Senior Director, Manufacturing, Science & Technology Job at Theramex (London)

Senior Director, Analytical Development and Quality Control

The Altos Institute of Medicine will capture knowledge generated about cell heal...

Location

United States , Redwood City

Salary:

283900.00 - 384100.00 USD / Year

Altos Labs

Expiration Date

Until further notice

Requirements

Ph.D. in analytical sciences or biological sciences
Minimum 15+ years of analytical development and QC experience in biotech/pharmaceutical industry
10+ years of Management experience
Highly experienced in developing and implementing assays for Quality Control testing and characterization of drug substance, drug product and manufacturing in-process samples
Experienced in multiple modalities including biologics, oligonucleotides, small molecules, mRNA/LNP and AAV gene therapy
Experienced in leading CMC team and analytical subteam
Proficient in cGMP’s and pharmaceutical industry procedures and regulations
Highly experienced in achieving CMC deliverables through outsourcing to Contract Manufacturing Organizations
Leadership experience in managing diverse project activities with contract CDMO facilities at global locations
A critical thinker with the ability to analyze possibilities and solutions and make pragmatic trade-offs

Job Responsibility

Lead analytical development and quality control across multiple modalities
Build a high performing team and establish internal and external analytical and QC capabilities
Serve as CMC lead and analytical lead for Altos therapeutic programs
Manage contract manufacturing organizations and CROs to develop and qualify analytical testing methods, perform product characterization, release and stability testing, and in-process testing
Establish product specifications to ensure product quality
Support technical assessment of Out of Specification and Non-Conforming investigations
Author, review, and/or approve Standard Operating Procedures, specifications, regulatory filing, or other controlled documents
As a member of the Tech Ops leadership team, build the Tech Ops organization, processes, systems and infrastructure
Create and foster strong partnerships with Institutes of Science, Institutes of Technology, Institute of Computation, drug discovery and development sciences, clinical, regulatory, program management, business development, legal and finance
Actively contribute to a team culture that promotes continuous improvement, accountability, professional growth, and inclusion

Fulltime

New

Test and Evaluation Engineer

At Boeing, we innovate and collaborate to make the world a better place. We’re c...

Location

United States , Huntsville; John F Kennedy Space Center; Titusville; John C Stennis Space Center; New Orleans

Salary:

112200.00 - 163300.00 USD / Year

Boeing

Expiration Date

January 30, 2026

Requirements

Bachelor of Science degree in Engineering, Engineering Technology (including Manufacturing Technology), Computer Science, Data Science, Mathematics, Physics, Chemistry or non-US equivalent qualifications directly related to the work statement
7+ years of experience in complex test planning, development, and execution
3+ years of experience working directly on vehicles with Cryogenic Propulsion Systems (RS-68, SSME, RS-25, RL-10, J-2X, RD-180, etc)
Experience with system level testing of flight vehicle main propulsion, thrust vector control, and avionics systems
Experience interfacing with senior and executive leadership
Engineering related experience interfacing with customers
Willing to travel domestically as needed
Ability to obtain access to a National Aeronautics and Space Administration (NASA) facility
U.S. Person as defined by 22 C.F.R. §120.62 required

Job Responsibility

Acts as the Deputy Test Director for the EUS Wet Dress Rehearsal and Hot Fire test to be performed at Stennis Space Center, MS – Temporary Assignment required if based in AL or FL
Leads a multifunction team of test engineers and Subject Matter Experts (SME)
Develops and documents standardized test methods and processes to ensure repeatability and productivity
Leads the development of test procedures to incorporate vehicle and system maturity updates while ensuring test maintenance requirements and verification objectives are met
Applies lessons learned to the improvement of test procedures
Guides others in the design of test hardware, software and systems to achieve the test requirements
Oversees debriefing of the test team
Leads the analysis, processing and formatting of data to customer requirements
Approves test data prior to delivery to customer
Formulates expectations for test data based on historical data

What we offer

Competitive base pay and variable compensation opportunities
Health insurance
Flexible spending accounts
Health savings accounts
Retirement savings plans
Life and disability insurance programs
Paid and unpaid time away from work
Generous company match to your 401(k)
Industry-leading tuition assistance program
Fertility, adoption, and surrogacy benefits

Fulltime

!

Senior Director, Drug Substance Development and Manufacturing (Peptide)

We are seeking an accomplished and strategic Senior Director, Drug Substance Dev...

