Generous Total Rewards Plan for staff and eligible dependents
Comprehensive employee benefits package, including retirement and savings plan with generous company contributions, group medical, life and disability insurance
Discretionary annual bonus program
Exceptional learning, development and career advancement opportunities