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Senior Engineer: Mathematical Modeling and Simulation

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Amgen

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Location:
United States , Cambridge

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Category:
IT - Software Development

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Contract Type:
Not provided

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Salary:

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Job Description:

Amgen's Combination Product Operations Digital and Data Strategies group is a process development team that develops and deploys innovative advanced simulation technologies towards improved process understanding, robustness and monitoring, and prediction and optimization of the manufacturing of combination products. In this vital role you will support the team by incorporating physics and empirical techniques to develop rigorous finite element models (FEM) and numerical models of drug delivery devices (in-silico modeling assets) and improving the way Amgen manages and uses in-silico models to enhance decision making within the organization. The candidate will apply engineering principles to develop efficient and trustworthy models addressing a wide variety of challenging problems associated with advanced material modelling, device design, characterization, verification, validation, manufacturing and tolerance analysis.

Job Responsibility:

  • Implementing explicit and implicit FEM structural models
  • Applying engineering principles like kinematic, structural, and tolerance analysis combined with material characterization and testing to create in-silico models
  • Continuous improvement of in-silico models, managing the lifecycle of the model
  • Demonstrating critical and analytical thinking skills to explore new opportunities in in-silico and data-driven computational models
  • Simulate complaints and real-world issues within lifecycle of combination products
  • Providing positive leadership and delivering work in a fast-paced, multi-project, cross-functional environment
  • Model ownership, responsible for developing and managing backlog of in-silico product projects

Requirements:

  • Doctorate degree
  • OR Master’s degree and 2 years of Engineering experience
  • OR Bachelor’s degree and 4 years of Engineering experience
  • OR Associate’s degree and 8 years of Engineering experience
  • OR High school diploma / GED and 10 years of Engineering experience

Nice to have:

  • Finite element model experience with a commercial platform like SIMULIA, ANSYS, ALTAIR or COMSOL
  • Experience in explicit FEM modelling and non-linear structural models
  • contact modelling, large deformations, plasticity, and hyperelasticity
  • Knowledge of statistic and robustness analysis principles
  • Skilled in programming in Python, and/or MATLAB for engineering purposes
  • Scripting using commercial software codes like abaqus user subroutines, Tcl/Tk
  • Experience with combination products and device regulatory requirements, medical device development and design controls, and knowledge of process controls
  • Excellent communication, presentation, and technical documentation skills
  • Intellectual curiosity with ability to learn new concepts/frameworks, algorithms, and technology rapidly
  • Ability to manage multiple competing priorities simultaneously and work in highly collaborative, cross-functional environments
What we offer:
  • A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans

Additional Information:

Job Posted:
January 13, 2026

Work Type:
On-site work
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