Senior Director, Safety Job at Crusoe (San Francisco)

Senior Medical Director / Medical Director, Pharmacovigilance

The Medical Director of Pharmacovigilance (PV) will provide clinical/scientific/...

Location

United States , Cambridge, MA

Salary:

210000.00 - 375000.00 USD / Year

Beam Therapeutics

Expiration Date

Until further notice

Requirements

MD required, Board certification preferred with 15+ years of experience
5+ years of pharmacovigilance experience
Experience in cell or gene therapy preferred
Experience as safety lead for asset/approved drug product e.g. Global Safety Lead
Oversight experience of global medical safety activities
Demonstrated knowledge of global PV regulatory environment
Working knowledge of industry standard safety databases (ARGUS and ARISg)
Knowledge of MedDRA dictionary
Excellent knowledge of drug development process
Experience reviewing cumulative safety data

Job Responsibility

Provide dynamic leadership, strategic direction and governance of patient safety and PV risk management activities
Lead signal detection and risk management activities for assigned products
Lead proactive and ongoing analysis and interpretation of non-clinical data, clinical, post-marketing, scientific literature
Lead PV during interactions with Regulatory Authorities (RA)
Perform individual case safety report (ICSR) medical review
Lead multidisciplinary Safety Management Committee (SMC) and Executive Safety Committee (ESC)
Serve as PV SME in support of regulatory filing activities
Collaborate with cross functional team
Address internal/external safety-related requests
Provide guidance regarding Statistical Analysis Plans

Fulltime

Health & Safety Director

Incredible opportunity to join the senior leadership team of this £50m turnover ...

Location

United Kingdom

Salary:

Not provided

Blue Book Partners

Expiration Date

Until further notice

Requirements

Demonstrable senior-level H&S experience within civils, enabling works, construction, or infrastructure
Gravitas to assume the role of Safety Leader/number one in a contractor with a turnover of £30m plus
Chartered membership of IOSH (CMIOSH) or working towards chartership
Strong understanding of CDM, temporary works, excavation safety, environmental interaction, and high-risk operations typical of enabling works
Excellent communication skills with the ability to influence at all levels
Strategic thinker with confidence to challenge, lead change, and implement best practice

Job Responsibility

Set the strategic direction for all health, safety, and wellbeing activities across the company
Ensure the business maintains the highest standards of compliance, promotes a proactive safety culture, and continuously improves its systems and behaviours

Fulltime

Director of Safety EPC

As the primary leader and manager of the Company’s safety initiatives, the LCM D...

Location

United States , Calvert

Salary:

Not provided

Lexicon, Inc

Expiration Date

Until further notice

Requirements

Bachelor’s degree in industrial Hygiene, Safety Management, Environmental Science, Occupational Health, or a related field
Minimum of 10 years of progressive safety leadership experience in the industrial construction or EPC industry
Professional certifications such as Certified Safety Professional (CSP) or Construction Health and Safety Technician (CHST) preferred
Comprehensive knowledge of OSHA, DOSH, ANSI, NFPA, EPA, and other relevant safety and environmental regulations
Strong understanding of workers’ compensation and claims management processes
Proficient in safety management systems and technologies including Procore, Power BI, Microsoft Word, Excel, and Outlook
Experience with EPC construction operations and subcontractor oversight
Must be legally authorized to work in the United States for our company without the need for current or future visa sponsorship
Ability to travel up to 50% of the time based on project and operational needs
Must be capable of wearing required personal protective equipment (PPE)

Job Responsibility

Lead the development, communication, and implementation of the Company’s safety vision, objectives, strategies, policies, and procedures
Provide proactive leadership by anticipating potential safety risks, identifying solutions, and fostering a culture of accountability, trust, and continuous improvement
Mentor, train, and empower safety professionals, field teams, and management to promote ownership of safety performance
Serve as a visible and approachable leader who models safety excellence
Oversee all safety operations for the LCM Division, ensuring consistency and effectiveness of safety initiatives across EPC projects
Manage and evaluate subcontractor safety programs, ensuring compliance with Company standards, client expectations, and all regulatory requirements
Lead and support Field Safety Managers in ensuring job sites remain hazard-free through periodic safety audits and inspections
Direct the development and maintenance of the Site-Specific Safety Plan (SSSP) process
Serve as the primary liaison for all external safety and risk management agencies, including OSHA and other federal, state, and local authorities
Oversee incident investigations and ensure thorough root cause analysis and corrective action follow-up

What we offer

Health, Dental, Vision, and Life Insurance
HSA with employer contributions
Life Insurance
Paid Holidays and Vacation
401k with company match
Lexicon University provides free career development and training

Fulltime

Director of Safety and Quality

Merlin is a venture backed aerospace startup building a non-human pilot to enabl...