Location

United States , Waltham

Salary:

210000.00 - 270000.00 USD / Year

Kailera Therapeutics

Expiration Date

Until further notice

Requirements

Minimum of 10+ years of progressive, relevant experience in drug substance development and manufacturing
Deep expertise in both synthetic and recombinant manufacturing approaches
Hands-on experience with the synthesis and manufacturing of peptides is mandatory
Demonstrated track record in managing clinical-scale supply, process characterization and optimization, technical transfers, and process validation activities
Sound technical skills in applying scientific principles to complex process design, implementation, and successful technology transfer
Solid knowledge of current Good Manufacturing Practices (cGMPs), Quality systems, and global regulatory requirements (e.g., FDA, EMA)
Proven experience with the drafting, review, and authoring of CMC sections for major global regulatory submissions (e.g., IND, NDA, MAA)
Exceptional solution-based critical thinking skills and the ability to operate with a keen sense of urgency and an entrepreneurial spirit
Demonstrated ability to ensure accountability of self and others, coupled with strong detail-orientation
Ability to strategically contribute to and manage multiple concurrent projects

Job Responsibility

Direct and lead all process development, scale-up, technology transfer, and validation activities for peptide drug substance manufacturing across all Contract Development and Manufacturing Organizations (CDMOs)
Establish and drive continuous improvement initiatives focused on enhancing manufacturing efficiency, enabling cost reduction, and establishing strategic redundancies across the CDMO network
Define the long-term vision for manufacturing by maintaining a deep knowledge of industry trends, technological advancements, green manufacturing processes, and emerging regulatory changes
Manage and enforce CDMO performance against key project timelines, deliverables, and costs
Lead the negotiation and execution of complex technical agreements and work orders with CDMO partners
Oversee budget planning and forecasting for all outsourced drug substance manufacturing activities
Serve as the strategic lead for drug substance activities, driving seamless collaboration across Analytical Development, Formulation, Quality Assurance, and Regulatory Affairs
Oversee the preparation and completion of drug substance modules (e.g., Module 3) for all regulatory dossiers (e.g., IND, NDA)
Direct the preparation and final authorship of high-quality technical reports, executive summaries, and presentations to effectively communicate results and progress to internal leadership and external stakeholders

What we offer

Comprehensive health coverage
Flexible time off
Paid holidays
Year-end shutdown
Monthly wellness stipend
Generous 401(k) match
Tuition reimbursement
Commuter benefits
Disability and life insurance
Annual bonus opportunities

Fulltime

New

Sales Director / Senior Account Executive

Userlane helps enterprises understand and improve the value of their software. W...

Location

United States of America

Salary:

Not provided

Userlane GmbH

Expiration Date

Until further notice

Requirements

5+ years of enterprise software sales experience in regulated industries - healthcare, life sciences, or manufacturing required
Proven track record of closing $250K+ ACV deals with multiple stakeholders and long sales cycles
Deep understanding of how regulated organizations buy, implement, and govern technology
Strong experience working within a partner ecosystem: co-selling, channel enablement, joint account planning
Comfortable explaining technical concepts (APIs, SSO, data governance) without being a technical seller
Consultative approach: you lead with insight, not features
Excellent at building relationships with C-suite, IT, and operational leaders
Self-starter mentality with a track record of exceeding quota
Experience with value-based or ROI-driven selling preferred
Familiarity with Digital Adoption Platforms, Change Enablement, or enterprise analytics tools a plus

Job Responsibility

Own and drive $1M+ ARR quota through new logo acquisition and expansion in enterprise accounts
Build and execute account strategies for complex, multi-stakeholder organizations in healthcare, life sciences, or manufacturing
Navigate regulatory and compliance requirements that shape buying processes in these industries
Develop and support strategic partnerships with Vendors, system integrators, and technology consultancies
Lead complex sales cycles involving software integration, data security reviews, and procurement processes
Articulate the business case for software optimization, waste reduction, and adoption intelligence - especially around major system deployments (Epic, Cerner, Oracle, SAP, etc.)
Collaborate with Solution Consultants to scope technical requirements and demonstrate value
Forecast accurately and manage pipeline with discipline
Act as the voice of the customer, feeding insights back to Product and Marketing

What we offer

Competitive base salary + uncapped commission plan with accelerators
Team & Culture: A high-performance culture with great leadership and a fun, engaged, motivated and diverse team with people from over 20 countries
Impact: You’ll be part of an empowered cross-functional team given the freedom and autonomy to solve real customer problems
Sales strategy influence: Work directly with our VP Sales to shape our 2026-2030 strategy as we expand into new sectors
Market: Userlane is among the global leaders in the rapidly growing Digital Adoption industry
Growth: We take you and your development seriously. You can expect weekly 121s, a personalised skills assessment and development plan, on-the-job coaching and budget for events and training

Fulltime

General manager

As the Divisional President/General Manager, you will be responsible for the ful...

