Senior Director, Manufacturing, Science & Technology Job at Theramex (London)

Senior Director, Analytical Development and Quality Control

The Altos Institute of Medicine will capture knowledge generated about cell heal...

Location

United States , Redwood City

Salary:

283900.00 - 384100.00 USD / Year

Altos Labs

Expiration Date

Until further notice

Requirements

Ph.D. in analytical sciences or biological sciences
Minimum 15+ years of analytical development and QC experience in biotech/pharmaceutical industry
10+ years of Management experience
Highly experienced in developing and implementing assays for Quality Control testing and characterization of drug substance, drug product and manufacturing in-process samples
Experienced in multiple modalities including biologics, oligonucleotides, small molecules, mRNA/LNP and AAV gene therapy
Experienced in leading CMC team and analytical subteam
Proficient in cGMP’s and pharmaceutical industry procedures and regulations
Highly experienced in achieving CMC deliverables through outsourcing to Contract Manufacturing Organizations
Leadership experience in managing diverse project activities with contract CDMO facilities at global locations
A critical thinker with the ability to analyze possibilities and solutions and make pragmatic trade-offs

Job Responsibility

Lead analytical development and quality control across multiple modalities
Build a high performing team and establish internal and external analytical and QC capabilities
Serve as CMC lead and analytical lead for Altos therapeutic programs
Manage contract manufacturing organizations and CROs to develop and qualify analytical testing methods, perform product characterization, release and stability testing, and in-process testing
Establish product specifications to ensure product quality
Support technical assessment of Out of Specification and Non-Conforming investigations
Author, review, and/or approve Standard Operating Procedures, specifications, regulatory filing, or other controlled documents
As a member of the Tech Ops leadership team, build the Tech Ops organization, processes, systems and infrastructure
Create and foster strong partnerships with Institutes of Science, Institutes of Technology, Institute of Computation, drug discovery and development sciences, clinical, regulatory, program management, business development, legal and finance
Actively contribute to a team culture that promotes continuous improvement, accountability, professional growth, and inclusion

Fulltime

Sr Director, MSAT

The Sr. Director, MSAT (Manufacturing Sciences, Analytics, and Technology) acts ...

Location

United States , Bedford

Salary:

Not provided

PCI Pharma Services

Expiration Date

Until further notice

Requirements

Bachelor’s degree in Life Sciences or equivalent experience required
Minimum of fifteen (15) years of relevant experience in cGMP manufacturing or equivalent
Proven experience leading innovation, managerial experience with extensive industry knowledge and an eye towards future technologies
Soft skills: Strategic thinking, adaptive thinking, and strong critical mindset. Strong business acumen and presentation skills. Excellent interpersonal, leadership, and communication skills. Impact & influence top leaders & external clients and regulators
Emphasis on aseptic processing and compliance required
Advanced-level verbal communication skills

Job Responsibility

Optimize the use of resources (human, fill finish equipment and support areas) across the organization in support of improving process robustness and forward-looking capabilities
Coordinates and supports cross functional teams with recommendations, advice, and action plans for complex investigations, change controls, gap analyses and risk assessments related to all manufacturing modalities
Oversees authoring and revision of compliance, change controls and other technical documentation to support critical MSAT changes
Assesses incoming client projects to ensure compatibility, compliance, and initial and ongoing profitability with AAI processes
Contributes advanced level support to internal and client audits when needed
Build and sustain common innovation roadmap between MSAT and Drug Product Manufacturing/Finishing to ensure continuum in innovation to accelerate client projects and sustainable process performance
Lead the client technical intake process team composed of engineers and specialists
Drive complex change management & anchor the changes in MSAT and with connected functions, Drug Product, Finishing, Quality Assurance and Quality Control
Responsible for exhibiting professional behavior with both internal and external business associates that reflect positively on the company and is consistent with the company’s policies and practices
Serves as key contact for clients during tech transfer and post manufacturing activities

Fulltime

Senior Director, Drug Substance Development and Manufacturing (Peptide)

We are seeking an accomplished and strategic Senior Director, Drug Substance Dev...