Location

United States

Salary:

Not provided

Merlin Labs

Expiration Date

Until further notice

Requirements

10+ years of experience leading complex safety, regulatory, and compliance projects in a technology company, startup, or government agency
Proven ability to build relationships with senior leaders in government, industry, and academia
Strong organizational skills with exceptional attention to detail
Ability to remain calm and decisive in high-pressure situations
Capable of working independently and collaboratively within a team

Job Responsibility

Leadership and Strategy: Report to the CEO, overseeing the development and execution of short- and long-term safety and regulatory strategies, plans, and resources
SMS and QMS Leadership: Lead the integration and continuous improvement of Safety Management Systems and Quality Management Systems across the entire business, ensuring compliance with international standards and regulations
Cross-Functional Collaboration: Work closely with certification, compliance, regulatory, and engineering teams on technology projects, and manage the program management process for obtaining approvals for autonomous technology from global regulatory agencies such as FAA, NASA, Department of Transportation, Department of Defense, ICAO, and EASA
Consultant Management: Coordinate with a roster of external consultants and experts to ensure their seamless integration into Merlin's programs, maximizing their impact as force multipliers
Program and Project Management: Oversee the selection and administration of project tracking tools, optimizing program management across global policy, compliance, safety, and regulatory affairs teams
Team Development and Standards: Foster a culture of excellence by developing work standards and guidelines for the team, ensuring adherence to established procedures, processes, and compliance standards
Relationship Building: Identify, track, and manage critical regulatory, policy, and industry relationships both domestically and internationally, in collaboration with business development and company leads

What we offer

health
dental
life
unlimited vacation
401k with match

Fulltime

Senior Director of Product Management

The goTenna Product team is seeking a highly professional and experienced Produc...

Location

Salary:

175000.00 - 220000.00 USD / Year

goTenna

Expiration Date

Until further notice

Requirements

6+ years of experience working as Director of Product Management, Product Lifecycle Manager or Product Portfolio Manager in a technical product field - preferably in the telecoms, LMR radio or satellite systems segments
4+ years of experience with Agile methodologies for Software Development (including use of Jira & Confluence)
3+ years of experience with Waterfall/Stage-Gate methodologies for Hardware Development processes
Demonstrated experience managing business initiatives involving a portfolio of products in various lifecycle stages
Experience conducting market research, technical research and competitive analysis
Professional Communication skills: project specifications, documentation and presentations
Experience directly managing Product Managers and/or Product Owners
ITAR: U.S. Citizen or Green Card Required

Job Responsibility

Strategic Product Leadership: The Senior Director of Product Management is the key owner of an assigned product or product portfolio
Portfolio Strategy: Working in conjunction with the VP of Product and key internal and external stakeholders, the Product Manager shall define and communicate a compelling, long-term product strategy that aligns with market opportunities, customer needs and overall business objectives
Market & Competitive Analysis: Conduct deep market research, including regular interaction with current lighthouse customers, target market customers, industry experts, and sales channels
Business Case Development: Develop and maintain robust business cases for new product investments, justifying resource allocation, forecasting financial returns (ROI), and defining success metrics
Go-to-Market Strategy: Partner with Marketing, Sales, and Business Development to define and execute effective go-to-market plans for product launches
Customer & Stakeholder Empathy: Serve as the primary voice of the customer, translating complex operational requirements from critical communications end-users into actionable product requirements
Roadmap Management: Own, prioritize, and maintain the product roadmap for the product or product portfolio
Requirements Definition: Create clear, concise, and prioritized Product Requirements Documents (PRDs), translating those requirements into initiatives and feature epics
Feature Prioritization: Use data-driven decisions, product strategic goals, and market feedback to make tough, objective decisions on feature trade-offs and backlog prioritization
Lifecycle Management: Manage products across their entire lifecycle, including defining end-of-life strategies and transition plans for legacy systems

What we offer

Equity
401(k) plan
Unlimited PTO
Parental Leave with Pay
Holiday pay (including December recess)
Medical, Dental, Vision and life insurance
Pre-tax benefits
Short- and Long-term disability plans
Professional Development Stipend

Fulltime

Senior Director of Product (Head of International - Real Time Operations)

As Head of International – Real Time Operations, you will own the strategy and e...

Location

United Kingdom , London

Salary:

Not provided

Axon

Expiration Date

Until further notice

Requirements

10+ years of product management experience in enterprise SaaS, real-time operations, VSaaS, VMS, IoT, or public safety technology
Proven success in international product leadership, including experience scaling platforms across multiple regions with diverse compliance and operational requirements
Experience partnering with sales leadership on tender-driven opportunities, translating deal pipelines into prioritized product roadmaps
Strong understanding of global compliance standards (privacy, data residency, security) and their impact on product delivery
Demonstrated ability to harmonize requirements across geographies while balancing global parity vs. regional differentiation
Excellent communication and collaboration skills
able to influence senior leaders and cross-functional teams without direct authority
Bachelor’s degree required
MBA or advanced degree preferred

Job Responsibility

Define the international product strategy for Fusus, balancing competitiveness, sustainability, and scalability
Partner directly with international sales leadership to evaluate pipeline opportunities, shape tender responses, and prioritize engineering work to win deals
Harmonize requirements across countries and regions, ensuring strategic parity with U.S. markets where necessary, while building features and capabilities that truly matter for international success
Collaborate with product, engineering, and program leaders to ensure international deliverables are embedded in Axon’s global roadmap
Ensure compliance with regional security, privacy, and data residency standards critical to customer trust and adoption
Drive continuous improvement in tender readiness, adoption, and customer success metrics across regions
Act as a champion for international customer and partner needs within RTO, ensuring they inform product priorities at all stages
Build strong partnerships across Axon (devices, digital evidence, productivity solutions) to deliver integrated outcomes internationally
Lead direct engagement with international customers, regulators, and partners to distill insights into product priorities
Establish a clear execution path within 90 days that defines roadmap priorities and sequencing for international expansion