Location

China , Shanghai

Salary:

1300000.00 - 1700000.00 CNY / Year

Randstad

Expiration Date

March 18, 2026

Requirements

Bachelor of Science in Business and/or Engineering is required
MBA is preferred
Proven experience in a senior leadership role within a manufacturing company
At least 10+ years of business management responsibility within a similar market or industry
Demonstrated ability to plan, organize, and control operating units, specifically in creating and executing multi-year business and budget plans
Ability to meet specific cognitive and mechanical benchmarks
Must demonstrate the 'Characteristics of a Successful Manager' and a commitment to continuous improvement and high-quality standards

Job Responsibility

Establishing the operating unit's strategic statements and culture of excellence in alignment with the Global Vision
Developing and implementing comprehensive three-year business plans, including detailed annual operating plans and budgets
Directing day-to-day operations to ensure effective customer experiences, business growth, and operational efficiency
Managing the development of personnel, product technology, equipment, and market resources to facilitate future expansion
Ensuring 100% on-time performance reviews and corrective action responses to maintain high standards of employee relations and customer satisfaction
Providing transparent communication through monthly reports to the CEO and quarterly reports to the Board of Directors

New

Director/senior director, program management

As an experienced Program Manager, you will play a critical role in achieving ou...

Location

United States , Cambridge

Salary:

210000.00 - 320000.00 USD / Year

Beam Therapeutics

Expiration Date

Until further notice

Requirements

12+ years of experience in the life sciences industry
at least 5 years of demonstrated program management experience leading cross-functional teams in biotechnology
BS required
preference for candidates holding an advanced degree (MS, PhD, MBA, etc.)
experience driving cell and/or gene therapy programs is strongly preferred
candidates must live locally and be able to visit our Cambridge location 1–3 days per week as needed
proven ability to manage competing priorities, influence and integrate diverse teams, identify barriers, and manage budgets, timelines, and meeting plans
demonstrated strategic leadership skills, including the ability to influence senior stakeholders and drive decision-making in complex, matrixed environments
experience managing multiple programs or contributing to portfolio strategy and governance
expertise in risk management, scenario planning, and contingency development

Job Responsibility

Overall accountability for program operations
drive the BEAM-302 program team by partnering closely with the Program Lead and cross-functional program team members to manage all operational aspects of the program
lead and operationalize program activities across manufacturing, clinical development, CMC, regulatory, and other cross-functional teams to ensure seamless integration and alignment with BEAM-302 objectives
manage and integrate program plans and cross-functional deliverables (e.g., timelines, budgets, resource allocation, identification of risks and barriers, identification of mitigation plans, development of scenarios, and integration of key documents like TPPs and IDPs)
ensure cross-functional alignment and organizational support for the program plan by facilitating internal and external stakeholder management, as well as communicating program updates at internal forums
provide strategic input into program objectives and ensure alignment with corporate goals
drive scenario planning and trade-off discussions to enable informed decision-making at governance forums
establish proactive risk management frameworks and ensure timely escalation of critical issues
develop contingency plans for high-impact risks and communicate mitigation strategies to leadership
drive cross-functional initiatives that support operational excellence

Fulltime

New

Executive Director, Global Planning

The Executive Director of Global Supply Chain Planning will lead the strategic, ...

Location

United States

Salary:

240000.00 - 360000.00 USD / Year

BioMarin Pharmaceutical

Expiration Date

Until further notice

Requirements

Bachelor’s degree in Supply Chain, Engineering, Life Sciences, or Business
15+ years of progressive experience in global supply chain planning
At least 5 years in a senior leadership role
Deep experience in biopharma supply chains, including clinical and commercial operations
Strong knowledge of GxP, regulatory compliance, and global operations
Proven experience with key technologies SAP ERP, SAP IBP, Kinaxis, O9, or OMP
Skilled in business process modeling tools (e.g., SIPOC, RACI) and scenario modeling
APICS or equivalent certification preferred
Advanced degree (MS, PhD, MBA) desired