Location

United States , Waltham

Salary:

210000.00 - 270000.00 USD / Year

Kailera Therapeutics

Expiration Date

Until further notice

Requirements

Minimum of 10+ years of progressive, relevant experience in drug substance development and manufacturing
Deep expertise in both synthetic and recombinant manufacturing approaches
Hands-on experience with the synthesis and manufacturing of peptides is mandatory
Demonstrated track record in managing clinical-scale supply, process characterization and optimization, technical transfers, and process validation activities
Sound technical skills in applying scientific principles to complex process design, implementation, and successful technology transfer
Solid knowledge of current Good Manufacturing Practices (cGMPs), Quality systems, and global regulatory requirements (e.g., FDA, EMA)
Proven experience with the drafting, review, and authoring of CMC sections for major global regulatory submissions (e.g., IND, NDA, MAA)
Exceptional solution-based critical thinking skills and the ability to operate with a keen sense of urgency and an entrepreneurial spirit
Demonstrated ability to ensure accountability of self and others, coupled with strong detail-orientation
Ability to strategically contribute to and manage multiple concurrent projects

Job Responsibility

Direct and lead all process development, scale-up, technology transfer, and validation activities for peptide drug substance manufacturing across all Contract Development and Manufacturing Organizations (CDMOs)
Establish and drive continuous improvement initiatives focused on enhancing manufacturing efficiency, enabling cost reduction, and establishing strategic redundancies across the CDMO network
Define the long-term vision for manufacturing by maintaining a deep knowledge of industry trends, technological advancements, green manufacturing processes, and emerging regulatory changes
Manage and enforce CDMO performance against key project timelines, deliverables, and costs
Lead the negotiation and execution of complex technical agreements and work orders with CDMO partners
Oversee budget planning and forecasting for all outsourced drug substance manufacturing activities
Serve as the strategic lead for drug substance activities, driving seamless collaboration across Analytical Development, Formulation, Quality Assurance, and Regulatory Affairs
Oversee the preparation and completion of drug substance modules (e.g., Module 3) for all regulatory dossiers (e.g., IND, NDA)
Direct the preparation and final authorship of high-quality technical reports, executive summaries, and presentations to effectively communicate results and progress to internal leadership and external stakeholders

What we offer

Comprehensive health coverage
Flexible time off
Paid holidays
Year-end shutdown
Monthly wellness stipend
Generous 401(k) match
Tuition reimbursement
Commuter benefits
Disability and life insurance
Annual bonus opportunities

Fulltime

Director, IT Systems

The Head of IT will be responsible for the overall strategy, development, and op...

Location

United States , Garden Grove

Salary:

140000.00 - 180000.00 USD / Year

Harbinger Motors

Expiration Date

Until further notice

Requirements

Bachelor's degree in Computer Science, Information Technology, Engineering, or a related field. Master's degree preferred
Minimum of 12+ years of progressive experience in Information Technology, with at least 3 years in a senior leadership role (e.g., Head of IT, IT Director)
Proven experience in a manufacturing, automotive, or high-growth technology company is essential. EV experience is a significant plus
Strong knowledge of cybersecurity best practices, compliance, and risk management
Exceptional leadership, communication, and interpersonal skills, with the ability to translate technical concepts for a non-technical audience

Job Responsibility

Develop and execute a comprehensive, scalable IT roadmap that aligns with the company's business goals
Serve as the key technology leader and strategic advisor to the executive team
Manage the annual IT budget
Build, mentor, and lead a high-performing IT team
Manage and maintain the entire IT infrastructure, including cloud services, data centers, networks, and end-user hardware/software
Establish and enforce a robust cybersecurity framework
Develop and manage comprehensive Disaster Recovery and Business Continuity plans
Collaborate with Product and Engineering teams to support the data pipeline for vehicle telematics, charging network data, and fleet management systems
Establish secure and efficient data warehousing/lake solutions

What we offer

Comprehensive Health, Dental & Vision (HDV) – 100% employee covered
Early-stage Stock Options
Robust Retirement Savings (401k, HSA, FSA)
Generous Paid Time Off (PTO) & Parental Leave
Annual Vacation Bonus
Wellness & Fertility Benefits
Cell Phone Stipend
Complimentary Meals & Stocked Kitchens

Fulltime

Sales Director / Senior Account Executive

Userlane helps enterprises understand and improve the value of their software. W...