What we offer

Competitive base salary and RSUs
Comprehensive pension plan with matching contribution
Private health insurance & cash plans
30 days paid holiday + UK public holidays
Enhanced maternity/paternity leave
GymPass subscription
Life assurance & income protection
Career growth support and wellness resources

Fulltime

Senior Medical Director, Clinical Development

Cabaletta is seeking an experienced, highly motivated hands-on physician leader ...

Location

United States , Philadelphia

Salary:

Not provided

Cabaletta Bio Inc

Expiration Date

Until further notice

Requirements

D., M.D./Ph.D. degree or equivalent required
Board Certification, Board Eligibility, or clinical experience in the field of Rheumatology and/or Immunology highly desirable
7+ years of experience in clinical research, including the design and execution of complex clinical trials, with a pharmaceutical or biotech company
Experience with or exposure to the development of adoptive cell therapies or biologic therapies is desirable
Experience with Health Authority interactions and submission of clinical regulatory documents is desirable
Strong written and verbal communication skills
ability to easily engage with investigators and key external experts
and ability to effectively present at conferences, advisory meetings, and other public for a
Engaged, hands-on, independent, and goal-oriented mentality
willingness to work in highly dynamic work environment

Job Responsibility

Provide medical leadership for various programs from first-in-human studies through registrational studies
Formulate study designs, lead protocol development, partner with internal cross-functional teams in study start-up activities, and collaborate with clinical investigators, key external experts, and Health Authorities
Participate in direct, hands-on involvement in all aspects of study conduct clinical activities, working with clinical operations, including data review, analysis, and reporting that conform to the ethical, safety, and quality standards of Cabaletta, GCP, and Health Authorities
Become an expert and remain current in the relevant therapeutic areas and in the field of cell and gene therapy through review of the scientific literature, interactions with key external experts, and attendance at relevant scientific meetings
Actively contribute during Health Authority interactions
Review available preclinical data that could inform the design of future clinical trials
Present at site evaluation and site initiation visits as applicable
In partnership with relevant cross-functional team members, actively engage in the preparation of Clinical Study Reports, Annual Reports and other safety reports, Health Authority pre-meeting packages, Investigator Brochures, periodic clinical reports, and BLA submission documents
Collaborating with cross-functional groups, formulate publication strategy including active participation in authoring, preparation and review of manuscripts, conference abstracts and presentations and other external presentations of clinical data

What we offer

health and retirement, PTO, and stock option plans

Senior Director Public Health

The Senior Director, Public Health provides scientific and strategic leadership ...

Location

United States , Washington, DC

Salary:

150000.00 - 165000.00 USD / Year

American Cleaning Institute

Expiration Date

Until further notice

Requirements

Master’s degree required or Doctorate preferred, in public health, or a related field
Minimum 5 years of experience in scientific research management, regulatory science, or related public health programs
experience with FDA-regulated products strongly preferred
Demonstrated experience managing multi-stakeholder research programs or clinical studies under FDA frameworks
Comprehensive understanding of FDA rules and regulations, topical antiseptic safety and efficacy requirements, and relevant regulatory guidance
Excellent scientific writing and communication skills, including experience preparing manuscripts, white papers, and regulatory submissions
Exceptional oral and written communication skills
Ability to interact productively with both internal and external stakeholders, including non-scientific audiences
Proven ability to manage contractors, academic partners, and collaborations on scientific projects
Ability to work within a team environment as well as independently

Job Responsibility

Lead and oversee ACI’s Topical Antiseptics Program, including clinical and technical research supporting the FDA OTC Monographs and related scientific priorities
Keep abreast of emerging science and regulatory policies, monitor technical literature, and write and review technical reports, white papers, and publications for peer-reviewed scientific journals
Direct design, execution, and analysis of studies assessing product safety, efficacy, and antimicrobial benefits. Ensure compliance with regulatory and scientific standards
Serve as the primary scientific liaison to FDA and other regulatory bodies on antiseptic-related topics
interpret and communicate evolving regulatory expectations to ACI leadership and members
Coordinate and facilitate scientific work groups, technical committees, and member coalitions advancing antiseptic science
Prepare status/progress reports for presentation to ACI’s leadership and members
Develop and administer program budgets and deliverables
oversee contracts, research partnerships and consultant engagement
Develop and deliver scientific messaging for external stakeholders such as at scientific and technical conferences and meetings, and audiences for ACI technical communications

Senior Director, Safety

Crusoe

Location:
United States , San Francisco

Category:
IT - Administration

Contract Type:
Not provided

Salary:

Job Description:

Job Responsibility:

Requirements:

Nice to have:

Additional Information:

Job Posted:
February 21, 2026

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