Job Responsibility

Lead enterprise Integrated Business Planning (IBP) processes to align demand, supply, and financial goals
Oversee supply and demand planning, inventory optimization, production planning, and network planning across clinical and commercial portfolios
Drive forecasting and scenario planning to support strategic decision-making and risk mitigation
Ensure planning excellence across drug substance, drug product, and finished goods segmented supply chains
Champion the use of ERP and advanced planning tools (Kinaxis, O9, OMP) to enable real-time visibility and agility
Develop and execute a multi-year strategic roadmap for global planning transformation
Lead business process improvement initiatives using Lean, Six Sigma, Kaizen, and DMAIC methodologies
Establish and monitor KPIs to measure planning performance and supply chain resiliency
Leverage predictive analytics and data modeling to drive proactive planning
Partner with key stakeholders (Commercial, Development, Finance, Manufacturing, Quality, Regulatory, and IT)

What we offer

Discretionary annual bonus
Discretionary stock-based long-term incentives
Paid time off
Company-sponsored medical, dental, vision, and life insurance plans

Fulltime

Executive Director, Medicine Development Leader

GSK is seeking a highly skilled Executive Director, Medicine Development Leader ...

Location

United States; United Kingdom , Waltham; London; Stevenage; Collegeville

Salary:

242250.00 - 403750.00 USD / Year

GSK

Expiration Date

Until further notice

Requirements

Advanced degree including MD, PhD, PharmD, MBA, MS
Drug development expertise in the global pharmaceutical/biotechnology industry
Filing experience with BLA/NDA/MAA submissions as a core responsibility
Experience in the entirety of drug development across the R&D/commercial life cycle including Discovery, late-stage Development, Regulatory, Manufacturing Medical and Commercial
Experience in product development and/or commercialization, in late phase development (from clinical PoC onwards), clinical trial management, post-approval studies, regulatory and manufacturing compliance
Experience leading teams in a complex, matrixed, global and multi-disciplinary organization with high accountability, minimal authority and multiple lines of reporting
Experience working with regulators and with regulatory requirements including legal and government frameworks within and across global geographies
Experience creating the strategy for pre- and post-marketing studies and driving the lifecycle process
Experience building budgets and leading the strategic and budget planning process
Experience the healthcare environment, and access in all major markets

Job Responsibility

Act as a single point of accountability in GSK for all aspects of a medicine being developed globally, from proof of clinical activity (POC) to Approval in all major market(s)
Work closely with the Early Development Lead (EDL) and Medicine Commercial Lead (MCL) to ensure a smooth transition of the lead indication(s) from the EDL upon achievement of clinical PoC and to the MCL upon Approval in first major market(s)
Post-approval, provide key support to the Medicine Commercial Team (MCT) in the first major markets ensuring the MDT provides optimal support to registration, including Post-Marketing Requirements (PMRs) and life cycle management (LCM) in the major markets
Work with the functional line Heads supporting RIIRU to select MDT members and lead this multi-disciplinary matrix team, supporting differentiated development for team members, owning the performance of the MDT and partnering with Line Managers to drive performance
Partner with the Pipeline Project Manager (PPM), energize and motivate the MDT to drive a high performing team and operational delivery of the project, including setting team objectives to ensure successful project delivery, including options for acceleration, parallel indication development and smart risk-taking.
Partner with R&D Business Development, leading the development planning for a prospective in-licensed asset by bringing together input from the relevant functions and TA experts to develop a Medicine Profile (MP) and development plans including but not limited to clinical feasibility, regulatory planning and CMC risk mitigation
Leads the cross-functional MDT to: Establish a compelling vision for the medicine and Target Medicine Profile (TMP) which positions the medicine within the R&D strategy taking the competitive landscape into account, translating GSK’s strategy into asset strategy and actionable plans for multiple areas or functions
Deliver differentiated medicines of value for patients, stakeholders and markets through an evidence package that supports regulatory approval, market access and the product’s life cycle
Prioritize and maximize the asset’s development options including developing multiple indications
Partner with the Global Medical Lead (GML) and MCL to develop an indication expansion and LCM plan for the asset.

What we offer

Annual bonus
Eligibility to participate in our share based long term incentive program
Health care and other insurance benefits (for employee and family)
Retirement benefits
Paid holidays
Vacation
Paid caregiver/parental and medical leave

Fulltime

Senior Director, Manufacturing, Science & Technology

Theramex

Location:
United Kingdom , London

Category:
Manufacturing

Contract Type:
Not provided

Salary:

Job Description:

Job Responsibility:

Requirements:

Nice to have:

Additional Information:

Job Posted:
December 12, 2025

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