Location

United States of America

Salary:

Not provided

Userlane GmbH

Expiration Date

Until further notice

Requirements

5+ years of enterprise software sales experience in regulated industries - healthcare, life sciences, or manufacturing required
Proven track record of closing $250K+ ACV deals with multiple stakeholders and long sales cycles
Deep understanding of how regulated organizations buy, implement, and govern technology
Strong experience working within a partner ecosystem: co-selling, channel enablement, joint account planning
Comfortable explaining technical concepts (APIs, SSO, data governance) without being a technical seller
Consultative approach: you lead with insight, not features
Excellent at building relationships with C-suite, IT, and operational leaders
Self-starter mentality with a track record of exceeding quota
Experience with value-based or ROI-driven selling preferred
Familiarity with Digital Adoption Platforms, Change Enablement, or enterprise analytics tools a plus

Job Responsibility

Own and drive $1M+ ARR quota through new logo acquisition and expansion in enterprise accounts
Build and execute account strategies for complex, multi-stakeholder organizations in healthcare, life sciences, or manufacturing
Navigate regulatory and compliance requirements that shape buying processes in these industries
Develop and support strategic partnerships with Vendors, system integrators, and technology consultancies
Lead complex sales cycles involving software integration, data security reviews, and procurement processes
Articulate the business case for software optimization, waste reduction, and adoption intelligence - especially around major system deployments (Epic, Cerner, Oracle, SAP, etc.)
Collaborate with Solution Consultants to scope technical requirements and demonstrate value
Forecast accurately and manage pipeline with discipline
Act as the voice of the customer, feeding insights back to Product and Marketing

What we offer

Competitive base salary + uncapped commission plan with accelerators
Team & Culture: A high-performance culture with great leadership and a fun, engaged, motivated and diverse team with people from over 20 countries
Impact: You’ll be part of an empowered cross-functional team given the freedom and autonomy to solve real customer problems
Sales strategy influence: Work directly with our VP Sales to shape our 2026-2030 strategy as we expand into new sectors
Market: Userlane is among the global leaders in the rapidly growing Digital Adoption industry
Growth: We take you and your development seriously. You can expect weekly 121s, a personalised skills assessment and development plan, on-the-job coaching and budget for events and training

Fulltime

Digital Solutions Architect Senior Director

We are seeking a Manufacturing & Supply Chain Domain Architect with deep experie...

Location

United States , Los Angeles

Salary:

Not provided

NTT DATA

Expiration Date

Until further notice

Requirements

10+ years in Manufacturing or Supply Chain, ideally with domain architecture or process transformation experience
Deep understanding of manufacturing and logistics operations, including production lifecycle, procurement, inventory, planning, order management, and quality/process control
Demonstrated experience designing target operating models or orchestrating digital transformation in manufacturing or supply chain environments
Strong understanding of automation strategies, digital supply chain, Industry 4.0 technologies, and BPaaS models
Familiarity with AI/ML concepts, LLMs, agent orchestration, or predictive analytics (even if not hands-on)
Strong client-facing communication skills, with the ability to simplify complexity and influence senior executives
Ability to work across multifunctional teams including engineering, product, data science, and operations leadership

Job Responsibility

Lead domain architecture for Manufacturing Operations, Supply Chain Planning, Procurement, Logistics, Distribution, and Aftermarket Services
Architect future-state processes using AI agents across areas such as: Production planning and scheduling, Inventory optimization, Supplier management & procurement orchestration, Quality management & defect intelligence, Warehouse & transportation operations, Shop-floor automation and digital work instructions
Translate domain regulations, safety constraints, and operational requirements into scalable AI-driven workflows
Design modular BPS/BPaaS solutions leveraging agentic platforms, autonomous planning engines, and decision-support systems
Collaborate with ontology, ML, and engineering teams to define data models, event structures, and operational ontologies for manufacturing and supply chain use cases
Create reusable domain patterns and accelerators for faster transformation across industrial clients
Conduct deep discovery of client operations, supply chain flows, plant processes, and manufacturing KPIs
Present architectural designs, transformation plans, and AI-driven value cases to C-level leaders, including COOs, CSCOs, and Heads of Manufacturing
Guide clients through AI-native adoption, including change management, operational governance, and automation strategy
Align industry priorities—resiliency, cost efficiency, sustainability—with platform capabilities and transformation roadmaps

Fulltime

General manager

As the Divisional President/General Manager, you will be responsible for the ful...

Location

China , Shanghai

Salary:

1300000.00 - 1700000.00 CNY / Year

Randstad

Expiration Date

March 18, 2026

Requirements

Bachelor of Science in Business and/or Engineering is required
MBA is preferred
Proven experience in a senior leadership role within a manufacturing company
At least 10+ years of business management responsibility within a similar market or industry
Demonstrated ability to plan, organize, and control operating units, specifically in creating and executing multi-year business and budget plans
Ability to meet specific cognitive and mechanical benchmarks
Must demonstrate the 'Characteristics of a Successful Manager' and a commitment to continuous improvement and high-quality standards

Job Responsibility

Establishing the operating unit's strategic statements and culture of excellence in alignment with the Global Vision
Developing and implementing comprehensive three-year business plans, including detailed annual operating plans and budgets
Directing day-to-day operations to ensure effective customer experiences, business growth, and operational efficiency
Managing the development of personnel, product technology, equipment, and market resources to facilitate future expansion
Ensuring 100% on-time performance reviews and corrective action responses to maintain high standards of employee relations and customer satisfaction
Providing transparent communication through monthly reports to the CEO and quarterly reports to the Board of Directors

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Director, Solution Architecture

Global Technology Solutions (GTS) at ResMed is a division dedicated to creating ...

Location

Australia , Sydney

Salary:

Not provided

ResMed

Expiration Date

Until further notice

Requirements

15+ years in enterprise / solution architecture
8+ years leading architecture for large-scale ERP or global transformation programs
Hands-on experience with Oracle Fusion Cloud ERP (preferred) or similar Tier-1 SaaS ERP (SAP S/4HANA, Workday, etc.), covering at least two of: Finance, Supply Chain, Manufacturing, Commercial
Proven track record designing and implementing target-state architectures for global organizations (multi-region, multi-entity, multi-currency)
Deep understanding of enterprise systems integration and data architecture – APIs, services, event-driven patterns, batch, and master data domains
Strong experience with cloud platforms (e.g., Azure, AWS, or Oracle Cloud Infrastructure) and modern integration platforms (iPaaS, ESB, API gateways)
Demonstrated ability to lead and develop teams of architects or technical leads across domains and/or vendors (direct or matrix)
Proven success driving architectural decisions, setting standards, and enforcing adherence across programs and partners
Solid knowledge of regulatory and compliance frameworks relevant to ERP and data (e.g., SOX, GDPR, ISO13485), with experience embedding these into solution design
High fluency with architecture methods and modeling (e.g., TOGAF, ArchiMate or similar) and documenting decisions through clear, consumable artifacts

Job Responsibility

Define the target-state architecture and drive design decisions to ensure alignment with enterprise architecture principles, program objectives, and global business requirements
Runs the design authority for the ERP transformation program, enabling key solution designs and resolving trade-offs between cost, speed, risk, and compliance
Lead the Solution Architecture chapter, setting standards, coaching architects, managing performance, and building capability across domains and programs
Own the cross-domain integration strategy between Oracle Fusion ERP and third-party applications, ensuring scalable, secure, and resilient data flows and interoperability
Embed governance and compliance into solution design by partnering with data, security, and regulatory teams to meet SOX, GDPR, ISO13485 and other relevant standards
Collaborate closely with Enterprise Architecture, Application, and Program leadership to co-create the multi-year architecture roadmap and ensure technology choices support long-term business strategy
Lead architecture review forums and communities of practice, ensuring consistent application of patterns, principles, and reference architectures across vendors and workstreams
Direct and challenge system integration partners and vendors, ensuring proposed solutions align with Resmed’s reference architecture, are fit-for-purpose, and avoid unnecessary complexity and duplication
Identify architecture risks and constraints early and drive mitigation plans in partnership with program leadership and domain teams
Communicate architecture decisions and their business impact clearly to senior stakeholders, translating complex technical topics into concise options and recommendations

What we offer

Challenging, supportive and inspiring career
Culture driven by excellence
Focus on creating a diverse and inclusive culture, encouraging individual expression in the workplace
Thrive on innovative ideas

Fulltime

Senior Director, Manufacturing, Science & Technology

Theramex

Location:
United Kingdom , London

Category:
Manufacturing

Contract Type:
Not provided

Salary:

Job Description:

Job Responsibility:

Requirements:

Nice to have:

Additional Information:

Job Posted:
December 12, 2025

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